In a patient with blood in the stools who is hemodynamically stable, use history to differentiate upper vs. lower GI bleed as the investigation differs
In a patient with suspected blood in the stool, explore other possible causes (e.g., beet ingestion, iron, Pepto-Bismol) before doing extensive investigation
Look for patients at higher risk for GI bleed (e.g. previous bleed, ICU admission, NSAIDs, alcohol) so as to modify treatment to reduce risk of GI bleed (e.g. cytoprotection)
In a patient with obvious GI bleeding, identify patients who may require timely treatment even though they are not yet in shock
In a stable patient with lower GI bleeding, look for serious cause (e.g., malignancy, inflammatory bowel disease, ulcer, varices) even when there is an apparent obvious cause for the bleeding (e.g., do not attribute a rectal bleed to hemorrhoids or to oral anticoagulation).
In a patient with an upper GI bleed;
Include variceal bleeding in your differential,
Use the history and physical exam to assess the likelihood of a variceal bleed as its management differs.
Upper GI Bleed
Presentation
Commonly present with hematemesis and/or melena
Frankly bloody emesis suggests more severe bleeding (coffee-ground likely more limited)
Hemodynamic instability or active bleeding should be in monitored setting
Melenic stool on exam [LR 25]
Blood or coffee-ground during nasogastric lavage [LR 9.6]