Il programma

Roberto Improta

"Photophysics and photochemistry of quadruple helices and i-motifs: towards a canon for non-canonical DNA structures"

Gabriele Travagliante

"Interactions between an antiparallel RNA G-quadruplex and achiral porphyrins"

Veronica Remori

"Exploring the conformational diversity of G-quaruplex structures in gene promoters: insights from single-molecule fluorescence resonance energy transfer experiments"

Simona Marzano 

"Structural insights into the interaction of G-quadruplex dna with an anticancer benzimidazole derivative"

Alessio Nocentini

"Design of multi-targeted chemotherapeutics hitting G-quadruplex and cancer-related human carbonic anhydrases"

Marcello Germoglio

"Investigating the role of FANCJ in G-quadruplex DNA metabolism: insights from tumor cell and Caenorhabditis elegans model systems"

Anna Di Porzio

"DNA G-quadruplex structures as key players in chemo-sensitization of melanoma cells to standard chemotherapy"

Michele Ghezzo

"Development of long non-coding RNA-targeting therapeutics for the treatment of melanoma"

Riccardo Rigo

"The landscape of vimentin interactions in the nuclei of human metastatic cancer cells"

Federica Moraca

"Targeting G-quadruplex dna in oncogene promoter regions: drug-repurposing, molecular dynamics and biophysical studies"

Francesco Morena

"Computational designing of ssRNA Aptamers against the SARS-CoV-2 main protease: a comprehensive investigation using molecular dynamics simulation and circular dichroism analysis"

Domenica Musumeci

"Optimization of the performance of the G4-forming aptamers selected as inhibitors of the protein HMGB1"

Alessia Pepe

"From injectable G-hydrogel to the production of nanogels and microgels: characterizing a new drug delivery system"

Attila Tortorella

"Exploring the interaction of G-quadruplex structures with model membranes: a physicochemical study"

Giulia Miglietta

" Proteomics of micronuclei and transcriptional profiles indicate opposite cellular outcomes induced by different by G4 binders"

Simona Pepe

"Cell-cycle phase specific roles of alternative DNA polymerases and r-loops in genome instability by G-quadruplex structures"

Aurane Froux

"A new generation of G-quadruplex binding compounds: From their synthesis to the characterization of their anticancer effects"

Luisa D'Anna

"RNA G-quadruplexes in Sars-CoV2 genome: computational and experimental approaches for the evaluation of the interaction with asymmetric salphen metal complexes"

Aurianne Rainot

"Developing guanine quadruplexes sensors"

Laura Marretta

"G-quadruplex structures in mitochondrial DNA: investigation of interaction with novel ruthenium (II) polypyridyl complexes"

Roberta Rocca

"Virtual screening of natural compounds for discovering anti-HIV agents targeting LTR-III G-quadruplex"

Elisa De Piante

"Distinct and overlapping roles of human RecQ helicases in the recognition of different G-quadruplexes"

Martina Rotondo

"Enhanced G-Quadruplex Ligand Screening exploiting High-Throughput Synchrotron Radiation Circular Dichroism"

Silvia Di Fonzo

"2-Dimensional UV Resonance Raman Spectroscopy of G4: a tool to detect sequence of molecular events upon external variable changes"

Luca Bertini

"Combining ECG Simulations and SAXS to Investigate G4 Multimerization"

Deniz Mostarac

"G-quadruplex multimers in crowded environments: a multiscale computational approach"

Francesco Fontana

"Supramolecular ordering and spontaneous polymerization of 2’,3’-cGMP"

Ilaria Maurizio

"Genome-wide mapping of G-quadruplexes in Mycobacterium tuberculosis genome: new avenues for drug discovery"

Irene Zanin

"Genome-wide mapping of i-motif reveals their association with transcription regulation in live human cells"

Alessio Maria Caramiello

"A SAR study on substituted, core-extended and dyad naphthalene diimide G-quadruplex ligands leading to potent antitrypanosomal agents"

Valentina Pirota

"Selective delivery of G4-ligands: new strategies for potential cancer therapy"

Premio Gian Piero Spada

Tavola Rotonda

"Open questions and perspectives in the G4 world", Jean Louis Mergny, Antonio Randazzo, Concetta Giancola, Giovanni Capranico