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Interested candidates with CSIR-JRF/UGC-JRF/Inspire fellowship are invited to join our research group. Send your CV to ganesh.clri@csir.res.in
Research Interest
Research Interest
Supramolecular Gels
Our research group focuses on the design and development of supramolecular gels derived from low molecular weight gelators (LMWGs), primarily based on amino acid derivatives and short peptide motifs. By harnessing non-covalent interactions such as hydrogen bonding, π–π stacking, electrostatic interactions, and hydrophobic effects, we aim to understand and control the self-assembly processes that drive gel formation. Our molecular design strategy encompasses the development of hydrogelators, organogelators, and ambidextrous gelators capable of gelling both aqueous and organic media, enabling versatile material platforms. Through systematic structure–property correlation studies, we engineer tunable, stimuli-responsive, and functional soft materials. These supramolecular gel systems are explored for diverse applications including drug delivery, antimicrobial materials, tissue engineering scaffolds, sensing platforms, and sustainable material technologies, with a strong emphasis on fundamental mechanistic understanding and translational impact.
Collagen Mimetic Peptides
Our research group focuses on the rational design and development of collagen-mimetic peptides (CMPs) that replicate the structural, mechanical, and biological features of native collagen. By precisely controlling peptide sequence, length, and functional motifs, we aim to engineer synthetic collagen-like systems capable of hierarchical self-assembly into triple helices, fibrils, and higher-order architectures.
A central theme of our work is to elucidate structure–assembly–function relationships governing CMP stability, supramolecular organization, and responsiveness to environmental cues such as pH, temperature, and ionic strength. We integrate peptide chemistry, biophysical characterization, and soft-matter approaches to tailor mechanical properties, biodegradability, and bioactivity.
Our research further explores the biomedical applications of collagen-mimetic materials, including extracellular matrix (ECM) mimics for tissue engineering, wound healing scaffolds, and platforms for controlled drug and biomolecule delivery. By bridging molecular design with functional performance, our goal is to develop next-generation collagen-inspired biomaterials with translational potential in regenerative medicine.
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