Publication

For a full list of publications, visit Google Scholar here

• Jo, A.†,*, Lee, S.†, Lim, W., Kim, M., Park, W.S., Choi, Y-H., Chung, J., Lee, H.H.*, Park, J.*
  Comprehensive validation of inflammatory and kidney injury biomarkers in urinary extracellular vesicles for noninvasive diagnosis of renal cell carcinoma.
  Sumitted († equal contribution)

(30) Lim, J., Lee, S., Hong, Y-S., Choi, J.H., Jo, A., Kang, J.L., Song, T-J., Choi, Y-H.
Nectoric cells alter IRE1a-XBP1 signaling and induce transcriptional changes in glioblastoma
International Journal of Molecular Sciences (2026) 27(1), 474


(29) Choi, Y., Park, J.H., Jo, A., Lim, C.W., Park, J.M., Hwang, J.W., Lee, K.S., Kim, Y.S., Lee, H., Moon, J.*
Blood-derived APLP1+ extracellular vesicles are potential biomarkers for the early diagnosis of brain diseases.
Science Advances (2025) 11(1), eado6894

(28) Yim, J., Park, J., Kim, G., Jo, A.*, Koh, M.* Park, J.*

Conditional PROTAC: Recent Strategies for Modulating Targeted Protein Degradation.

ChemMedChem (2024) 19(22), e202400326.

(27) Cheong, J.†, Jo, A.†, Lee, J., Lee, S., Lee, J., Lee, J.H., Lee H.*, Cheon, J.*

Engineered nanoparticles for clinical assays.

Nature Reviews Bioengineering (2024) 2, 887-905. († equal contribution)

(26) Lin, M., Lee, J., Kim, Y., Kim, G., Jung, Y., Jo, A., Park, M., Lee, S., Lah, J.D., Park, J., Noh, K., Lee, J., Kwak, M., Lungerich, D.*, Cheon, J.*

A Magnetically Powered Nanomachine with a DNA Clutch.

Nature Nanotechnology (2024) 19, 646-651.

(25) Lim, W.†, Lee, S.†, Koh, M.*, Jo, A.*, Park, J.*

Recent advances in chemical biology tools for protein and RNA profiling of extracellular vesicles.

RSC Chemical Biology (2024) 5, 483-499. († equal contribution)

# Featured as Front Cover Article

(24) Jo, A., Green, A., Medina, J.E., Iyer, S., Ohman, A.W., McCerthy, E.T., Reinhardt, F., Gerton, T., Demehin, D., Mishra, R., Kolin, D.L., Zheng, H., Cheon, J., Crum, C.P., Weinberg, R.A., Reuda, B.R., Castro, C.M. *, Dinulescu, D.M. *, Lee, H. *

Inaugurating High-Throughput Profiling of Extracellular Vesicles for Earlier Ovarian Cancer Detection.

Advanced Science (2023) e2301930.

# Featured as Front Cover Article

(23) Park, J. †, Park, JS. †, Huang, CH., Jo, A., Cook, K., Wang, R., Lin, HY., Van Deun, J., Li, H., Min, J., Wang, L., Yoon, G., Carter, BS., Balaj, L., Choi, GS., Castro, CM., Weissleder, R., Lee, H.

An integrated magneto-electrochemical device for the rapid profiling of tumour extracellular vesicles from blood plasma.

Nature Biomedical Engineering (2021) 5(7), 678-689.

(22) Jo, A.†, Kim, M†., Kim, J., Ha, J., Hwang, Y.S., Nam, H., Hwang, I., Kim, J.B., Park, S.B.

Phenotypic discovery of SB1501, an anti-obesity agent, through modulating mitochondrial activities.

ChemMedChem, (2021) 16(7), 1104–1115. († equal contribution)

(21) Ortiz-Orruño, U., Jo, A., Lee, H., van Hulst, N.F., Liebel, M.

Precise nanosizing with high dynamic range holography.

Nano Letters (2021) 21(1), 317–322.

(20) Liebel, M., Arroyo, J.O., Beltrán, V.S., Osmond, J., Jo, A., Lee, H., Quidant, R., Van Hulst, N.F.

3D tracking of extracellular vesicles by holographic fluorescence imaging.

Science Advances (2020) 6(45), eabc2508.

(19) Chand, S., Jo, A., Vellichirammal, N.N., Gowen, A., Guda, C., Schaal, V., Odegaard, K., Lee, H., Pendyala, G., Yelamanchili, S.V.

Comprehensive characterization of nanosized extracellular vesicles from central and peripheral organs: implications for preclinical and clinical applications.

ACS Applied Nano Materials (2020) 3(9), 8906–8919.

(18) Van Deun, J., Jo, A.†, Li, H.†, Lin, HY., Weissleder, R., Im, H., Lee, H.

Integrated dual-mode chromatography to enrich extracellular vesicles from plasma.

Advanced Biosystems (2020) 4(12), e1900310. († equal contribution)

(17) Gyuris, A.†, Navarrete-Perea, J.†, Jo, A., Cristea, S., Zhou, S, Fraser, K, Wei, Z, Krichevsky, A.M., Weissleder, M., Lee, H., Gygi, S.P., Charest, A.

Physical and molecular landscapes of mouse glioma extracellular vesicles define heterogeneity.

Cell Reports (2019) 27(13), 3972–3987.e6.

(16) Bae, SH. †, Jo, A.†, Park J.H., Lim, CW., Choi, Y., Oh, J., Park, JM., Kong, T., Weissleder, R., Lee, H.*, Moon J.*

Bioassay for monitoring the anti-aging effect of cord blood treatment.

Theranostics (2019) 9(1), 1–10. († equal contribution)

(15) Fraser, K., Jo, A., Giedt, J., Vinegoni, C., Yang, K., Peruzzi, P., Chiocca, E. A., Breakefield, X.O., Lee, H., Weissleder, R.

Characterization of single microvesicles in plasma from glioblastoma patients.

Neuro-Oncology (2019) 21(5), 606–615.

(14) Kim, H., Jo, A., Choi, S., Nam, H., Byun, W.G., Bae, H., Choi, J.H., Park, S.B.

Rational design and synthesis of reversible covalent PPARγ antagonistic ligands inhibiting Ser273 phosphorylation.

Asian Journal of Organic Chemistry (2019) 8, 1698-1706.

(13) Jo, A.†, Sung, J.†, Lee, S., Nam, H., Lee, H.W., Park, J., Kim, H.M., Kim, E., Park, S.B.

Near-IR fluorescent tracer for glucose-uptake monitoring in live cells.

Bioconjugate Chemistry (2018) 29(10), 3394–3401. († equal contribution)

(12) Kim, H., Jo, A., Ha, J., Lee, Y., Hwang, Y.S., and Park, S.B.

Pyrazolo[1,5-a]pyridine-Fused pyrimidine based novel fluorophore and its bioapplication to probing lipid droplets.

Chemical Communications (2016) 52(50), 7822–7825.

(11) Bae, H., Jang, J.Y., Choi, S.-S., Kim, H., Jo, A., Choi, J.H., Suh, S.W., and Park, S.B.

Mechanistic elucidation guided by covalent inhibitors for the development of anti-diabetic PPARγ ligands.

Chemical Science (2016) 7(8), 5523–5529.

(10) Jo, A.†, Jung, J. †, Kim, E., and Park, S.B.

A high-content screening platform with fluorescent chemical probes for discovery of first-in-class therapeutics.

Chemical Communications (2016) 52(47), 7433–7445. († equal contribution)

# Invited Feature Article

(9) Choi, S., Kim, E.-S., Jung, J.-E., Marciano, D., Jo, A., Koo, J.Y., Choi, Y.C., Yang, Y.R., Jang, H.-J., Kim, E.-K., Kwon, H.M., Lee, I.H., Park, S.B., Suh, P.-G., Griffin, P.R., and Choi, J.H.

PPARγ ligand gleevec improves insulin sensitivity and promotes the browning of white adipose tissue.

Diabetes (2016) 65(4), 829–839.

(8) Lee, Y., Jo, A., and Park, S.B.

Rational improvement of molar absorptivity guided by oscillator strength: a case study with furoindolizine-based core skeleton.

Angewandte Chemie International Edition (2015) 54(52),15689–15693.

(7) Kim, J.I., Huh, J.Y., Sohn, J.H., Choe, S.S., Lee, Y.S., Lim, C.Y., Jo, A., Park, S.B., Han, W., and Kim, J.B.

Lipid-overloaded enlarged adipocytes provoke insulin resistance independent of inflammation.

Molecular and Cellular Biology (2015) 35(10),1686–1699.

(6) Park, J., Um, J.I., Jo, A., Lee, J., Jung, D.-W., Williams, D., and Park, S. B.

Impact of molecular charge on GLUT-specific cellular uptake of glucose bioprobes and in vivo application of the glucose bioprobe, GB2-Cy3.

Chemical Communications (2014) 50(66), 9251–9254.

# Featured as Front Cover Article

(5) Koh, M., Park, J., Koo, J.Y., Lim, D., Cha, M.Y., Jo, A., Choi, J.H., and Park, S. B.

Phenotypic screening to identify small-Molecule enhancers for glucose uptake: target identification and rational optimization of their efficacy.

Angewandte Chemie International Edition (2014) 53(20), 5102–5106.

# Featured as Front Cover Article

(4) Choi, E., Kim, E., Lee, Y., Jo, A., and Park, S. B.

Rational perturbation of fluorescence quantum yields in emission-tunable and predictable fluorophores, Seoul-Fluors, via facile synthesis using C-H activation

Angewandte Chemie International Edition (2014) 53(5), 1346–1350.

(3) Jo, A., Park, J., and Park, S.B.

Exploiting the mechanism of cellular glucose uptake to develop an image-based high-throughput screening system in living cells

Chemical Communications (2013) 49(45), 5138–5140.

# Features as Back Cover Article

(2) Lee, S., Jo, A., and Park, S.B.

Discovery of highly selective FLT3 kinase inhibitor from phenotypic cell viability profiling.

MedChemComm (2013) 4(1), 228–232.

# Featured as Front Cover Article

# Invited for the themed issue highlighting “New Talent” in Medicinal Chemistry

(1) Lee, D.-N., Jo, A., Park, S.B., and Hong, J.-I.

Colorimetric and orange light-emitting fluorescent probe for pyrophosphate in water.

Tetrahedron Letters (2012) 53(41), 5528–5530.