Neuroscience research has extended our understanding of how early attachment experiences affect brain development and may become reactivated in times of challenge, such as illness and bereavement. Professional caregivers have their own early childhood attachment experiences, which may also become activated. Empathy and compassion are crucial in professional caregivers. This presentation explores how the early and later attachment experiences of professional caregivers may leave them more open to empathic strain and empathic distress in the care of the bereaved. The presentation will also discuss interventions that are proving to be of help in developing compassionate practitioners.