We work at the interface of Evolutionary Biophysics (molecular/protein evolution) and Systems Biology. We are interested in understanding how protein molecules evolve and how that shapes the systems-scale evolvability landscape. We focus on a range of disease biology questions and develop and deploy our evolution-informed strategies to answer them.

News and Recent Updates 

September 2026- 

A. Shivram's paper 'DELTA: A Gain-Loss Decomposition Framework for Interpretable Protein Stability Prediction' gets selected at the 24th Asia Pacific Bioinformatics Conference, Taiwan.