Publications
2026
Yang, H-J.*#, Park Hwang, Y., Park, M.… Lee, G.# “Gut Acetyl-L-Carnitine 1 Regulates Myelin Integrity and Social Behavior via Oligodendrocyte Epigenetic and Metabolic Pathways in a Post-Weaning Social Isolation Model” Translational Psychiatry (IF 7.5, 5.6%), 2026
Park, M., … Lee, G.# “Short-term ketogenic diet induces systemic lipidomic remodeling associated with metabolic adaptation in humans” Frontiers in Nutrition, 2026
Kim, M.,...,Lee, G.#, Jung, S.,# "Emerging Roles of Phospholipid Metabolism in Adipose Tissue Function" Molecules & Cells (IF 8.2, 11.7%), 2026 (*Corresponding author)
Choi, S.,...…Lee, G. ... et al. "Hair growth-promoting activity of ginsenoside Rf from Panax ginseng C.A. Meyer, an industrial crop-derived functional material" Industrial Crops & Products (4.3%), 2026
Choi, YJ., ...Lee, G.#, "Comparative Evaluation of Bovine and Porcine derived Chondroitinon Osteoarthritis Amelioration: A Metabolomics-based Study" The Korean Society of Food Science and Nutrition, 2026
Lee, E., Park, M-Y., Park, M.,..., Ryu, D., Park, D.*, Lee, G.#, Oh, C-M.,# "Inhibition of de novo ceramide synthesis mitigates alpha-synuclein pathology and restores cognitive function in a Parkinson's disease mouse model" npj Parkinson's Disease (IF 8.5, 5.9%), 2026 (*Corresponding author)
2025
Zhang, S., Lee, H., Ahn, H.R…Lee, G. ... et al. “Herbal mixture of Platycodon grandiflorum, Cinnamomum cassia, and Asiasarum sieboldii extracts protects against NASH progression via regulation of hepatic steatosis, inflammation, and apoptosis” Phytomedicine (IF 11.3, 1%), July 2025; 145(2025)157077
Lee, G.* et al., “Dynamic Lipidomic Remodeling and Clinical Correlations After Sleeve Gastrectomy in Obese Subjects” Diabetes & Metabolism Journal (IF 8.5, 6.5%), 2025
Jeong, S.Y., Lee, K.H., Kim, S.H., …Lee, G.# and Kim, K.H.# “(aS)-Glucosciadopitysin, a New Biflavonoid Glycoside from the Leaves of Ginkgo biloba and Osteogenic Activity of Bioflavonoids” Plants, January 2025, 14, 261 (*Corresponding author)
2024
Kim, J.H., Kim, H., Park, M., Park, B., …Lee, G.# and Yu, J. S.* “Comparative Metabolic Profiling of Different Raphanus sativus Cultivars and Their Antioxidant and Anti-Inflammatory Activities” Applied Sciences, December 2024, 15, 247
Lim, W., Choi, S., Kim, J., Baek, K., Park, M., Lee, G., Lim, T. “Vine Tea Extract (VTE) Inhibits High-Fat Diet-Induced Adiposity: Evidence of VTE’s Anti-Obesity Effects In Vitro and In Vivo” Molecular Sciences, November 2024, 25,12042
Lee, G.*, Yang, H. O, “Phytotherapeutic BS012 and Its Active Component Ameliorate Allergic Asthma via Inhibition of Th2-Mediated Immune Response and Apoptosis” Biomolecules and Therapeutics, October 2024, 32(6)
Jae Sik Yu, Hee Ju Kim, Yeo Eun Kim, Hyun Ok Yang, Yu-Kyong Shin, Hyunjae Kim, Soyoon Park, Gakyung Lee*, Lipidomic Assessment of the Inhibitory Effect of Standardized Water Extract of Hydrangea serrata (Thunb.) Ser. Leaves during Adipogenesis, Nutrients, May 2024;16;1508
Hyo‑Sun Choi, Joonki Kim, Sang‑Bin Lee, Lijun Zhang, Dowan Kwon, Huynh Nguyen Khanh Tran, Siqi Zhang, Tianqi Huang, Jae Sik Yu, Gakyung Lee et al. Euonymus hamiltonianus Extract Improves Amnesia in APPswe/Tau Transgenic and Scopolamine‑Induced Dementia Models, Molecular Neurobiology, May 2024;
Gakyung Lee* et al., Exploring the Metabolic Effects of a Herbal Remedy of Asarum sieboldii, Platycodon grandiflorum, and Cinnamomum cassia Extracts: Unraveling Its Therapeutic Potential as a Topical Application for Atopic Dermatitis Treatment, Antioxidants(IF 8.2, 6.2%), Apr 2024; 13,563
Huynh Nguyen Khanh Tran, Jae Sik Yu, Tianqi Huang, Gakyung Lee et al., Neuroprotective Effects of Chemical Constituents of Leaves of Euonymus hamiltonianus Wall., Plants, Apr 2024,13,1094
Woo-Jin Sim, Eunjung Lee, Gakyung Lee, Wonchul Lim, Tae-Gyu Lim, Inhibition of Photoaging by Anthocyanin Metabolites Derived from Rose Petal Extract, Molecular Nutrition & Food Research, Feb 2024; 6:e2300611
~2023
Gakyung Lee* et al. Anti-inflammatory effect and metabolic mechanism of BS012, a mixture of Asarum sieboldii, Platycodon grandiflorum, and Cinnamomum cassia extracts, on atopic dermatitis in vivo and in vitro, Phytomedicine (IF 11.3, 1%), Apr 2023; 115:154818
You-jin Choi, Hyo-Seon Yang, Yunfan Zhang, Wonseok Lee, Sung Ho Yun, Yoon Ah Nam, Gakyung Lee, Byung Hwa Jung et al. Intratracheal exposure to polyhexamethylene guanidine phosphate disrupts coordinate regulation of FXR-SHP-mediated cholesterol and bile acid homeostasis in mouse liver, Ecotoxicity and environmental Safety, Dec 2022; 247:114213
Ah-kyung Jang, Md.Mamunur Rashid, Gakyung Lee et al. Metabolites identification for major active components of Agastache rugosa in rat by UPLC-Orbitap-MS: Comparison of the difference between metabolism as a single component and as a component in a multicomponent extract, Journal of Pharmaceutical and Biomedical Analysis, July 2022; 220(2):114976
Kelvin Pieknell, Yanuar Alan Sulistio, Noviana Wulansari, Wahyu Handoko Wibowo Darsono, Mi-Yoon Chang, Ji-Yun Ko, Jong Wook Chang, Min-Jeong Kim, Man Ryul Lee, Sang A. Lee, Hyunbeom Lee, Gakyung Lee et al. LIN28A enhances regenerative capacity of human somatic tissue stem cells via metabolic and mitochondrial reprogramming, Cell death and differentiation (IF 15.4, 7.4%), Sep 2021; 29(3):1-16
Gakyung Lee* et al. Short‑term changes in the serum metabolome after laparoscopic sleeve gastrectomy and Roux‑en‑Y gastric bypass. Metabolomics, Aug 2021; 17(8)
Soo Hyun Lee*, Gakyung Lee*, et al. Employing metabolomic approaches to determine the influence of age on experimental autoimmune encephalomyelitis (EAE), Molecular immunology, Apr 2021; 135:84-94 (*Equal contribution)
Gakyung Lee* et al. Identification of Altered Metabolic Pathways during Disease Progression in EAE Mice via Metabolomics and Lipidomics, Neuroscience, Sep 2019; 416(2019):74-87
Gakyung Lee* et al. Quantitative profiling of bile acids in rat bile using ultrahighperformance liquid chromatography-orbitrap mass spectrometry: Alteration of the bile acid composition with aging, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, July 2016;1031