Select Publications

For a complete list of publications, please see Pubmed.

Neuroprotective amyloid beta N-terminal peptides differentially alter human alpha7- and alpha7beta2-nicotinic acetylcholine (nACh) receptor single-channel properties.

Roberts CF, Cao Y, Im W, Nichols RA, Lukas RJ, and George AA. British Journal of Pharmacology (2024)

Analogs of α-conotoxin PnIC selectively inhibit α7β2- over α7-only subtype nicotinic acetylcholine receptors via a novel allosteric mechanism.

George AA, John SJ, Lucero LM, Eaton JB, Jaiswal E, Christensen SB, Gajewiak J, Watkins M, Cao Y, Olivera BM, Im W, McIntosh JM, Whiteaker P. The Journal of the The Federation of American Societies for Experimental Biology (2024)

A potential cost of evolving epibatidine resistance in poison frogs.

York JM, Borghese CM, George AA, Cannatella DC, Zakon HH. BMC Biology (2023)

Discoveries and future significance of research into amyloid-beta/α7-containing nicotinic acetylcholine receptor (nAChR) interactions.

Whiteaker P, George AA. Pharmacological Research (2023)

Implications of Oligomeric Amyloid-Beta (oAβ42) Signaling through α7β2-Nicotinic Acetylcholine Receptors (nAChRs) on Basal Forebrain Cholinergic Neuronal Intrinsic Excitability and Cognitive Decline.

George AA, Vieira JM, Xavier-Jackson C, Gee MT, Cirrito JR, Bimonte-Nelson HA, Picciotto MR, Lukas RJ, Whiteaker P. Journal of Neuroscience (2021)

Sleep-related hypermotor epilepsy associated mutations uncover important kinetic roles of α4β2- nicotinic acetylcholine receptor intracellular structures

Weltzin MM, George AA, Lukas RJ, Whiteaker P. Plos One (2021)

Distinctive single-channel properties of α4β2-nicotinic acetylcholine receptor isoforms

Weltzin MM, George AA, Lukas RJ, Whiteaker P. Plos One (2019)

Isoform-specific mechanisms of α3β4*-nicotinic acetylcholine receptor modulation by the prototoxin lynx1.

George AA, Bloy A, Miwa JM, Lindstrom JM, Lukas RJ, Whiteaker P. The Journal of the The Federation of American Societies for Experimental Biology (2017)

The prototoxin LYPD6B modulates heteromeric α3β4-containing nicotinic acetylcholine receptors, but not α7 homomers.

Ochoa V, George AA, Nishi R, Whiteaker P. The Journal of the The Federation of American Societies for Experimental Biology (2016)

Function of human α3β4α5 nicotinic acetylcholine receptors is reduced by the α5(D398N) variant.

George AA, Lucero LM, Damaj MI, Lukas RJ, Chen X, Whiteaker P. The Journal of Biological Chemistry (2012)

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