Banerjee, S.; Gupta, S. K.; Pal, S.; Prabhakaran, E. N., Crystal structures reveal that the sterically hindered pivaloyl‐cisProlyl amide bond is energetically frustrated. Peptide Sci. 2024, (DOI: 10.1002/pep2.24337).
Banerjee, S.; Gupta, S. K.; Prabhakaran, E. N., Direct Evidence for Synchronicity between Rotation along Cα−C′ and Pyramidalization of C′ in Amides. ChemistrySelect 2023, (DOI: 10.1002/slct.202301105).
Gupta, S. K.; Banerjee, S.; Prabhakaran, E. N., van der Waals interactions to control amide cis–trans isomerism. New J. Chem. 2022, (DOI: 10.1039/D2NJ01457B).
Gupta, S. K.; Banerjee, S.; Prabhakaran, E. N., Understanding the anomaly of cis–trans isomerism in Pro-His sequence. Bioorg. Med. Chem. Lett. 2022, (DOI: 10.1016/j.bmcl.2022.128985).
Pal, S.; Banerjee, S., Prabhakaran, E. N., α-Helices propagating from stable nucleators exhibit unconventional thermal folding. FEBS Lett. 2021, (DOI:10.1002/1873-3468.14216).
Prabhakaran E.N., Reddy D.N., Banerjee S., A kinetic method for detecting intramolecular peptide H-bonds. New J. Chem. 2021, (DOI: 10.1039/D1NJ03544D).
Prabhakaran E.N., Pal S., Kumar A., Mahajan S., Large Scale Synthesis of Native Turn and Helix Mimics Stabilized by a Generic Hydrogen Bond Surrogate. Protocol Exchange, 2021, (DOI: 10.21203/rs.3.pex-1537/v1).
Reddy, S. S., Pal, S.; Ghosh, S., Prabhakaran, E. N., Hydrogen Bond Surrogate‐Constrained Dynamic Anti‐parallel β‐Sheets. ChemBioChem. 2021, 22, 2111–2115.
Pal, S., Prabhakaran, E. N., Trimodular solution phase protocol for rapid large-scale synthesis of hydrogen bond surrogate-constrained α-helicomimics. Eur. J. Org. Chem. 2021, 1714 – 1719.
Pal, S.; Banerjee, S., Prabhakaran, E. N., Helix-Coil Transition at a glycine following a nascent α-helix: A synergetic guidance mechanism for helix growth. J. Phys. Chem. A. 2020, 124, 7478–7490.
Pal S; Banerjee, S., Kumar A, Prabhakaran, E.N., H-Bond Surrogate-Stabilized Shortest Single-Turn α-Helices: sp2 Constraints and Residue Preferences for the Highest α-Helicities. ACS Omega. 2020, 5, 13902-13912.
Prabhakaran, E. N., Tumminakatti, S., Vats K, Ghosh, S. Spectral evidence for generic charge → acceptor interactions in carbamates and esters. RSC Adv.. 2020, 10, 11871-11875.
Pal S, Prabhakaran, E.N., Hydrogen bond surrogate stabilized water soluble 310-helix from a disordered pentapeptide containing coded α-amino acids. Tetrahedron Lett. 2018, 59, 2515-2519.
Vats K, Prabhakaran, E.N., Disallowed conformations of Amino Acids in Proteins and Peptides, Cutting Edge, 2017, 9 -13.
Tumminakatti, S., Khatri, B., Krishnamurthi, V., Athavale, V., Prabhakaran, E. N. Solution Structural Features of N-Acyl Homoserine Lactones. Tetrahedron Letters, 2015, 56, 5771-5775.
Tumminakatti, S., Reddy, D. N., & Prabhakaran, E. N., Exploring the consequences of a representative “disallowed” conformation of Aib on a 310‐helical fold. Peptide Science, 2015, 104, 21-36.
Thirupathi, R., Prabhakaran, E. N., Estimation of the 2.05 helix type i→ i hydrogen bond energy at Aib∗-Oxa motif: an isodesmic approach. Tetrahedron Letters, 2014, 55, 3418-3421.
Thirupathi R., Reddy Y. J., Prabhakaran, E.N., Atreya H. S. Unravelling the chemical origin of debris in Graphene Oxide. J. Chem. Soc. 2014, 55, 3418.
Reddy, D. N., Prabhakaran, E. N. Steric and Electronic Interactions Controlling the cis/trans Isomer Equilibrium at X-Pro Tertiary Amide Motifs in Solution. Biopolymers. 2013, 101(1), 66-77.
Reddy, D. N., George, G., Prabhakaran, E. N. Crystal-Structure Analysis of cis-X-Pro-Containing Peptidomimetics: Understanding the Steric Interactions at cis X-Pro Amide Bonds. Angew. Chem. Int. Ed. Engl. 2013, 52, 3935.
A method for stabilizing the cis prolyl peptide bond: influence of an unusual n→π* interaction in 1,3-oxazine and 1,3-thiazine containing peptidomimetics. Reddy, D. N., Thirupathi, R., Tumminakatti, S., Prabhakaran, E. N. Tet. Lett. 2012, 53, 4413-4417.
Protein-Protein Complexes. Thirupathi, R., Sravanthi, S., Anusha, K., Prabhakaran, E. N. J. Ind. Inst. Sci., 2011, 91(4), 497-520.
Accessing the disallowed conformations of peptides employing amide-to-imidate modification. Reddy, D. N., Thirupathi, R., Prabhakaran, E. N. Chem. Commun., 2011, 47, 9417–9419.
Self-assembled microtubes and rhodamine 6G functionalized Raman-active gold microrods from 1-hydroxybenzotriazole. Thirupathi, R., Prabhakaran, E. N. J. Chem. Sci., 2011, 123(3), 247–254.
Synthesis and Isolation of 5,6-Dihydro-4H-1,3- Oxazine Hydrobromides by Autocyclization of N-(3-Bromopropyl)amides. Reddy, D. N., Prabhakaran, E. N. J. Org. Chem., 2011, 76, 680–683.
N-{1-[(3-Bromopropyl)aminocarbonyl]ethyl}-2-(2-nitrobenzenesulfonamido)propionamide. R. Tirupathy, D. N. Reddy, S. Brinda, E. N. Prabhakaran. Acta Cryst. E(65) 2009, 2308-2309.
Free Radical-Mediated Aryl Amination: Convergent Two- and Three-Component Couplings to Chiral 2,3-Disubstituted Indolines. Rajesh, V.; Smith, C. R.; Prabhakaran, E. N.; Johnston, J. N. J. Org. Chem. 2008, 73(8), 3040-3046.
Protein structure, stability and solubility in water and other solvents. C. Nick Pace; Saul Trevino: Erode Prabhakaran; J. Martin Scholtz., Phil. Trans. R. Soc. Lond. B, 2004, 359 (1448), 1225-1234.
Free Radical-Mediated Aryl Amination: Convergent Two- and Three-Component Couplings to Chiral 2,3-Disubstituted Indolines. Smith, C. R.; Prabhakaran, E. N.; Viswanathan, R.; Johnston J. N. Tetrahedron: Asymmetry 2004, 1-5.
Free Radical-Mediated Aryl Amination and its Use in a Convergent [3+2] Strategy for Enantioselective Indoline α-Amino Acid Synthesis. Viswanathan, Rajesh; Prabhakaran, Erode N.; Plotkin, Michael A.; Johnston, Jeffrey N., J. Am. Chem. Soc., 2003, 125, 163-168.
Free radical-mediated vinyl amination: a mild, general pyrrolidinyl enamine synthesis. Benjamin M. Nugent, Amie L. Williams, E. N. Prabhakaran, and Jeffrey N. Johnston., Tetrahedron, 2003, 59 (45), 8877-8888.
Cobalt-Catalyzed One-Pot Three-Component Coupling Route to β-Acetamido Carbonyl Compounds: A General Synthetic Protocol for γ-Lactams. Rao, I. Nageshwar; Prabhakaran, Erode N.; Das, Saibal Kumar; Iqbal, Javed., J. Org. Chem., 2003, 68 (10), 4079-4082.
Reverse Turn Induced π-Facial Selectivity during Polyaniline-Supported Cobalt(II) Salen Catalyzed Aerobic Epoxidation of N-Cinnamoyl L-Proline Derived Peptides. Nandy, Jyoti P.; Prabhakaran, Erode N.; Kumar, Kiran S.; Kunwar, A.C.; Iqbal, Javed., J. Org. Chem., 2003, 68(5), 1679-1692.
Free Radical Mediated Vinyl Amination: Access to N,N-Dialkyl Enamines and their β-Stannyl and β-Thio Derivatives. Prabhakaran, Erode N.; Nugent, Benjamin M.; Cox, Amie L.; Johnston, Jeffrey N., Org. Lett., 2002, 4(24), 4197-4200.
Synthesis of Small Cyclic Peptides via Reverse Turn Induced Ring Closing Metathesis of Tripeptides. Prabhakaran, Erode N.; Rao, Nageshwara I.; Boruah, Anima; Iqbal, Javed., J. Org. Chem., 2002, 67, 8247-8250.
Synthesis and Conformation of Proline Containing Tripeptides Constrained with Phenylalanine-like Aziridine and Dehydrophenylalanine Residues. Prabhakaran, Erode N.; Nandy, Jyoti N.; Shukla, Shalini; Tiwari, Amit; Das Saibal K.; Iqbal, Javed., Tet. Lett., 2002, 43, 6461-6466.
Nonconventional Carbon Additions to Azomethines. Aryl Amination/Indoline Synthesis by Direct Aryl Radical Addition to Azomethine Nitrogen. Johnston, Jeffrey N.; Plotin, Michael A.; Viswanathan, Rajesh; Prabhakaran, Erode N., Org. Lett., 2001, 3, 1009-1010.
Parallel Synthesis of α-hydroxy β-amino amide containing peptide derivatives as structural analogues of bestatin. Prabhakaran, Erode N.; Rajesh, S.; Reddy, M.; Iqbal, Javed., J. Ind. Inst. Sci. 2001, 81(2), 143-147.
π-Facial Selectivity in Polyaniline Supported Cobalt Catalyzed Aerobic Epoxidation of N-Cinnamoyl Proline Derivatives. Prabhakaran, Erode N.; Nandy, Jyoti P.; Shukla, Shalini; Iqbal, Javed., Tett. Lett., 2001, 42, 333-337.
Synthesis of Cyclic Peptides as Mimics for the Constrained Conformation of Structural Analogues of HIV Protease Inhibitors. Prabhakaran, Erode N.; Viswanathan, Rajesh; Dubey, Shalini; Iqbal, Javed., Tet. Lett., 2001, 42, 339-342.
Polyaniline Supported Cobalt Catalyst: A Three Component Condensation Route to β-Amino Acid Derivatives. Prabhakaran, Erode N.; Iqbal, Javed., J. Org. Chem., 1999, 64, 3339-3341.
Cobalt Catalyzed Synthesis of β-turn Mimics as Model for the Bioactive Conformation of HIV-1 Protease Inhibitors. Iqbal, Javed; Nandy, Jyoti P.; Prabhakaran, Erode N.; Rajesh, Sankar; Krishnan, Shyam., Proc. Int. Con. Org. Synth., 1998, 12, 339-346.