Our research on precision medicine aims to identify biomarkers that are highly specific to individual disease subtypes and patient profiles. By integrating proteomics data and chemical biology tools, we discover biomarkers that not only detect disease but also predict treatment response. These precision biomarkers are essential tools for advancing diagnostics and guiding targeted therapies.

Our lab focuses on advancing drug discovery through a biomarker-driven approach. By uncovering molecular signatures that reflect disease mechanisms, we identify promising therapeutic targets and predictive biomarkers that guide drug discovery. This strategy not only accelerates the drug discovery pipeline but also supports the development of more effective and individualized drug discovery.

Our lab explores the clinical potential of extracellular vesicles (EVs), nanoscale particles that mediate cell-to-cell communication. By harnessing the power of chemical biology tools, such as small molecules, chemical bioprobes, and bioorthogonal chemistry, we investigate and manipulate the EV biogenesis, molecular cargo loading, and intercellular delivery.  Our research aims not only to investigate EVs as precision biomarker, but also to leverage them as therapeutic target themselves in various disease contexts.