Through history and/or physical examination, assess the hemodynamic stability of patients with epistaxis.
While attending to active nose bleeds, recognize and manage excessive anxiety in the patient and accompanying family.
In a patient with an active or recent nosebleed, obtain a focused history to identify possible etiologies (e.g., recent trauma, recent respiratory tract infection, medications).
In a patient with an active or recent nosebleed:
Look for and identify anterior bleeding sites
Stop the bleeding with appropriate methods.
In a patient with ongoing or recurrent bleeding in spite of treatment, consider a posterior bleeding site.
In a patient with a nosebleed, obtain lab work only for specific indications (e.g., unstable patient, suspicion of a bleeding diathesis, use of anticoagulation).
In a patient with a nose bleed, provide thorough aftercare instructions (e.g., how to stop a subsequent nose bleed, when to return, humidification, etc.)
Most (90%) anterior bleed from Kiesselbach's plexus/Little's Area (internal/external carotid)
Posterior bleeds from posterolateral branches of sphenopalatine artery
Local trauma (Picking, foreign body, infection, allergic rhinitis)
Environmental (Dry)
Iatrogenic (NG tube)
Medicine (Topical steroids, antihistamines, anticoagulants)
Cocaine
Coagulopathies (platelet disorders, vW disease, hemophilia)
Vascular abnormalities (hereditary hemorrhagic telangiectasia [Osler-Weber-Rendu], carotid artery aneurysm)
Neoplasm (nasal neoplasm)
Note: Hypertension controversial
Trauma (r/o fracture)
Bleeding history (including previous epistaxis and management)
Medication (anticoagulants, nasal sprays/medication), Drugs (cocaine)
Red flags (neopastic)
Headache, facial pain/swelling, nasal blockage, rhinorrhea, anosmia, otalgia, loose teeth
Comfort in calm, quiet area to decrease anxiety
Position sitting forward, mouth open
Pressure by pinching (soft cartilaginous) anterior nose for 15-20mins (nasal ala against septum)
Consider ice pack to nape of neck for reflex vasoconstriction (weak evidence - expert opinion)
If stabilized, consider topical antiseptic ointment up to two weeks
ABC, Vitals
Consider definitive airway, fluid resuscitation
Consider labs if unstable or suspect coagulopathy: CBC, INR, Blood type, cross match, consider LFT/creat
Consider wearing gown, gloves, mask, face shield
Suction (Blow nose to remove clots or use angled Frazier 10-12F suction)
Vasoconstriction
Topical or soaked cotton vasoconstrictors x 5-10 mins (eg. lidocaine, phenylephrine, epinephrine, oxymetazoline, xylometazoline)
Consider Tranexamic acid through atomizer and 15 minutes of external compression
Cautery if bleeding source visible by nasal speculum
Suction and dry prior
Silver nitrate until gray precipitate
Only cauterize one side of septum (if both sides cauterized - risk of perforation)
Electrocautery usually done by ENT after local anesthesia
Packing
Anterior packing (traditional vaseline gauze, compressed sponge/tampon, balloon, absorbable materials)
Admission/ENT consult if bilateral packing needed
Posterior packing (posterior source suggested in failure to visualize anterior source, bleeding from both nares, and blood in posterior pharynx)
Analgesia
Double balloon catheters or foley with 30mL balloon
Admission to monitor for hypoxia
Leave packing 1-3 days prior to removal, can consider prophylactic antistaphylococcal antbiotics to prevent Toxic Shock Syndrome
Consider F/U ENT 48-72h
Consider coagulopathy
Refer to ENT/surgery for endoscopic ligation/embolization in severe cases
Avoid activities
Blowing/picking nose
Open mouth when sneezing
Heavy lifting/strenuous exercise
Drinking alcohol/hot drinks
Stop smoking/alcohol/cocaine
Nose care
Humidifier
Water-based lubricating gel (eg. Secaris) gently applied by Q-tip TID x 10d for dryness
Note: Inhaling petroleum jelly for prolonged periods can potentially cause lung inflammation (lipoid pneumonia)
Consider (low evidence) topical antibacterial (mupirocin) or bacteriostatic (bacitracin) ointment
Direct nasal sprays away from septum
Consider holding aspirin/antiplatelets x 6 days, NSAIDs x 3 days
References:
Ann Emerg Med 2019. Tranexamic Acid. https://www.ncbi.nlm.nih.gov/pubmed/31080025
Guthrie K. http://lifeinthefastlane.com/epistaxis/
The Royal Children's Hospital Melbourne. Epistaxis. http://www.rch.org.au/clinicalguide/guideline_index/Epistaxis/
Yai S. An update on epistaxis. Sept 2015. http://www.racgp.org.au/afp/2015/september/an-update-on-epistaxis
Kucik CJ, Clenney T. Management of Epistaxis. Am Fam Physician. 2005 Jan 15;71(2):305-311. http://www.aafp.org/afp/2005/0115/p305.html