Giuseppe Gangarossa - Publications

Publications

1. Bakker W, Imbernon M, Gravesen Salinas C, Herrera Moro Chao D, Hassouna R, Morel C, Martin C, Meresse C, Denis R, Castel J, Peter A, Heni M, Maetzler W, Solvang Nielsen H, Duquenne M, Schwaninger M, Lundh S, Johan Hogendorf WF, Gangarossa G, Secher A, Hecksher-Sørensen J, Åskov Pedersen T, Prevot V, Luquet S. Acute changes in systemic glycaemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis. Cell Reports. 2022 Nov 22;41(8):111698. doi: 10.1016/j.celrep.2022.111698.

2. Onimus O, Valjent E, Fisone G, Gangarossa G*. Haloperidol-induced immediate early genes in striatopallidal neurons requires the converging action of cAMP/PKA/DARPP-32 and mTOR pathways. Int J Mol Sci. 2022 Oct 1;23(19):11637. doi: 10.3390/ijms231911637. (*corresponding author)

3. Dumont C, Li G, Castel J, Luquet S, Gangarossa G*. Hindbrain catecholaminergic inputs to the paraventricular thalamus scale feeding and metabolic efficiency in stress-related contexts. J Physiol. 2022 Jun;600(12):2877-2895. doi: 10.1113/JP282996. Epub 2022 Jun 1. (*corresponding author)

4. Luquet S*, Gangarossa G*. Dopamine drives food craving during pregnancy. Nat Metab. 2022 Apr 4. doi: 10.1038/s42255-022-00555-3. (*corresponding authors)

5. Berland C, Castel J, Terrasi R, Montalban E, Foppen E, Martin C, Muccioli GG, Luquet S, Gangarossa G*. Identification of an endocannabinoid gut-brain vagal mechanism controlling food reward and energy homeostasis. Molecular Psychiatry. 2022 Jan doi: 10.1038/s41380-021-01428-z; bioRxiv https://doi.org/10.1101/2020.11.14.382291 (*corresponding author)

6. Berland C, Small DM, Luquet S, Gangarossa G*. Dietary lipids as regulators of reward processes: multimodal integration matters. Trends Endocrinol Metab. 2021 Jun 17;S1043-2760(21)00123-5. doi: 10.1016/j.tem.2021.05.008. Online ahead of print. (*corresponding author)

7. Favier M, Pietrancosta N, El Mestikawy S, Gangarossa G*. Leveraging VGLUT3 functions to untangle brain dysfunctions. Trends Pharmacol Sci. 2021 Jun;42(6):475-490. doi: 10.1016/j.tips.2021.03.003. (*corresponding author)

8. Forner-Piquer I, Klement W, Gangarossa G, Zub E, de Bock F, Blaquiere M, Maurice T, Audinat E, Faucherre A, Lasserre F, Ellero-Simatos S, Gamet-Payrastre L, Jopling C, Marchi N. Varying modalities of perinatal exposure to a pesticide cocktail elicit neurological adaptations in mouse and zebrafish. Environmental Pollution. 2021 (accepted, https://doi.org/10.1016/j.envpol.2021.116755)

9. Valjent E*, Gangarossa G*. The Tail of the Striatum: from anatomy to connectivity and function. Trends Neurosci. 2020 Nov 23:S0166-2236(20)30249-6. doi: 10.1016/j.tins.2020.10.016 (* corresponding authors)

10. Gangarossa G, Luquet S. Hypothalamic regulation of glucose homeostasis: is the answer in the Matrix? Cell Metab. 2020 Nov 3;32(5):701-703. doi: 10.1016/j.cmet.2020.10.003

11. Klement W, Oliviero F, Gangarossa G, Zub E, De Bock F, Forner-Piquer I, Blaquiere M, Lasserre F, Pascussi JM, Maurice T, Audinat E, Ellero-Simatos S, Gamet-Payrastre L, Mselli-Lakhal L, Marchi N. Life-long DietaryPesticide Cocktail Induces Astrogliosis Along with Behavioral Adaptations and Activates p450 MetabolicPathways. Neuroscience. 2020 Oct 15;446:225-237. doi: 10.1016/j.neuroscience.2020.07.039.

12. Valverde S, Vandecasteele M, Piette C, Derousseaux W, Gangarossa G, Aristieta Arbelaiz A, Touboul J, Degos B, Venance L. Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms. Nat Commun. 2020 May 13;11(1):2388. doi: 10.1038/s41467-020-16046-6.

13. Berland C, Montalban E, Perrin E, Di Miceli M, Nakamura Y, Martinat M, Sullivan M, Davis XS, Shenasa MA, Martin C, Tolu S, Marti F, Caille S, Castel J, Perez S, Salinas CG, Morel C, Hecksher-Sørensen J, Cador M, Fioramonti X, Tschöp MH, Layé S, Venance L, Faure P, Hnasko TS, Small DM, Gangarossa G*, Luquet SH*. Circulating Triglycerides Gate Dopamine-Associated Behaviors through DRD2-Expressing Neurons. Cell Metab. 2020 Apr 7;31(4):773-790.e11. doi: 10.1016/j.cmet.2020.02.010. (* co-last and co-corresponding author).

14. Gangarossa G*, Perez S, Dembitskaya I, Prokin I,Berry H, Venance L. BDNF controls bidirectional endocannabinoid plasticity at corticostriatal synapses. Cereb Cortex. 2020 Jan 10;30(1):197-214. doi: 10.1093/cercor/bhz081.(* corresponding author)

15. Gangarossa G*, Castell L, Castro L, Tarot P, Veyrunes F, Vincent P, Bertaso F, Valjent E. Contrasting patterns of ERK activation in the tail of the striatum in response to aversive and rewarding signals. J Neurochem. 2019 Oct;151(2):204-226. doi: 10.1111/jnc.14804. (* corresponding author)

16. Mansouri-GuilaniN, Bernard V, Vigneault E, Vialou V, Daumas S, El Mestikawy S, Gangarossa G*. VGLUT3 gates psychomotor effects induced by amphetamine. J Neurochem. 2019 Mar;148(6):779-795. doi: 10.1111/jnc.14644 (* corresponding author)

17. Valjent E, Biever A,Gangarossa G, Puighermanal E. Dopamine signaling in the striatum. Adv Protein Chem Struct Biol. 2019;116:375-396. doi: 10.1016/bs.apcsb.2019.01.004.

18. Boussadia B, Lakhal L, Payrastre L, Ghosh C, Pascussi JM, Gangarossa G*, Marchi N*. Pregnane X receptor deletion modifies recognition memory and electroencephalographic activity. Neuroscience. 2017 Jul 23. pii: S0306-4522(17)30515-8 (* corresponding and co-last author)

19. Valtcheva S, Paillé V, Dembitskaya Y, Perez S, Gangarossa G, Fino E, Venance L. Developmental control of spike-timing-dependent plasticity by tonic GABAergic signaling in striatum. Neuropharmacology 2017 Jul 15;121:261-277

20. Boussadia B, Gangarossa G, Mselli-Lakhal L, Rousset MC, DeBock F, Lassere F, Ghosh C, Pascussi JM, Janigro D, Marchi N. Lack of CAR impacts neuronal function and cerebrovascular integrity in vivo. Experimental Neurology 2016 May 27;283(Pt A):39-48

21. Gangarossa G*, Guzman M, Prado V, Prado M, Daumas S, El Mestikawy S, Valjent E.Role of the atypical vesicular glutamate transporter VGLUT3 in l-DOPA-induced dyskinesia. Neurobiol Dis. 2016 Mar;87:69-79. doi: 10.1016/j.nbd.2015.12.010. (* corresponding author)

22. Gangarossa G*, Sakkaki S, Lory P, Valjent E. Mouse hippocampal phosphorylation footprint induced by generalized seizures: focus on ERK, mTORC1 and Akt/GSK3 pathway. Neuroscience 2015 Dec 17;311:474-83(* corresponding author)

23. Sakkaki S, Gangarossa G, Lerat B, Françon D, Forichon L, Chemin J, Valjent E, Lerner-Natoli M, Lory P. Blockade of T-type calcium channels prevents tonic-clonic seizures in a maximal electroshock seizure model. Neuropharmacology 2015 Oct 9;101:320-329

24. Polito M, Guiot E, Gangarossa G, Valjent E, Hervé D, Girault JA, Paupardin-Tritsch D, Castro L, Vincent P. Selective effects of PDE10A inhibitors on striatopallidal neurons require phosphatase inhibition by DARPP-32 (eNeuro) 10.1523/ENEURO.0060-15.2015

25. Biever A, Puighermanal E, Nishi A, David A, Panciatici C, Longueville C, Xirodimas D, Gangarossa G, Meyuhas O, Hervé D, Girault JA, Valjent E. PKA-dependent phosphorylation of ribosomal protein S6 does not correlate with translation efficiency in striatonigral and striatopallidal medium-sized spiny neurons. Journal of Neuroscience 2015 Mar 11;35(10):4113-30

26. Puighermanal E, Biever A, Espallergues J, Gangarossa G, De Bundel D, Valjent E. Drd2-Cre:RiboTag mouse line unraveled the molecular diversity of dopamine D2 receptor-expressing cells of the dorsal mouse hippocampus. Hippocampus 2015 Jul;25(7):858-75

27. Gangarossa G*, Ceolin L, Paucard A, Lerner-Natoli M, Perroy J, Fagni L, Valjent E. Repeated stimulation of dopamine D1-like receptor and hyperactivation of mTOR signaling lead to generalized seizures, altered dentate gyrus plasticity and memory deficits. Hippocampus, 2014 Dec;24(12):1466-81 (* corresponding author)

28. Gangarossa G*, Laffray S, Bourinet E, Valjent E. T-type calcium channel Ca_V3.2 deficient mice show elevated anxiety, impaired memory and reduced sensitivity to psychostimulants. Front Behav Neurosci. 2014 Mar 18; 8:92 (* corresponding author)

29. De Bundel D*, Gangarossa G*, Biever A, Bonnefont X, Valjent E. Cognitive dysfunction, elevated anxiety and reduced cocaine response in circadian clock-deficient cryptochrome knockout mice. Front Behav Neurosci. 2013 Oct 24;7:152 (* equal contribution)

30. Gangarossa G, Espallergues J, Mailly P, De Bundel D, de Kerchove d’Exaerde A, Hervé D, Girault JA, Valjent E, Krieger P. Spatial distribution of D1R- and D2R-expressing medium-sized spiny neurons differs along the rostro-caudal axis of the mouse dorsal striatum. Front Neural Circuits. 2013 Jul 29;7:124

31. Gangarossa G, Espallergues J, de Kerchove d’Exaerde A, El Mestikawy S, Gerfen CR, Hervé D, Girault JA, Valjent E. Distribution and compartmental organization of GABAergic medium-sized spiny neurons in the mouse Nucleus Accumbens. Front Neural Circuits. 2013 Feb 19;7:22

32. Gangarossa G, Valjent E. Regulation of the ERK pathway in the dentate gyrus by in vivo dopamine D1 receptor stimulation requires glutamatergic transmission. Neuropharmacology 2012, 63(6):1107-1117

33. Gangarossa G, Longueville S, De Bundel D, Perroy J, Herve D, Girault JA, Valjent E. Characterization of dopamine D1 and D2 receptor-expressing neurons in the mouse hippocampus. Hippocampus 2012, 22: 2199-2207

34. Santini E, Feyder M, Gangarossa G, Bateup HS, Greengard P, Fisone G. Dopamine- and cAMP-regulated Phosphoprotein of 32-kDa (DARPP-32)-dependent Activation of Extracellular Signal-regulated Kinase (ERK) and Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling in Experimental Parkinsonism. J Biol Chem 2012, 287(33):27806-27812

35. Guegan T, Cutando L, Gangarossa G, Santini E, Fisone G, Martinez A, Valjent E, Maldonado R, Martin M. Operant behavior to obtain palatable food modifies ERK activity in the brain reward circuit. Eur Neuropsychopharmacol. 2013 Mar;23(3):240-52. Epub 2012 May 12

36. Gangarossa G, Perroy J, Valjent E. Combinatorial topography and cell-type specific regulation of the ERK pathway by dopaminergic agonists in the mouse striatum. Brain Struct Funct. 2013 Mar;218(2):405-19. Epub 2012 Mar 28

37. Maioli S*, Gangarossa G*, Locchi F, Andrioli A, Bertini G, Rimondini R. Excitotoxic lesion of the perirhinal cortex impairs spatial working memory in a delayed-alternation task. Behav Brain Res 2012, 230(2):349-354. (* equal contribution)

38. Gangarossa G, Di Benedetto M, O'Sullivan GJ, Dunleavy M, Alcacer C, Bonito-Oliva A, Henshall DC, Waddington JL, Valjent E, Fisone G. Convulsant doses of a dopamine D1 receptor agonist result in Erk-dependent increases in Zif268 and Arc/Arg3.1 expression in mouse dentate gyrus. PLoS One 2011, 6(5):e19415

Submitted and/or Preprints

39. Montalban E, Walle R, Castel J, Ansoult A, Hassouna R, Foppen E, Fang X, Hutelin Z, Mickus S, Perszyk E, Petitbon A, Berthelet J, Rodrigues-Lima F, Cebrian-Serrano A, Gangarossa G, Martin C, Trifilieff P, Bosch-Bouju C, Small DM, Luquet S. The addiction-susceptibility TaqIA/Ankyrin repeat and kinase domain containing 1 kinase (ANKK1) controls reward and metabolism through dopamine receptor type 2 (DR2)-expressing neurons. (in revision at Biological Psychiatry). BioRxiv doi: https://doi.org/10.1101/2022.08.12.503577.

40. Castell L, Le Gall V, Cutando L, Petit CP, Puighermanal E, Kim H, Jercog D, Tarot P, Tassou A Harrus AG, Rubinstein M, Nouvian R, Rivat C, Trifilieff P, Gangarossa G, Janak P, Herry C, Valjent E. Dopamine D2 receptors in the extended amygdala scale the optimization of seeking and avoidance behaviors. (submitted to Neuropsychopharmacology)