Publications

Zachariou V, Bauer CE, Pappas C, & Gold BT (2022). High Cortical Iron is Associated with the Disruption of White Matter Tracts Supporting Cognitive Function in Healthy Older Adults. Cerebral Cortex. 

Bauer CE, Zachariou V, Maillard P, Caprihan A, & Gold BT (2022). Multi-Compartment Diffusion MRI Models Link Tract-Related Characteristics with Working Memory Performance in Healthy Older Adults. Frontiers in Aging Neuroscience.

Maillard P, Hillmer LJ, Lu H, Arfanakis K, Gold BT, Bauer CE, Kramer JH, Staffaroni AM, Stables L, Wang DJJ, Seshadri S, Satizabal CL, Beiser A, Habes M, Fornage M, Rosenberg GA, Singh B, Singh H, Schwab K, Corriveau RA, Helmer KG, Greenberg SM, DeCarli C, & Caprihan A (2022). MRI Free Water as a Biomarker for Cognitive Performance: Validation in the MarkVCID Consortium. Alzheimer's & Dementia.

Libecap TJ, Zachariou V, Bauer CE, Wilcock DM, Jicha GA, Raslau FD & Gold BT (2022). Enlarged Perivascular Spaces are Negatively Associated with Montreal Cognitive Assessment Scores in Older Adults. Frontiers in Neurology. 

Zachariou V, Bauer CE, Powell DK & Gold BT (2022). Ironsmith: An Automated Pipeline for QSM-based Data Analyses. Neuroimage.

Ali DG, Bahrani AA, Barber JM, El Khouli RH, Gold BT, Harp JP, Jiang Y, Wilcock DM, Jicha GA. (2022). Amyloid-PET levels in the Precuneus and Posterior Cingulate Cortices are Associated with Executive Function Scores in Preclinical Alzheimer`s Disease Prior to Overt Global Amyloid Positivity. Journal of Alzheimer’s Disease 88: 1127-1135.

Maillard P, Lu H, Arfanakis K, Gold BT, Bauer CE, Zachariou V, Stables L, Wang DJJ, Jann K, Seshadri S, Duering M, Hillmer LJ , Rosenberg GA, Snoussi H, Sepehrband F,  Habes M, Singh B, Kramer JH, Corriveau RA, Singh H, Fischl B, Schwab K,  Helmer KG, Greenberg SM, Caprihan A, DeCarli C, Satizabal CL, for the MarkVCID Consortium (2022). Instrumental Validation of Free Water, Peak-Width of Skeletonized Mean Diffusivity and White Matter Hyperintensities: MarkVCID Neuroimaging kits. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

2021

Zachariou V, Bauer CE, Seago ER, Panayiotou G, Hall ED, Butterfield DA, & Gold BT. Healthy Dietary-Intake Reduces the Effects of Age on Brain Iron Concentration and Working Memory Performance. (2021). Neurobiology of Aging. 106: 183-196.

Bauer CE, Zachariou V, Seago E, & Gold BT (2021). White Matter Hyperintensity Volume and Location: Associations with WM Microstructure, Brain Iron and Cerebral Perfusion. Frontiers in Aging Neuroscience 5;13: 617947.

Liu P, Jiang D, Albert M, Bauer CE, Caprihan A, Gold BT, Greenberg SM, Helmer KG, Jann K, Jicha G, Rodriguez P, Satizabal CL, Seshadri S, Singh H, Thompson JF, Wang DJJ, Lu H (2021). Multi-vendor and multisite evaluation of cerebrovascular reactivity mapping using hypercapnia challenge. Neuroimage 15: 118754.

Bahrani AA, Smith CD, Barber JM, Al-Janabi OM, Powell DK, Andersen AH, Ramey BD, Abner EL, Goldstein LB, Winder Z, Gold BT, Van Eldik L, Wilcock DM, Jicha GA (2021). Development of a protocol to assess within-subject, regional white matter hyperintensity changes in aging and dementia. J Neurosci Methods 360: 109270. 

Gold BT, Shao X, Sudduth TL, Jicha GA, Wilcock DM, Seago ER, & Wang DJJ (2021). Water Exchange Rate across the Blood-Brain Barrier is Associated with CSF Amyloid-Beta42 in Healthy Older Adults. Alzheimer's & Dementia: The Journal of the Alzheimer's Association. 17: 2020-2029. 

Adams TG, Rippey CS, Kelly AR, Gold BT, & Pittenger C. (2021). Treatment of obsessive-compulsive disorder with frontopolar multifocal transcranial direct current stimulation and exposure and response prevention: A case series. Brain Stimulation 14: 1431-1433.

Lu H, Kashani AH, Arfanakis K, Caprihan A, DeCarli C, Gold BT, Maillard P, Satizabal CL, Stables L, Wang DJJ, Corriveau RA, Singh H, Smith EE, Fischl B, van der Kouwe A, Schwab K, Helmer KG & Greenberg SM; MarkVCID Consortium (2021) MarkVCID Cerebral small vessel consortium: II Neuroimaging protocols. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 17:716-725.

Blevins BL, Vinters HV, Love S, Wilcock DW, Grinberg LT, Schneider JA, Kalaria RN, Katsumata Y, Gold BT, Wang DJJ, Ma SJ, Shade LMP, Fardo DW, Hartz AMS,  Jicha GA, Magaki SD, Schmitt FA, Teylan MA, Ighodaro ET, Phe P, Abner EL, Cykowski MD, Van Eldik LJ, Nelson PT. (2021). Brain Arteriolosclerosis. Acta Neuropathologica 141:1-24.

Bauer CE, Brown CA & Gold BT; for the Alzheimer's Disease Neuroimaging Initiative (2020). Education does not Protect Cognitive Function from Brain Pathology in the ADNI 2 Cohort. Neurobiology of Aging 90:147-149.

Zachariou V, Bauer CE, Seago ER, Raslau FD, Powell DK, & Gold BT (2020). Cortical iron disrupts functional connectivity networks supporting working memory performance in older adults. Neuroimage.

Johnson NF, Bahrani AA, Powell DK, Jicha GA, & Gold BT (2020). Cardiorespiratory Fitness Diminishes the Effects of Age on White Matter Hyperintensity Volume. PLOS ONE.

Brown CA, Schmitt FA, Smith CD & Gold BT. Distinct Patterns of Default Mode and Executive Control Network Circuitry Contribute to Present and Future Executive Function in Older Adults. (2019). Neuroimage 195: 320-332.

Stern Y, Chételat G, Habeck C, Arenaza-Urquijo E, Vemuri P, Estanga A, Bartres-Faz D, Cantillon M, Clouston S, Elman J, Gold BT, Jones R, Kempermann G, Okonkwo O, Ying Lim Y, Van Loenhoud A, Martínez-Lage P, Morbelli S, Ossenkoppele R, Pettigrew C, Scarmeas N, Soldan A, Udeh-Momoh C, Valenzuela M, Vuoksimaa E, Rosen A. (2019). Mechanisms Underlying Resilience in Ageing. Nature Reviews Neuroscience 20: 246.

Johnson NF, Gold BT, Ross D, Bailey AL, Clasey JL, Gupta V, Leung S, & Powell DK. Non-Fasting High-Density Lipoprotein is Associated with White Matter Microstructure in Healthy Older Adults (2019). Frontiers in Aging Neuroscience 7;11: 100. 

Al-Janabi OM, Bauer CE, Goldstein L, Murphy R, Bahrani A, Smith CD, Wilcock D, Gold BT, Jicha GA. White Matter Hyperintensity Regression: Associations with Brain Atrophy and Cognition (2019). Brain Sciences 19;9(7). pii: E170.

Al-Janabi OM, Brown CA, Bahrani AA, Abner EL, Barber JM, Gold BT, Goldstein LB, Murphy RR, Nelson PT, Johnson NF, Shaw LM, Smith CD, Trojanowski JQ, Wilcock DM, & Jicha GA (2018). Distinct Spatial Distribution of White Matter Hyperintensities Associated with Alzheimer’s Disease Pathology and Hypertension. The Journal of Alzheimer’s Disease 66: 1095-1104.

Stern Y, Arenaza-Urquijo EM, Bartrés-Faz D, Belleville S, Cantilon M, Ewers M, Franzmeier N, Kempermann G, Kremen WS, Okonkwo O, Scarmeas N, Soldan A, Udeh-Momoh C, Valenzuela M, Prashanthi V, Vuoksimaa E, Gold B, Jones R, Habeck C, Ossenkoppele R and the Reserve, Resilience and Protective Factors PIA Empirical Definitions and Conceptual Frameworks Workgroup (2018). Whitepaper: Defining and investigating cognitive reserve, brain reserve and brain maintenance. Alzheimer’s & Dementia S1552-5260 (18): 33491-33495.

Lyons DN, Vekaria H, Macheda T, Bakshi V, Powell DK, Gold BT, Lin AL, Sullivan PG & Bachstetter AD (2018). A mild traumatic brain injury in mice produces lasting deficits in brain metabolism. Journal of Neurotrauma 35: 2435-2447.

Brown CA, Jiang Y, Smith CD & Gold BT (2018). Age and Alzheimer's pathology disrupt default mode network functioning via alterations in white matter microstructure but not hyperintensities. Cortex 104: 58-74.

Carmichael OT, Pillai S, Shankapal P, McLellan A, Kay DG, Gold BT, Keller JN (2018). A combination of essential fatty acids, panax ginseng extract, and green tea catechins modifies brain fMRI signals in healthy older adults. The Journal of Nutrition, Health & Aging 22:837-846.

Al-Janabi OM, Panuganti P, Abner EL, Nelson PT, Moser D, Gold BT, Smith CD, and Jicha, GA (2018). Global Cerebral Atrophy Detected by Routine Imaging: Relationship with Age, Hippocampal atrophy, and White Matter Hyperintensities. Journal of Neuroimaging 28: 301-306.

Johnson NF, Gold BT, Brown CA, Anggelis EF, Bailey AL, Clasey JL & Powell DK (2017). Endothelial Function is Associated with White Matter Microstructure and Executive Function in Older Adults. Frontiers in Aging Neuroscience 9: 255.

Gold BT, Brown CA, Hakun JG, Shaw LM Trojanowski JQ, & Smith CD (2017). Clinically Silent Alzheimer's and Vascular Pathologies Influence Brain Networks Supporting Executive Function in Healthy Older Adults. Neurobiology of Aging 58: 102-111.

Brown CA, Johnson NF, Anderson-Mooney AJ, Jicha GA, Shaw LM Trojanowski JQ, Van Eldik LJ, Schmitt FA, Smith CD, & Gold BT (2016). Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer’s disease. Neuroimage Clinical 13: 106-115.

Jiang Y, Huang H, Abner E, Broster LS, Jicha GA, Schmitt FA, Kryscio R, Andersen A, Powell DK, Van Eldik L, Gold BT, Nelson PT, Smith CS, Ding M (2016). Alzheimer’s Biomarkers Correlate with Brain Connectivity Differentially during Rest and Task but Are Not Associated with Cognition in Healthy Older Adults. Frontiers in Aging Neuroscience 8; 8:15.

Gold BT (2016). Lifelong Bilingualism, Cognitive Reserve and Alzheimer’s disease: A Review of Findings. Linguistic Approaches to Bilingualism 6:1/2. pp. 171-189. (Special Issue: “Aging and Bilingualism”).

Lin A, Powell D, Caban-Holt A, Jicha GA, Robertson W, Gold BT, Davis R, Abner E, Wilcock DM, Schmitt FAS, Head E (2016). 1H-MRS metabolites metabolites in adults with Down syndrome: Effects of dementia. NeuroImage: Clinical 11: 728-735.

Johnson NF, Gold BT, Bailey AL, Clasey JL, Hakun JG, White M, Long D, Powell DK (2016). Cardiorespiratory Fitness Modifies the Relationship between Myocardial Function and Cerebral Blood Flow in Older Adults. Neuroimage 131: 126-132

Head E. Powell D, Gold BT, Ling A, Wilcock DM, Schmitt FA (2016). In vivo Brain Imaging in Down Syndrome: Functional and Structural Similarities with Alzheimer’s Disease. In A. Salehi, M. Rafii and C. Phillips (Eds.) Recent Advances in Alzheimer Research Bentham Science Publishers, Chapter 7, 126-150.

Gold BT (2016). Bilingualism, Cognitive Reserve and Alzheimer’s disease: A Review of Findings. Linguistic Approaches to Bilingualism 6:1/2. pp. 171-189. (Special Issue: “Aging and Bilingualism”).

Brown CA, Hakun JG, Zhu Z, Johnson NF & Gold BT (2015). White matter microstructure contributes to age-related declines in task-induced deactivation of the default mode network. Frontiers in Aging Neuroscience 9;7:194.

Hakun JG, Zhu Z, Brown CA, Johnson NF, Gold BT (2015). Longitudinal Alterations to Brain Function, Structure, and Cognitive Performance in Healthy Older Adults: a fMRI-DTI study. Neuropsychologia 71, 225-235.

Gold BT (2015). Executive Control, Brain Aging and Bilingualism. Cortex 73: 369-370.

Hakun JG, Zhu Z, Johnson NF, Gold BT (2015). Evidence for Reduced Efficiency and Successful Compensation in Older Adults during Task Switching. Cortex 64, 352-362. PMCID: PMC4346415

Gold BT. Lifelong Bilingualism and Neural Reserve against Alzheimer's disease: A Review of Findings and Potential Mechanisms (2015). Behavioural Brain Research 281, 9-15. (Invited Article). PMCID: PMC4305453

Zhu Z, Gold BT, Chang C, Wang S, Juan C (2015). Left middle temporal and inferior frontal regions contribute to speed of lexical decision: A TMS study. Brain and Cognition 93, 11-17.

Abhilasha S, Gold BT, Smith CD, Castellani RJ, Khare M, Yu, H, Nguyen C, Lan M, Wencel M, Wigal S, Caiozzo V, Kimonis V (2015). A case report comparing clinical, imaging and neuropsychological assessment findings in twins discordant for the VCP p.R155C mutation. Neuromuscular Disorders 25, 177-83.

Smith CD, & Gold BT (2015). Neuroimaging of Alzheimer’s disease. In L Saba (ed.) Imaging in Neurodegenerative Disorders. New York: Oxford University Press, pp. 181-198.

Smith CD, Grondin R, LeMaster W, Martin B, Gold BT, Ain KB (2015). Quantified Cognitive, Motor and Driving Impairments in Hypothyroidism and Their Reversibility. Thyroid 25, 28-36.

Zhu Z, Johnson NF, Kim C, Gold BT (2015). Reduced frontal cortex efficiency is associated with lower white matter integrity in aging. Cerebral Cortex 25, 138-146.   

Zhu Z, Hakun JG, Johnson NF, & Gold BT (2014). Age-related increases in right frontal activation during task switching are mediated by reaction time and white matter microstructure. Neuroscience 278, 51-61. PMCID: PMC4194212

Gold BT, Zhu Z, Brown CA, Andersen AH, LaDu MJ, Tai L, Jicha GA, Kryscio RJ, Estus S, Nelson PT, Scheff SW, Abner E, Schmitt FA, Van Eldik LJ, & Smith CD (2014). White matter integrity is associated with CSF markers of AD in normal adults. Neurobiology of Aging 35, 2263-2271.

Powell DK, Caban-Holt A, Jicha GA, Robertson WC, Davis R, Gold BT, Schmitt FAS, Head E (2014). Frontal white matter integrity in adults with Down syndrome with and without Dementia. Neurobiology of Aging 35, 1562-1569. PMCID: PMC3992921.

Kim C, Johnson NF, Gold BT (2014). Conflict adaptation in prefrontal cortex: Now you see it, now you don’t. Cortex 50: 76-85. PMCID: PMC3872513

Gold BT, Johnson NF, Powell DK (2013). Lifelong Bilingualism Contributes to Cognitive Reserve against White Matter Integrity Declines in Aging. Neuropsychologia 51: 2841-2846.

Dien J, Brian E, Molfese DL, & Gold BT (2013). Combined ERP/fMRI evidence for early word recognition effects in the posterior inferior temporal gyrus. Cortex 49: 2307-2321.

Gold BT, Kim C, Johnson NF, Kryscio RJ, & Smith CD (2013). Lifelong bilingualism maintains neural efficiency for cognitive control in aging. The Journal of Neuroscience 33: 387-396.

Johnson NF, Kim C, & Gold BT (2013). Socioeconomic Status is Positively Correlated with Frontal White Matter Integrity in Aging. Age 35: 2045-56. 

Head E, Powell D, Gold BT, & Schmitt FA (2012). Alzheimer’s disease in Down syndrome.  European Journal of Neurodegenerative Diseases 1: 353-364.

Smith CD, Andersen AH, & Gold BT (2012). Structural brain alterations before MCI in ADNI: Validation of volume loss in a predefined antero-temporal region. The Journal of Alzheimer’s Disease 31: 49-58. (Invited Article for Special Issue: “Predictive Biomarkers for Alzheimer's Disease Using State-of-the-Art Brain Imaging Techniques”).

Gold BT, Jiang Y, Powell DK, & Smith CD (2012). Multimodal imaging evidence for axonal and myelin deterioration in amnestic mild cognitive impairment. The Journal of Alzheimer’s Disease 31: 19-31. (Invited Article for Special Issue: “Predictive Biomarkers for Alzheimer's Disease Using State-of-the-Art Brain Imaging Techniques”).

Gold BT, & Keller JN (2012). Preface to Special Issue ‘Imaging Brain Aging and Neurodegenerative Disease’ in BBA – Molecular Basis of Disease 1822: 315-316.

Kim C, Johnson NF & Gold BT (2012). Common and distinct neural mechanisms of attention switching and response conflict. Brain Research 1469: 92-102. PMCID: PMC3411858

Gold BT, Johnson NF, Powell DK, Smith CD (2012). White matter integrity and vulnerability to Alzheimer's disease: Preliminary findings and future directions.  BBA – Molecular Basis of Disease 1822: 416-422. PMCID: PMC3213315

Johnson NF, Kim C, Clasey J, Bailey A, & Gold BT (2012). Cardiorespiratory Fitness is Positively Correlated with Cerebral White Matter Integrity in Healthy Seniors. Neuroimage 59: 1514-1523. PMCID: PMC3230672

Kim C, Cilles SE, Johnson NF, & Gold BT (2012). Domain general and domain preferential brain regions associated with different types of task switching: A meta-analysis. Human Brain Mapping 33: 130-142. PMCID: PMC3421461

Threlkeld Z, Jicha GA, Smith CD, & Gold BT (2011). Task deactivation reductions and atrophy within parietal default mode regions are overlapping but only weakly correlated in mild cognitive impairment. The Journal of Alzheimer’s Disease 27: 415-427. PMCID: PMC3410647

Kim C, Johnson NF, Cilles SE, & Gold BT (2011). Common and distinct mechanisms of cognitive flexibility in prefrontal cortex. The Journal of Neuroscience 31: 4771-4779. PMCID: PMC3086290

Gold BT, Powell DK, Andersen AH, Smith CD (2010). Alterations in multiple measures of white matter integrity in normal women at high risk for Alzheimer's disease. Neuroimage 52:1487-1494. PMCID: PMC2910213

Gold BT, Jiang Y, Jicha GA, & Smith CD (2010). Functional response in ventral temporal cortex differentiates mild cognitive impairment from normal aging. Human Brain Mapping 31: 1249-1259. PMCID: PMC3004147

Smith CD, Chebrolu H, Andersen AH, Powell DA, Lovell MA, Xiong S, & Gold BT (2010). White matter diffusion alterations in normal women at risk of Alzheimer's disease. Neurobiology of Aging 31: 1122-1131. PMCID: PMC2873054

Martin SB, Smith CD, Collins HR, Schmitt FA, & Gold BT (2010). Evidence that volume of anterior medial temporal lobe is reduced in seniors destined for mild cognitive impairment. Neurobiology of Aging 31: 1099-1106. PMCID: PMC2873058

Zhang Q, Li, X, Gold BT, & Jiang Y (2010). Neural correlates of cross-domain affective priming. Brain Research 1329: 142-151. PMCID: PMC2857548

Gold BT, Powell DK, Xuan L, Jicha GA, & Smith CD (2010). Age-related slowing of task switching is associated with decreased integrity of frontoparietal white matter. Neurobiology of Aging 31: 512-522. PMCID: PMC2815097

Gold BT, Andersen AH, Jicha GA, & Smith CD (2009). Aging influences the neural correlates of lexical decision but not automatic semantic priming. Cerebral Cortex 19: 2671-2679. PMCID: PMC2758680

Jiang Y, Lianekhammy J, Lawson A, Guo C, Lynam D, Joseph JE, Gold BT, & Kelly TH (2009). Brain responses to repeated visual experience among low and high sensation seekers: role of boredom susceptibility. Psychiatry Research: Neuroimaging 173: 100-106.

Jiang Y, Ding J, Gold BT, & Powell DK (2008) Hemispheric asymmetries in tracking occluded moving targets with the mind’s eye: simultaneous event-related fMRI and eye-movement recording. Brain Imaging and Behavior 2: 300-308.

Gold BT & Rastle K (2007). Neural correlates of morphological decomposition during visual word recognition. Journal of Cognitive Neuroscience 19: 1983-1993.

Martin SB, Covell DJ, Joseph JE, Chebrolu H, Smith CD, Kelly T, Jiang, Y, & Gold BT (2007). Human novelty seeking correlates with hippocampus volume: convergent evidence from manual tracing and voxel-based morphometry. Neuropsychologia 45: 2874-2881. PMCID: PMC2971547

Gold BT, Powell, DK, Xuan L, Jiang Y, & Hardy, PA. (2007). Speed of lexical decision correlates with diffusion anisotropy in left parietal and frontal white matter:  evidence from diffusion tensor imaging.  Neuropsychologia 45: 2439-2446. PMCID: PMC2965058

Liu X, Powell DK, Wang H, Gold BT, Corbly CR, & Joseph HE (2007). Functional Dissociation in Frontal and Striatal Areas for Processing of Positive and Negative Reward Information. The Journal of Neuroscience 27: 4587-4597.

Gold BT, Balota DA, Jones SJ, Powell DK, Smith CD, & Andersen AH (2006). Dissociation of automatic and strategic lexical-semantics: Functional magnetic resonance imaging evidence for differing roles of multiple frontotemporal regions. The Journal of Neuroscience 26: 6523-6532.

Cortese MJ, Balota DA, Sergent-Marshall SD, Buckner RL, & Gold BT (2006). How consistency and regularity in past tense verb generation relate to Alzheimer’s Disease and semantic dementia. Cognitive Neuropsychology 23: 856-876.

Gold BT, Balota DA, Kirchhoff BA, & Buckner RL (2005) Common and dissociable activation patterns associated with controlled semantic and phonological processing: Evidence from fMRI adaptation. Cerebral Cortex 15:1438-1450. 

Gold BT, Balota DA, Cortese MJ, Sergent-Marshall SD, Snyder AZ, Salat DH, Fischl B, Dale AM, Morris JC, & Buckner RL (2005) Differing neuropsychological and neuroanatomical correlates of abnormal reading in early-stage semantic dementia and dementia of the Alzheimer type. Neuropsychologia 43: 833-846.

Kertesz A, & Gold BT (2003). Recovery of Cognition.  In KM Heilman & E Valenstein (eds.) Clinical neuropsychology (4th Edition). New York: Oxford University Press, pp. 617-639.

Gold BT, & Buckner RL (2002) Common prefrontal regions co-activate with dissociable posterior regions during controlled semantic and phonological tasks. Neuron 35: 803-812. 

Gold BT, & Kertesz A (2001) Phonologically related lexical repetition disorder: A case study. Brain and Language 77: 241-265.

Gold BT, & Kertesz A (2000) Right hemisphere semantic processing of visual words in an aphasic patient: An fMRI study. Brain and Language 73: 456-465.

Gold BT, & Kertesz A (2000) Preserved visual lexicosemantics in global aphasia: A right-hemisphere contribution? Brain and Language 75: 359-375. 

Goel V, Gold B, Kapur S, & Houle S (1998) Neuroanatomical correlates of human reasoning. Journal of Cognitive Neuroscience 10: 293-302.

Goel V, Gold B, Kapur S, & Houle S (1997) The seats of reason? An imaging study of deductive and inductive reasoning utilizing a PET 15O-labeled water technique. NeuroReport 8: 1305-1310.