HoloMIT 2.0 is a key enabler for the next generation of the Metaverse, providing interactive and collaborative multi-user holoportation (that is, holographic teleportation) benchmark services, through volumetric and photorealistic representation of users, over 5G and 6G environments. On the one hand, the project will contribute with a modular and adaptive end-to-end platform, potentially offered as Software-as-a-Service (SaaS), taking advantage of the possibilities offered by the cloud continuum and programmatic network architectures and elastic infrastructures to increase the performance, adaptability, and scalability of holoportation services. On the other hand, the project will contribute with accessible multimodal interaction functionalities in order to enable truly interactive and collaborative multi-user holoportation services in a variety of use cases (e.g. training, culture, corporate meetings, gamification), to be selected for through user-centric activities. The anticipated technological contributions will be compatible with existing infrastructures and equipment, as well as be based on compatible extensions to existing standards, in terms of technologies, platforms, protocols and formats. This will increase the possibilities of adoption and effective deployment, avoiding incompatibility problems and also enabling the adoption of additional contributions and/or improvements by third parties. Likewise, the contributions of the project will be evaluated, validated and demonstrated in a variety of pilot actions in 5G environments and beyond, taking advantage of proprietary network and processing infrastructure. In essence, HoloMIT 2.0 will provide contributions beyond the state-of-the-art in the fields of communication networks and immersive technologies, with high potential in different verticals, and bringing economic, social, and sustainability impact.