Aurora Kinase A Market was valued at USD 1.5 Billion in 2022 and is projected to reach USD 3.2 Billion by 2030, growing at a CAGR of 10.6% from 2024 to 2030.
Introduction
Aurora Kinase A AURKA is a pivotal serine/threonine kinase that plays a crucial role in cell division particularly during mitosis. Its involvement in various cellular processes including spindle assembly chromosome alignment and cytokinesis has made it a significant target in cancer research and therapeutic development. The Aurora Kinase A market encompasses the development production and commercialization of inhibitors and antibodies targeting AURKA offering promising avenues for cancer treatment. This article delves into the key market insights growth trends and future prospects of the Aurora Kinase A market providing a comprehensive overview for stakeholders and industry professionals.
Understanding Aurora Kinase A
Aurora Kinase A is a serine/threonine kinase that is essential for the proper progression of mitosis. It regulates several critical processes including:
Spindle Assembly: Facilitates the formation of the mitotic spindle ensuring accurate chromosome segregation.
Chromosome Alignment: Ensures chromosomes are correctly aligned at the metaphase plate.
Cytokinesis: Plays a role in the final separation of the daughter cells.
Due to its central role in cell division dysregulation of AURKA has been implicated in various cancers making it a prime target for therapeutic interventions.
Market Overview
The Aurora Kinase A market has witnessed significant growth driven by the increasing prevalence of cancer and the demand for targeted therapies. The market is characterized by the development of small molecule inhibitors and monoclonal antibodies aimed at inhibiting AURKA activity. These therapeutic agents are being explored for their potential to halt tumor progression and improve patient outcomes.
Market Size and Growth Projections
According to a report by Wise Guy Reports the Aurora Kinase A market was valued at USD 13.03 billion in 2023 and is projected to reach USD 23.35 billion by 2032 growing at a compound annual growth rate CAGR of 6.69% during the forecast period from 2025 to 2032. This growth is attributed to the rising incidence of cancer advancements in drug development and technological innovations in the field of oncology.
Key Market Drivers
Rising Cancer Incidence: The increasing number of cancer cases globally has heightened the demand for effective and targeted therapies propelling the growth of the Aurora Kinase A market.
Advancements in Drug Development: Continuous research and development efforts have led to the discovery of novel AURKA inhibitors expanding the therapeutic options available for cancer treatment.
Technological Innovations: Innovations in biotechnology and molecular biology techniques such as next generation sequencing and CRISPR have enhanced the understanding of AURKA's role in cancer facilitating the development of targeted therapies.
Favorable Reimbursement Policies: Supportive reimbursement policies in various regions have made cancer treatments more accessible thereby driving market growth.
Market Segmentation
The Aurora Kinase A market can be segmented based on application drug type route of administration end user and product type:
Application:
Cancer
Inflammatory Diseases
Cardiovascular Diseases
Nervous System Disorders
Others
Drug Type:
Small Molecules
Biologics
Others
Route of Administration:
Oral
Intravenous
Subcutaneous
Topical
Others
End User:
Hospitals
Clinics
Pharmacies
Research Institutes
Others
Product Type:
Generic
Branded
Regional Analysis
The Aurora Kinase A market exhibits regional variations influenced by factors such as healthcare infrastructure research and development activities and regulatory environments:
North America: Dominates the market due to advanced healthcare infrastructure significant investment in cancer research and the presence of major pharmaceutical companies. The region accounted for approximately 40% of the global market in 2023 and is projected to grow at a CAGR of 10% reaching a value of $120 million by 2032.
Europe: Holds the second largest market share driven by a strong focus on research and development and increasing government funding for cancer research. Europe accounted for about 30% of the global market in 2023 and is expected to grow at a CAGR of 9% reaching a value of $90 million by 2032.
Asia Pacific: Expected to witness the highest growth rate during the forecast period attributed to the rising prevalence of cancer increasing healthcare expenditure and growing awareness about early diagnosis. The region accounted for approximately 20% of the global market in 2023 and is projected to grow at a CAGR of 12% reaching a value of $60 million by 2032.
Competitive Landscape
The Aurora Kinase A market is highly competitive with several key players involved in the development and commercialization of AURKA inhibitors and antibodies. Notable companies include:
GeneTex
Agrisera Antibodies
Proteintech Group Inc.
EMD Millipore
Boster Biological
R&D Systems
BioTechne R&D Systems
MyBioSource Inc.
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AbbVie Inc
Amgen Inc
Astex Pharmaceuticals
Inc
CASI Pharmaceuticals Inc
Merck & Co.
Inc
Millennium Pharmaceuticals
Inc
Sanofi
Sareum Holdings Plc
Sigma-Tau S.p.A.
Taiho Pharmaceutical Co.
Ltd.
Vertex Pharmaceuticals Incrporated
Vichem Chemie Research Ltd.
By the year 2030, the scale for growth in the market research industry is reported to be above 120 billion which further indicates its projected compound annual growth rate (CAGR), of more than 5.8% from 2023 to 2030. There have also been disruptions in the industry due to advancements in machine learning, artificial intelligence and data analytics There is predictive analysis and real time information about consumers which such technologies provide to the companies enabling them to make better and precise decisions. The Asia-Pacific region is expected to be a key driver of growth, accounting for more than 35% of total revenue growth. In addition, new innovative techniques such as mobile surveys, social listening, and online panels, which emphasize speed, precision, and customization, are also transforming this particular sector.
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Growing demand for below applications around the world has had a direct impact on the growth of the Global Aurora Kinase A Market
Ovarian Cancer
Anaplastic Large Cell Lymphoma
Brain Tumor
Others
Based on Types the Market is categorized into Below types that held the largest Aurora Kinase A market share In 2023.
AMG-900
Danusertib
ENMD-2076
Ilorasertib
Others
Global (United States, Global and Mexico)
Europe (Germany, UK, France, Italy, Russia, Turkey, etc.)
Asia-Pacific (China, Japan, Korea, India, Australia, Indonesia, Thailand, Philippines, Malaysia and Vietnam)
South America (Brazil, Argentina, Columbia, etc.)
Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)
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1. Introduction of the Global Aurora Kinase A Market
Overview of the Market
Scope of Report
Assumptions
2. Executive Summary
3. Research Methodology of Verified Market Reports
Data Mining
Validation
Primary Interviews
List of Data Sources
4. Global Aurora Kinase A Market Outlook
Overview
Market Dynamics
Drivers
Restraints
Opportunities
Porters Five Force Model
Value Chain Analysis
5. Global Aurora Kinase A Market, By Type
6. Global Aurora Kinase A Market, By Application
7. Global Aurora Kinase A Market, By Geography
Global
Europe
Asia Pacific
Rest of the World
8. Global Aurora Kinase A Market Competitive Landscape
Overview
Company Market Ranking
Key Development Strategies
9. Company Profiles
10. Appendix
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