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Dr. E. Srinivasan 

Post-Doctoral Fellow 

Molecular Biophysics Unit (MBU)

Indian Institute of Science

Bengaluru, Karnataka, India

நோய்நாடி நோய்முதல் நாடி அதுதணிக்கும்

வாய்நாடி வாய்ப்பச் செயல். - திருவள்ளுவர்

Educational Qualification

Ph.D.  @ VIT (Deemed to be University), Vellore, Tamilnadu, India (Advisor- Prof. R. Rajasekaran)

M.S (by Research) in Computational Biology @ VIT (Deemed to be University), Vellore, Tamilnadu, India(Advisor- Prof. R. Rajasekaran)

B.Tech (Biotechnology, 2014) from Adhiyamaan College of Engineering (Autonomous), Hosur, Tamilnadu, India.

Selected Publications 

Srinivasan, E., & Rajasekaran, R. (2018). Deciphering the loss of metal binding due to mutation D83G of human SOD1 protein causing FALS disease. International Journal of Biological Macromolecules, 107(PartA), 521–529. 

E. Srinivasan, R. Rajasekaran: Exploring the cause of aggregation and reduced Zn binding affinity by G85R mutation in SOD1 rendering Amyotrophic lateral sclerosis: In silico study on SOD1 mutant G85R. Proteins Structure Function and Bioinformatics, DOI:10.1002/prot.25288

E. Srinivasan, R. Rajasekaran: Computational investigation of curcumin, a natural polyphenol that inhibits the destabilization and the aggregation of human SOD1 mutant (Ala4Val). RSC Advances, 6(104):102744-102753., DOI:10.1039/C6RA21927F

E. Srinivasan, R. Rajasekaran: Computational simulation analysis on human SOD1 mutant (H80R) exposes the structural destabilization and the deviation of Zn binding that directs familial amyotrophic lateral sclerosis. Journal of Biomolecular Structure & Dynamics. 

Professional honours