Publications

Chambers, C., Quan, L., Yi, G., and Esquela-Kerscher, A. (2022) CRISPR gene editing tool for microRNA cluster network analysis. J. Vis. Exp. (182), e63704, April 25, 2022 doi:10.3791/63704.

Liyanage, T., Alharbi, B., Quan, L., Esquela-Kerscher, A., and Slaughter, G. (2022). Plasmonic-Based Biosensor for the Early Diagnosis of Prostate Cancer. ACS Omega 2022 Jan5;7(2):2411-2418. PMCID: PMC8771705.

Yin, R., Song, J., Esquela-Kerscher, A., and Kerscher, O. (2021) Detection of Rapidly Accumulating Stress-Induced SUMO in Prostate Cancer Cells by a Fluorescent SUMO Biosensor. Mol Carcinog. 2021 Dec;60(12):886-897. doi: 10.1002/mc.23353. Epub 2021 Sep 24. PMID: 34559929.

Cadieux, Z., Lewis, H., Esquela-Kerscher A. (2019) ‘Chapter 1. Role of nutritional epigenomics and microRNAs in pathogenesis of cancer’ in Peplow, P., Martinez, B., Calin, G., Esquela-Kerscher, A. (eds.) MicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets. Royal Society Chemistry, pp. 1–35.

Pons, M., Koniaris, L., Moe, S., Gutierrez, J., Esquela-Kerscher, A., and Zimmers, T. (2018) GDF11 induces kidney fibrosis, renal cell epithelial-to-mesenchymal transition and kidney dysfunction and failure. Surgery. In Press. (*Collaboration with Dr. Teresa Zimmers' group, Indiana University School of Medicine)

Hasegawa, T., Glavich, G., Pahuski, M., Short, A.M., Semmes, O.J., Yang, L., Galkin, V., Drake, R.R., Esquela-Kerscher, A. (2018) Characterization and evidence of the miR-888 cluster as a novel cancer network in prostate. Molecular Cancer Research Apr;16(4):669-681. doi: 10.1158/1541-7786.MCR-17-0321. Epub 2018 Jan 12. *This article is featured in the Highlights section of this journal.

Hasegawa, T., Lewis, H. and Esquela-Kerscher, A. (2017) ‘The role of non-coding RNAs in prostate cancer’, in Laurence, J. (ed.) Translating MicroRNAs to the Clinic. Elsevier Inc., pp. 329–369.

Esquela-Kerscher, A., Krishna, N.K., Catalano, J.B., Lundberg, P.S. and Kerry, J.A. (2016) Design and Effectiveness of Self-Directed Interactive Learning Modules Based on PowerPoint. Medical Science Educator 2016;26(1):69–76.

Lewis, H. and Esquela-Kerscher, A. (2015) ‘MicroRNA epigenetic systems and cancer’, in Thiagalingam, S. (ed.) Systems Biology of Cancer. Cambridge: Cambridge University Press, pp. 134–153.

Esquela-Kerscher, A. (2014) The lin-4 microRNA: the ultimate micromanager. News & Views for Cell Cycle, Feb 28;13(7).

Lewis, H. Lance, R., Troyer, D., Beydoun, H., Hadley, M., Orians, J., Benzine, T., Madric, K., Semmes, J., Drake, R., Esquela-Kerscher, A. (2014) miR-888 is an expressed prostatic secretions-derived microRNA that promotes prostate cell growth and migration. Cell Cycle 2014 Jan 15;13(2):227-39. *This article is featured in the News & Views section of this journal.

Allen, J.D. and Esquela-Kerscher, A. (2013) Gongylonema pulchrum infection in a resident of Williamsburg, Virginia verified by genetic analysis. American Journal of Tropical Medicine & Hygiene, Oct;89(4):755-7. (*Collaboration with Dr. Jonathan Allen, The College of WIlliam & Mary)

Lewis, H. & Esquela-Kerscher, A. (2012) The let-7 microRNA family: Big roles in development and disease. Frontiers in Research Articles Series, Nature Education/Bedford Freeman Worth.

Jo, J & Esquela-Kerscher, A. (2011). A growing molecular toolbox for the functional analysis of microRNAs in Caenorhabditis elegans. Briefings in Functional Genomics. Jul;10(4):175-80.2011.

Cazares LH, Drake RR, Esquela-Kirscher A, Lance RS, Semmes OJ, Troyer DA. (2011) Molecular pathology of prostate cancer. Cancer Biomark. 9(1-6):441-59. (Note name misspelled at time of publication).

Esquela-Kerscher, A. (2010) ‘MicroRNAs function as tumor suppressor genes and oncogenes’, in Slack, F. (ed.) MicroRNAs in Development and Cancer. Imperial College Press, pp. 149-184.

Breving, K. & Esquela-Kerscher, A. (2010). The Complexities of MicroRNA Regulation: mirandering around the rules. Int J Biochem Cell Biol. 42, 1316-1329.

Kato, M., Paranjape, T., Ullrich, R., Nallur, S., Gillespie, E., Keane, K., Esquela-Kerscher, A., Weidhaas, J.B., and Slack, F.J. (2009). The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human cells. Oncogene 2009 Jun 25;28(25):2419-24.

Weidhaas, J.B.*, Esquela-Kerscher, A.*, Ratner, E., Slack, F.J. MicroRNA Detection and Profiling. Book chapter in Methods in Molecular Biology. The Humana Press Inc. 2008. (*These authors contributed equally to this work.)

Esquela-Kerscher, A, Trang, P, Wiggins, J.F., Patrawala, L., Cheng, A., Ford, L., Weidhaas, J.B., Brown, D., Bader, A.G., Slack, F.J. (2008). The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle Mar 15;7(6):759-64.

Johnson, C.D.*, Esquela-Kerscher, A.*, Stefani, G.*, Byrom, M., Kelnar, K., Ovcharenko, D., Wilson, M., Wang, X., Shelton, J., Shingara, J., Chin, L., Brown, D., Slack, F.J. (2007). The let-7 MicroRNA Represses Cell Proliferation Pathways in Human Cells. Cancer Res 15; 67(16):7713-22. (*These authors contributed equally to this work.)

Esquela-Kerscher, A., and Slack, F.J. (2006). Oncomirs – MicroRNAs with a role in cancer. Nature Reviews Cancer 6, 259-269.

Esquela-Kerscher, A., Johnson, S.M., Bai, L., Saito, K., Partridge, J., Reinert, K., and Slack, F.J. (2005). Post-embryonic expression of C. elegans microRNAs belonging to the lin-4 and let-7 families in the hypodermis and reproductive system. Dev Dyn 234, 868-877.

Schulman, B., Esquela-Kerscher, A., Slack, F.J. (2005). Temporal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Dev Dyn 234, 1046-1054.

Zimmers, T.A., Jin, X., Hsiao, E.C., McGrath, S.A., Esquela, A.F., Koniaris, L.G (2005). Growth differentiation factor-15/macrophage inhibitory cytokine-1 induction after kidney and lung injury. Shock 23(6), 543-548.

Esquela-Kerscher, A., and Slack, F.J. (2004). The age of high-throughput microRNA profiling. Nature Meth 1, 106-107.

Esquela, A.F. and Lee, S.-J. (2003). Regulation of metanephric kidney development by growth/differentiation factor 11. Dev Biol 257, 356-370. (Esquela, A.F. - corresponding author)

Zimmers, T.A., Davies, M.V., Koniaris, L.G., Haynes, P., Esquela, A.F., Tomkinson, K.N., McPherron, A.C., Wolfman, N.M., and Lee S.-J. (2002). Induction of cachexia in mice by systemically administered myostatin. Science 296, 1486-1488.

Esquela, A.F., Zimmers, T.A., Koniaris, L.G., Sitzman, J.V., and Lee, S.-J. (1997). Transient down-regulation of Inhibin ßC following partial hepatectomy. Biochem Biophys Res Commun 235, 553-556.

McGrath, S.A., Esquela, A.F., and Lee, S.-J. (1995). Oocyte-specific expression of growth/differentiation factor-9. Mol Endocrinol 9,131-136.