Click HERE for the most up-to-date list of our publications!
Peer-Reviewed Publications
Note that * denotes corresponding author.
Temple University
2025
36. Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo. Vladimir V. Shuvaev, Ying K. Tam, Benjamin W. Lee, Jacob W. Myerson, Alan Herbst, Raisa Yu Kiseleva, Patrick M. Glassman, Hamideh Parhiz, Mohamad-Gabriel Alameh, Norbert Pardi, Hiromi Muramatsu, Tea I. Shuvaeva, Evguenia Arguiri, Oscar A. Marcos-Contreras, Elizabeth D. Hood, Taylor V. Brysgel, Jia Nong, Tyler E. Papp, Deborah M. Eaton, Rachel Riley, Rohan Palanki, Kiran Musunuru, Jacob S. Brenner, Michael J. Mitchell, Victor A. Ferrari, Barbara L. Mui, Sean C. Semple. Sherry A. Weppler, Pavan Atluri, Kenneth B. Margulies, Drew Weissman, Vladimir R. Muzykantov. Proceedings of the National Academy of Sciences of the USA. July 2025. https://www.pnas.org/doi/abs/10.1073/pnas.2409266122
35. Biomechanical and Functional Features of the Carrier Erythrocytes Prolonging Circulation Time of Biotherapeutic Targeted to Glycophorin A. Alina D. Peshkova, Taylor V. Brysgel, Parth Mody, Jia Nong, Zhicheng Wang, Jacob W. Myerson, Rustem I. Litvinov, John W. Weisel, Jacob S. Brenner, Patrick M. Glassman, Oscar A. Marcos-Contreras, Vladimir R. Muzykantov. Bioconjugate Chemistry. January 2025. https://pubs.acs.org/doi/10.1021/acs.bioconjchem.4c00522?articleRef=test
2024
34. Nanocarriers' repartitioning of drugs between blood subcompartments as a mechanism of improving pharmacokinetics, safety, and efficacy. Michael H. Zaleski, Serena Omo-Lamai, Jia Nong, Liam S. Chase, Jacob W. Myerson, Patrick M. Glassman, Florence Lee, Sahily Reyes-Esteves, Zhicheng Wang, Manthan N. Patel, Alina D. Peshkova, Hiroaki Komatsu, Paul H. Axelsen, Vladimir R. Muzykantov, Oscar A. Marcos-Contreras, Jacob S. Brenner. Journal of Controlled Release. October 2024. https://www.sciencedirect.com/science/article/pii/S0168365924005285
33. Development of a predictive algorithm for the efficacy of half-life extension strategies. Patrick M. Glassman. International Journal of Pharmaceutics. July 2024. https://www.sciencedirect.com/science/article/pii/S0378517324006161
32. Physiologically-based modeling of LNP-mediated delivery of mRNA in the vascular system. Hamideh Parhiz, Vladimir V. Shuvaev, Qin Li, Tyler E. Papp, Awurama A. Akyianu, Ruiqi Shi, Amir Yadegari, Hamna Shahnawaz, Sean C. Semple, Barbara L. Mui, Drew Weissman, Vladimir R. Muzykantov, Patrick M. Glassman. Molecular Therapy Nucleic Acids. March 2024. https://www.sciencedirect.com/science/article/pii/S2162253124000623
31. Targeting lipid nanoparticles to the blood brain barrier to ameliorate acute ischemic stroke. Jia Nong, Patrick M. Glassman, Vladimir V. Shuvaev, Sahily Reyes-Esteves, Helene C. Descamps, Raisa Y. Kiseleva, Tyler E. Papp, Mohamad-Gabriel Alameh, Ying K. Tam, Barbara L. Mui, Serena Omo-Lamai, Marco E. Zamora, Tea Shuvaeva, Evguenia Arguiri, Xijing Gong, Taylor V. Brysgel, Ai Wen Tan, Ashley G. Woolfork, Aalim Weljie, Christoph A. Thaiss, Jacob W. Myerson, Drew Weissman, Scott E. Kasner, Hamideh Parhiz, Vladimir R. Muzykantov, Jacob S. Brenner, Oscar A. Marcos-Contreras. Molecular Therapy. March 2024. https://www.sciencedirect.com/science/article/pii/S152500162400145X
2023
30. Development and pharmacokinetic assessment of a fully canine anti-PD-1 monoclonal antibody for comparative translational research in dogs with spontaneous tumors. Sho Yoshimoto, Nicholas Chester, Ailian Xiong, Enrico Radaelli, Hong Wang, Marc Brillantes, Gayathri Gulendran, Patrick Glassman, Don L. Siegel, Nicola J. Mason. mAbs. December 2023. https://www.tandfonline.com/doi/full/10.1080/19420862.2023.2287250
29. Effective Prevention of Arterial Thrombosis with Albumin-Thrombin Inhibitor Conjugates. Oscar A. Marcos-Contreras, Jacob W. Myerson, Jia Nong, Jacob S. Brenner, Vladimir R. Muzykantov, Patrick M. Glassman. Molecular Pharmaceutics. October 2023. https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.3c00325
28. Targeted Nanocarriers Co-Opting Pulmonary Intravascular Leukocytes for Drug Delivery to the Injured Brain. Jia Nong, Patrick M. Glassman, Jacob W. Myerson, Viviana Zuluaga-Ramirez, Alba Rodriguez-Garcia, Alvin Mukalel, Serena Omo-Lamai, Landis R. Walsh, Marco E. Zamora, Xijing Gong, Zhicheng Wang, Kartik Bhamidipati, Raisa Y. Kiseleva, Carlos H. Villa, Colin F. Greineder, Scott E. Kasner, Drew Weissman, Michael J. Mitchell, Silvia Muro, Yuri Persidsky, Jacob S. Brenner, Vladimir R. Muzykantov, Oscar A. Marcos Contreras. ACS Nano. July 2023. https://pubs.acs.org/doi/10.1021/acsnano.2c08275
27. Meta-Analysis of Material Properties Influencing Nanoparticle Plasma Pharmacokinetics. Briana Macedo, Manthan Patel, Michael H. Zaleski, Parth Mody, Xiaonan Ma, Patrick Mei, Jacob W. Myerson, Jacob S. Brenner, Patrick M. Glassman*. International Journal of Pharmaceutics. April 2023. https://www.sciencedirect.com/science/article/pii/S037851732300371X
26. Targeted drug delivery to the brain endothelium dominates over passive delivery via vascular leak in experimental intracerebral hemorrhage. Sahily Reyes-Esteves, Jia Nong, Patrick M. Glassman, Serena Omo-Lamai, Sarah Ohashi, Jacob W. Myerson, Marco E. Zamora, Xiaonan Ma, Scott E. Kasner, Lauren Sansing, Vladimir R. Muzykantov, Oscar A. Marcos Contreras, Jacob S. Brenner. Journal of Controlled Release. April 2023. https://www.sciencedirect.com/science/article/pii/S0168365923001499
University of Pennsylvania
2023
25. Mechanisms by Which Liposomes Improve Inhaled Drug Delivery for Alveolar Diseases. Laura T. Ferguson, Xiaonan Ma, Jacob W. Myerson, Jichuan Wu, Patrick M. Glassman, Marco E. Zamora, Elizabeth D. Hood, Michael Zaleski, Mengwen Shen, Eno-Obong Essien, Vladimir V. Shuvaev, Jacob S. Brenner. Advanced NanoBiomed Research. January 2023. onlinelibrary.wiley.com/doi/10.1002/anbr.202200106
2022
24. Targeted In Vivo Loading of Red Blood Cells Markedly Prolongs Nanocarrier Circulation. Patrick M. Glassman, Carlos H. Villa, Oscar A. Marcos-Contreras, Elizabeth D. Hood, Landis R. Walsh, Colin F. Greineder, Tea Shuvaeva, Laura Puentes, Jacob S. Brenner, Don L. Siegel, Vladimir R. Muzykantov. Bioconjugate Chemistry. June 2022. https://pubs.acs.org/doi/10.1021/acs.bioconjchem.2c00196
23. Targeting vascular inflammation through emerging methods and drug carriers. Jia Nong, Patrick M. Glassman*, Vladimir R. Muzykantov. Advanced Drug Delivery Reviews. May 2022. https://www.sciencedirect.com/science/article/abs/pii/S0169409X22000709?via%3Dihub
22. Combating Complement's Deleterious Effects on Nanomedicine by Conjugating Complement Regulatory Proteins to Nanoparticles. Zhicheng Wang, Elizabeth D. Hood, Jia Nong, Jing Ding, Oscar A. Marcos-Contreras, Patrick M. Glassman, Kathryn M. Rubey, Michael Zaleski, Carolann L Espy, Damodara Gullipali, Takashi Miwa, Vladimir R. Muzykantov, Wen-Chao Song, Jacob W. Myerson, Jacob S. Brenner. Advanced Materials. February 2022. https://onlinelibrary.wiley.com/doi/10.1002/adma.202107070
21. Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation. Jacob W. Myerson, Priyal N. Patel, Kathryn M. Rubey, Marco E. Zamora, Michael H. Zaleski, Nahal Habibi, Landis R. Walsh, Yi-Wei Lee, David C. Luther, Laura T. Ferguson, Oscar A. Marcos-Contreras, Patrick M. Glassman, Liudmila L Mazaleuskaya, Ian Johnston, Elizabeth D. Hood, Tea Shuvaeva, Jichuan Wu, Hong-Ying Zhang, Jason V. Gregory, Raisa Y. Kiseleva, Jia Nong, Tilo Grosser, Colin F. Greineder, Samir Mitragotri, George S. Worthen, Vincent M. Rotello, Joerg Lahann, Vladimir R. Muzykantov, Jacob S. Brenner. Nature Nanotechnology. January 2022. https://www.nature.com/articles/s41565-021-00997-y
2021
20. Red blood cells: The metamorphosis of a neglected carrier into the natural mothership for artificial nanocarriers. Patrick M. Glassman, Elizabeth D. Hood, Laura T. Ferguson, Zongmin Zhao, Don L. Siegel, Samir Mitragotri, Jacob S. Brenner, Vladimir R. Muzykantov. Advanced Drug Delivery Reviews. November 2021. https://www.sciencedirect.com/science/article/abs/pii/S0169409X21003859?via%3Dihub
19. Development of a fully canine anti-canine CTLA4 monoclonal antibody for comparative translational research in dogs with spontaneous tumors. Nicola J. Mason, Nicholas Chester, Ailian Xiong, Antonia Rotolo, Ying Wu, Sho Yoshimoto, Patrick Glassman, Gayathri Gulendran, Don L. Siegel. mAbs. December 2021. https://www.tandfonline.com/doi/full/10.1080/19420862.2021.2004638
2020
18. Target-mediated exposure enhancement: a previously unexplored limit of TMDD. Patrick M. Glassman*, Vladimir R. Muzykantov. Journal of Pharmacokinetics and Pharmacodynamics. October 2020. https://link.springer.com/article/10.1007/s10928-020-09693-1
17. Bivalent engagement of endothelial surface antigens is critical to prolonged surface targeting and protein delivery in vivo. Raisa Yu Kiseleva, Patrick Glassman, Katie M. LeForte, Landis R. Walsh, Carlos H. Villa, Vladimir V. Shuvaev, Jacob W. Myerson, Pavel A. Aprelev, Oscar A. Marcos-Contreras, Vladimir R. Muzykantov, Colin F. Greineder. FASEB Journal. September 2020. https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201902515RR
16. Targeting drug delivery in the vascular system: Focus on endothelium. Patrick M. Glassman*, Jacob W. Myerson, Laura T. Ferguson, Raisa Y. Kiseleva, Vladimir V. Shuvaev, Jacob S. Brenner, Vladimir R. Muzykantov. Advanced Drug Delivery Reviews. June 2020. https://www.sciencedirect.com/science/article/abs/pii/S0169409X20300594?via%3Dihub
15. Vascular Drug Delivery Using Carrier Red Blood Cells: Focus on RBC Surface Loading and Pharmacokinetics. Patrick M. Glassman*, Carlos H. Villa, Anvay Ukidve, Zongmin Zhao, Paige Smith, Samir Mitragotri, Alan J. Russell, Jacob S. Brenner, Vladimir R. Muzykantov. Pharmaceutics. May 2020. https://www.mdpi.com/1999-4923/12/5/440
14. Molecularly Engineered Nanobodies for Tunable Pharmacokinetics and Drug Delivery. Patrick M. Glassman, Landis R. Walsh, Carlos H. Villa, Oscar A. Marcos-Contreras, Elizabeth D. Hood, Vladimir R. Muzykantov, Colin F. Greineder. Bioconjugate Chemistry. April 2020. https://pubs.acs.org/doi/10.1021/acs.bioconjchem.0c00003
13. Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier. Oscar A. Marcos-Contreras, Colin F. Greineder, Raisa Yu Kiseleva, Hamideh Parhiz, Landis R. Walsh, Viviana Zuluaga-Ramirez, Jacob W. Myerson, Eizabeth D. Hood, Carlos H. Villa, Istvan Tombacz, Norbert Pardi, Alecia Seliga, Barbara L. Mui, Ying K. Tam, Patrick M. Glassman, Vladimir V. Shuvaev, Jia Nong, Jacob S. Brenner, Makan Khoshnejad, Tom Madden, Drew Weissmann, Yuri Persidsky, Vladimir R. Muzykantov. Proceedings of the National Academy of Sciences of the USA. Februrary 2020. https://www.pnas.org/doi/10.1073/pnas.1912012117?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
2019
12. Pharmacokinetic and Pharmacodynamic Properties of Drug Delivery Systems. Patrick M. Glassman, Vladimir R. Muzykantov. Journal of Pharmacology and Experimental Therapeutics. September 2019. https://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=30837281
2018
11. Flexible Nanoparticles Reach Sterically Obscured Endothelial Targets Inaccessible to Rigid Nanoparticles. Jacob W. Myerson, Bruce Braender, Olivia McPherson, Patrick M. Glassman, Raisa Y. Kiseleva, Vladimir V. Shuvaev, Oscar Marcos-Contreras, Martha E. Grady, Hyun-Su Lee, Colin F. Greineder, Radu V. Stan, Russell J. Composto, David M. Eckmann, Vladimir R. Muzykantov. Advanced Materials. August 2018. https://onlinelibrary.wiley.com/doi/10.1002/adma.201802373
10. Targeting therapeutics to endothelium: are we there yet? Raisa Yu Kiseleva, Patrick M. Glassman, Colin F. Greineder, Elizabeth D. Hood, Vladimir V. Shuvaev, Vladimir R. Muzykantov. Drug Delivery and Translational Research. August 2018. https://link.springer.com/article/10.1007/s13346-017-0464-6
9. The new frontiers of the targeted interventions in the pulmonary vasculature: precision and safety (2017 Grover Conference Series). Jacob S. Brenner, Raisa Yu Kiseleva, Patrick M. Glassman, Hamideh Parhiz, Colin F. Greineder, Elizabeth D. Hood, Vladimir V. Shuvaev, Vladimir R. Muzykantov. Pulmonary Circulation. January 2018. https://journals.sagepub.com/doi/full/10.1177/2045893217752329?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org
2017
8. Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions. Jacob S. Brenner, Kartik Bhamidipati, Patrick M. Glassman, N Ramakrishnan, Depeng Jiang, Andrew J. Paris, Jacob W. Myerson, Daniel C. Pan, Vladimir V. Shuvaev, Carlos H. Villa, Elizabeth D. Hood, Raisa Kiseleva, Colin F. Greineder, Ravi Radhakrishnan, Vladimir R. Muzykantov. Nanomedicine. May 2017. https://www.sciencedirect.com/science/article/pii/S1549963416302362?via%3Dihub
SUNY at Buffalo
2019
7. Physiologically-based modeling of monoclonal antibody pharmacokinetics in drug discovery and development. Patrick M. Glassman, Joseph P. Balthasar. Drug Metabolism and Pharmacokinetics. February 2019. https://www.sciencedirect.com/science/article/pii/S1347436718301332?via%3Dihub
2017
6. Physiologically-based modeling to predict the clinical behavior of monoclonal antibodies directed against lymphocyte antigens. Patrick M. Glassman, Joseph P. Balthasar. mAbs. February 2017. https://www.tandfonline.com/doi/full/10.1080/19420862.2016.1261775
2016
5. Physiologically-based pharmacokinetic modeling to predict the clinical pharmacokinetics of monoclonal antibodies. Patrick M. Glassman, Joseph P. Balthasar. Journal of Pharmacokinetics and Pharmacodynamics. August 2016. https://link.springer.com/article/10.1007/s10928-016-9482-0
4. Application of a catenary PBPK model to predict the disposition of "catch and release" anti-PCSK9 antibodies. Patrick M. Glassman, Joseph P. Balthasar. International Journal of Pharmaceutics. May 2016. https://www.sciencedirect.com/science/article/pii/S0378517316302757?via%3Dihub
2015
3. Scale-up of a physiologically-based pharmacokinetic model to predict the disposition of monoclonal antibodies in monkeys. Patrick M. Glassman, Yang Chen, Joseph P. Balthasar. Journal of Pharmacokinetics and Pharmacodynamics. October 2015. https://link.springer.com/article/10.1007/s10928-015-9444-y
2. Assessments of antibody biodistribution. Patrick M. Glassman, Lubna Abuqayyas, Joseph P. Balthasar. Journal of Clinical Pharmacology. March 2015. https://accp1.onlinelibrary.wiley.com/doi/10.1002/jcph.365
2014
1. Mechanistic considerations for the use of monoclonal antibodies for cancer therapy. Patrick M. Glassman, Joseph P. Balthasar. Cancer Biology and Medicine. March 2014. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969805/
Conference Abstracts
2024
Kishore Pathivada, Patrick M. Glassman. Pharmacologic characterization of engineered tissue plasminogen activator derivatives. Delaware Valley Drug Metabolism Discussion Group Fall Symposium. Langhorne, PA.
Jia Nong, Zhicheng Wang, Xijing Gong, Taylor Brysgel, Jacob Myerson, Oscar Marcos-Contreras, Jacob S. Brenner, Patrick Glassman, Vladimir R. Muzykantov. Avidity-dependent organ selective delivery of VCAM-targeted lipid nanoparticles. Biomedical Engineering Society Annual Meeting. Baltimore, MD.
Patrick M. Glassman. Analysis of the impact of half-life extension on primary pharmacokinetic parameters. Drug Metabolism GRC. Holderness, NH.
Hamideh Parhiz, Vladimir V. Shuvaev, Drew Weissman, Vladimir R. Muzykantov, Patrick M. Glassman. Translational pharmacokinetic/pharmacodynamic modeling of targeted mRNA-LNP therapeutics. American Society of Pharmacology and Experimental Therapeutics Annual Meeting. Arlington, VA.
2023
Alina D. Peshkova, Taylor V. Brysgel, Parth Mody, Jia Nong, Zhicheng Wang, Jacob W. Myerson, Rustem I. Litvinov, John W. Weisel, Vladimir R. Muzykantov, Patrick M. Glassman, Oscar A. Marcos-Contreras. Functional and Morphological Characterization of RBCs Loaded with Factor IX Conjugated with an Anti-Glycophorin A Antibody. American Society of Hematology Annual Meeting. San Diego, CA.
Oscar A. Marcos-Contreras, Jacob W. Myerson, Jia Nong, Vladimir R. Muzykantov, Patrick M. Glassman. Pharmacokinetically-driven engineering of anti-thrombotic agents. Drug Metabolism GRC. Holderness, NH.
Sahily Reyes-Esteves, Jia Nong, Patrick M. Glassman, Scott E. Kasner, Oscar A. Marcos-Contreras, Jacob S. Brenner. Endothelial targeting as a therapeutic delivery strategy in experimental intracerebral hemorrhage. European Stroke Organization Congress 2023. Munich, Germany.
Hamideh Parhiz, Vladimir V. Shuvaev, Drew Weissman, Vladimir R. Muzykantov, Patrick M. Glassman. Bridging the pharmacokinetic-pharmacodynamic gap for nucleic acid delivery. ACS Spring 2023 Meeting. Indianapolis, IN.
Jia Nong, Patrick M. Glassman, Vladimir V. Shuvaev, Sahily Reyes-Esteves, Helene C. Descamps, Raisa Y. Kiseleva, Mohamad-Gabriel Alameh, Ying K. Tam, Barbara L. Mui, Marco Zamora, Serena Omo-Lamai, Tea Shuvaeva, Evguenia Arguiri, Christoph A. Thaiss, Hamideh Parhiz, Jacob W. Myerson, Drew Weissman, Scott E. Kasner, Vladimir R. Muzykantov, Jacob S. Brenner, Oscar A. Marcos-Contreras. Vascular Cellular Adhesion Molecule Targeting to Restore Blood Brain Barrier Homeostasis in Acute Ischemic Stroke. CSHL Brain Barriers. Cold Spring Harbor, NY.
Sahily Reyes-Esteves, Jia Nong, Patrick M. Glassman, Scott E. Kasner, Oscar A. Marcos-Contreras, Jacob S. Brenner. Endothelial targeting is superior to passive delivery as a therapeutic strategy in acute intracerebral hemorrhage. CSHL Brain Barriers. Cold Spring Harbor, NY.
2022
Patrick M. Glassman, Hamideh Parhiz, Vladimir V. Shuvaev, Drew Weissman, Vladimir R. Muzykantov. Physiologically-based modeling of targeted mRNA-LNP delivery. GRC on Drug Carriers in Biology and Medicine. Mount Snow, VT.
Jia Nong, Patrick Glassman, Zhicheng Wang, Oscar Marcos-Contreras, Jacob Brenner, Vladimir Muzykantov. Density of conjugated antibody determines the extent of complement activation and targeting efficacy. Experimental Biology. Philadelphia, PA.
2021
Oscar A. Marcos-Contreras, Patrick M. Glassman, Jia Nong, Landis R. Walsh, Alba Rodriguez-Garcia, Jacob W. Myerson, Viviana Zuluaga-Ramirez, Colin F. Greineder, Elizabeth D. Hood, Raisa Y. Kiseleva, Sahily Reyes-Esteves, Silvia Muro, Scott E. Kasner, Yuri Persidsky, Jacob S. Brenner, Vladimir R. Muzykantov. Direct targeting of migrating white blood cells to restore blood-brain barrier homeostasis. Controlled Release Society Annual Meeting.
Oscar A. Marcos-Contreras, Jia Nong, Patrick M. Glassman, Raisa Y. Kiseleva, Michael Zaleski, Serena Omo-Lamai, Sahily Reyes-Esteves, Helene C. Descamps, Christoph A. Thaiss, Scott E. Kasner, Drew Weissman, Jacob S. Brenner, Vladimir R. Muzykantov. Vascular cellular adhesion molecule targeting to enhance the blood brain barrier in acute neurovascular inflammation. CSHL Brain Barriers.
Jia Nong, Oscar Marcos-Contreras, Patrick Glassman, Jacob Brenner, Vladimir Muzykantov. Nanocarriers targeting intercellular adhesion molecule enhance delivery to the inflamed brain. Experimental Biology.
Oscar A. Marcos-Contreras, Patrick M. Glassman, Jia Nong, Landis Walsh, Viviana Zuluaga-Ramirez, Alba Rodriguez-Garcia, Raisa Y. Kiseleva, Colin F. Greineder, Elizabeth D. Hood, Carlos H. Villa, Jacob W. Myerson, Jacob Brenner, Yuri Persidsky, Vladimir R. Muzykantov. Nanoparticles targeting the inflammatory network in acute neurovascular inflammation: lungs to brain axis. International Stroke Conference.
Jia Nong, Oscar A. Marcos-Contreras, Raisa Kiseleva, Patrick Glassman, Helene Descamps, Christoph Thaiss, Drew Weissman, Jacob Brenner, Vladimir R. Muzykantov. Vascular cellular adhesion molecule targeting for the treatment of acute neurovascular inflammation. International Stroke Conference.
2020
Jia Nong, Oscar A. Marcos Contreras, Patrick M. Glassman, Vladimir R. Muzykantov. Reteplase encapsulated in minocycline-containing nanoparticles retains thrombolytic activity. Experimental Biology.
2019
Oscar A. Marcos-Contreras, Patrick M. Glassman, Colin Greineder, Viviana Zuluaga-Ramirez, Jia Nong, Landis Walsh, Raisa Y. Kiseleva, Alba Rodriguez, Elizabeth Hood, Carlos H. Villa, Jacob W. Myerson, Jacob S. Brenner, Yuri Persidsky, Vladimir Muzykantov. Leukocytes hitchhike to the inflamed brain nanoparticles targeted to ICAM-1. Philadelphia Workshop of Hemostasis, Thrombosis, and Atherosclerosis. Philadelphia, PA
Oscar A. Marcos-Contreras, Colin Greineder, Viviana Zuluaga-Ramirez, Patrick M. Glassman, Landis Walsh, Raisa Y. Kiseleva, Elizabeth D. Hood, Carlos Villa, Jacob W. Myerson, Jacob S. Brenner, Yuri Persidsky, Vladimir R. Muzykantov. Targeted nanoparticles to migrating leukocytes in the inflamed brain. American Heart Association Scientific Sessions. Philadelphia, PA.
Patrick M. Glassman, Vladimir R. Muzykantov. Target-Mediated Exposure Enhancement - A New Limit of TMDD? American Conference on Pharmacometrics. Orlando, FL.
Raisa Y Kiseleva, Katie M. LeForte, Oscar Marcos-Contreras, Patrick M. Glassman, Colin F. Greineder, Vladimir R. Muzykantov. Endothelial targeting of thrombomodulin-based biotherapeutics: pharmacokinetics study and therapeutic window assessment of protein conjugates vs. gene therapy approaches. Controlled Release Society Annual Meeting. Valencia, Spain.
2018
Patrick M. Glassman, Colin F. Greineder, Landis R. Walsh, Vladimir R. Muzykantov. Engineered antibody-derived proteins for tunable pharmacokinetics and biodistribution. Center for Targeted Therapeutics and Translational Nanomedicine Symposium. Philadelphia, PA.
Patrick M. Glassman, Landis R. Walsh, Carlos H. Villa, Vladimir R. Muzykantov, Colin F. Greineder. Engineered nanobodies for targeted drug delivery to the inflamed neurovasculature. AAPS PharmSci 360. Washington, D.C.
Oscar A. Marcos-Contreras, Raisa Y. Kiseleva, Patrick M. Glassman, Carlos H. Villa, Jacob W. Myerson, Jacob S. Brenner, Silvia Muro, Vladimir R. Muzykantov. Features of molecular bridge between surface of carrier red blood cell (RBC) and cargo proteins regulate their vascular transfer. GRC on Drug Carriers in Medicine and Biology. West Dover, VT.
Jacob S. Brenner, Jacob W. Myerson, Priyal N. Patel, Patrick M. Glassman, Vladimir R. Muzykantov. Nanoparticles targeted to pulmonary intravascular leukocytes for the early and specific detection of acute respiratory distress syndrome. American Thoracic Society International Conference. San Diego, CA.
Colin Greineder, Oscar Marcos-Contreras, Landis Walsh, Patrick Glassman, Elizabeth Hood, Yuri Persidsky, Vladimir Muzykantov. Targeting vascular cell adhesion molecule-1 dramatically enhances drug delivery to the inflamed cerebrovasculature. Society for Academic Emergency Medicine Annual Meeting. Indianapolis, IN.
2017
Patrick M. Glassman, Colin F. Greineder, Landis R. Walsh, Vladimir R. Muzykantov. Molecular engineering of camelids for altered pharmacokinetics and biodistribution. Center for Targeted Therapeutics and Translational Nanomedicine Symposium. Philadelphia, PA.
Carlos H. Villa, Oscar A. Marcos-Contreras, Colin F. Greineder, Elizabeth D. Hood, Tea Shuvaeva, Landis R. Walsh, Jacob W. Myerson, Patrick M. Glassman, Jacob S. Brenner, Don L. Siegel, Vladimir R. Muzykantov. Red blood cell targeting of liposomes provides markedly enhanced circulation. Center for Targeted Therapeutics and Translational Nanomedicine Symposium. Philadelphia, PA.
Patrick M. Glassman, Jacob S. Brenner, Vladimir R. Muzykantov. Development of a mechanism-based pharmacokinetic model to predict the distribution of nanocarriers to healthy and injured regions of the lung. AAPS Annual Meeting. San Diego, CA.
Veena Thomas, Patrick Glassman, Joseph Balthasar. Development of a PBPK model for anti-transferrin (TfR) antibodies to predict brain and systemic pharmacokinetics. American Conference on Pharmacometrics. Fort Lauderdale, FL.
2015
Patrick M. Glassman, Joseph P. Balthasar. PBPK modeling of monoclonal antibodies conjugated to "residualizing" and "non-residualizing" radioisotopes. AAPS National Biotechnology Conference. San Francisco, CA.
2014
Patrick M. Glassman, Joseph P. Balthasar. Application of a catenary PBPK model to describe the disposition of "catch and release" antibodies. Buffalo Pharmaceutics Symposium. Buffalo, NY.
Patrick M. Glassman, Joseph P. Balthasar. Application of a catenary PBPK model to describe the disposition of "catch and release" antibodies. AAPS National Biotechnology Conference. San Diego, CA.