Learning Objectives
Understand the advanced anatomy and physiology of the airway, including differences across age groups
Perform advanced airway management techniques, including endotracheal intubation and alternative airway devices
Recognize and manage airway obstructions and difficult airways using appropriate assessment tools and interventions
Utilize ventilation equipment effectively, including mechanical ventilators and non-invasive ventilation devices
Interpret capnography readings and adjust ventilatory support based on waveform analysis
Apply critical thinking in airway decision-making, considering patient condition, environment, and available resources
Nasal Cavity
Functions: Warming, humidifying, filtering air.
Structures: Nares, septum, turbinates, sinuses.
Oral Cavity
Structures: Lips, teeth, tongue, hard and soft palates.
Importance in airway management: Alternative route for ventilation and intubation.
Pharynx
Nasopharynx: Behind nasal cavity; contains adenoids, Eustachian tube openings.
Oropharynx: Behind oral cavity; includes tonsils, base of tongue.
Laryngopharynx (Hypopharynx) : Extends from hyoid bone to esophagus; pathway for food and air.
Larynx
Functions: Airway protection, phonation.
Cartilages:
Thyroid Cartilage: Prominent "Adam's apple."
Cricoid Cartilage: Only complete cartilaginous ring; landmark for cricothyrotomy.
Epiglottis: Leaf-shaped flap that prevents aspiration during swallowing.
Vocal Cords
Abduction and adduction control airflow and sound production.
Intrinsic Muscles
Control tension and position of vocal cords.
Glottic Opening
Narrowest part of the adult airway.
Trachea
Extends from cricoid cartilage to carina.
Composed of C-shaped cartilaginous rings.
Lined with ciliated epithelium for mucus clearance.
Bronchi and Bronchioles
Mainstem Bronchi: Right is wider, shorter, and more vertical—aspirated objects more likely here.
Lobar and Segmental Bronchi: Branch into each lung lobe.
Bronchioles: Lack cartilage; smooth muscle controls diameter.
Terminal Bronchioles: Lead to alveolar ducts.
Alveoli
Site of gas exchange.
Surfactant reduces surface tension, preventing collapse.
Alveolar-capillary membrane facilitates diffusion of oxygen and carbon dioxide.
Mechanics of Ventilation
Inspiration: Diaphragm contracts, thoracic cavity expands, negative pressure draws air in.
Expiration: Passive process; diaphragm relaxes, positive pressure expels air.
Gas Exchange
Oxygen Transport: Bound to hemoglobin (~98%), dissolved in plasma.
Carbon Dioxide Transport: Dissolved in plasma, as bicarbonate, bound to proteins.
Oxygen-Hemoglobin Dissociation Curve
Factors shifting the curve:
Right Shift: Decreased affinity (↑ temperature, ↑ CO₂, ↑ H⁺, 2,3-DPG).
Left Shift: Increased affinity (↓ temperature, ↓ CO₂, ↓ H⁺).
Age-Related Anatomical Differences
Pediatrics
Larger tongue relative to mouth.
Narrow nasal passages.
Higher, more anterior glottic opening.
Floppier epiglottis.
Narrowest point at cricoid cartilage.
Geriatrics
Decreased lung elasticity.
Increased chest wall rigidity.
Diminished cough reflex.
Mallampati Classification
Classes I-IV based on visibility of oropharyngeal structures.
Class I: Full visibility of tonsils, uvula, and soft palate.
Class IV: Only hard palate visible.
LEMON Law
Look externally: Facial trauma, large incisors, beard, or moustache.
Evaluate 3-3-2 Rule:
3 fingers mouth opening.
3 fingers thyromental distance.
2 fingers distance from hyoid bone to thyroid notch.
Mallampati score.
Obstruction: Obesity, foreign bodies, swelling.
Neck mobility: Limited in trauma or arthritis.
Thyromental Distance
Distance between the thyroid notch and mentum (chin).
Less than 6 cm (three fingerbreadths) may indicate a difficult airway.
Signs of Partial Airway Obstruction
Stridor.
Snoring.
Gurgling.
Hoarseness.
Signs of Complete Airway Obstruction
Inability to speak or cough.
Universal choking sign.
Cyanosis.
Loss of consciousness.
Assessment of Breathing
Rate: Tachypnea, bradypnea, apnea.
Effort: Use of accessory muscles, nasal flaring, retractions.
Pattern: Cheyne-Stokes, Kussmaul respirations.
Skin Color: Pallor, cyanosis.
Airway Patency Check
Look: Chest rise and fall.
Listen: Air movement at mouth and nose.
Feel: Air movement on cheek.
Head-Tilt/Chin-Lift
Contraindicated in suspected cervical spine injury.
Jaw-Thrust Maneuver
Use when cervical spine injury is suspected.
Technique:
Kneel at patient's head.
Place fingers behind angles of mandible.
Lift upward, displacing jaw forward.
Recovery Position
Lateral recumbent to maintain airway in patients with decreased consciousness but adequate breathing.
Oropharyngeal Airway (OPA)
Indications: Unconscious patients without gag reflex.
Contraindications: Conscious patients, intact gag reflex.
Insertion Techniques:
Adults: Insert upside down, rotate 180°.
Pediatrics: Use tongue depressor, insert right side up.
Nasopharyngeal Airway (NPA)
Indications: Semiconscious patients with intact gag reflex.
Contraindications: Basilar skull fracture, nasal trauma.
Insertion Technique:
Lubricate, bevel toward septum, insert into larger nostril.
Equipment
Rigid (Yankauer) and flexible catheters.
Portable suction devices.
Techniques
Pre-oxygenate patient.
Limit suctioning to 10-15 seconds.
Apply suction on withdrawal in a circular motion.
4.1.1 Indications and Contraindications
Indications
Inability to maintain airway patency.
Failure to protect airway (e.g., absent gag reflex).
Failure to ventilate adequately.
Anticipation of clinical deterioration.
Contraindications
Complete airway obstruction (alternative methods required).
Severe facial trauma requiring surgical airway.
4.1.2 Equipment Preparation
Basic Equipment
Laryngoscope handle and blades (Macintosh and Miller).
Endotracheal tubes (ETT) in various sizes.
Stylet.
Syringe (10 mL for cuff inflation).
Suction device.
Bag-valve-mask (BVM) with oxygen source.
End-tidal CO₂ detector (capnography).
Additional Equipment
Magill forceps.
Lubricant.
Tape or securing device.
Alternative airway devices as backup.
4.1.3 Laryngoscope Blades
Macintosh Blade (Curved)
Fits into vallecula.
Lifts epiglottis indirectly.
Miller Blade (Straight)
Directly lifts epiglottis.
Preferred in pediatric patients.
4.1.4 Procedure
Preparation
Ensure all equipment is ready and functioning.
Position patient in "sniffing" position (unless contraindicated).
Pre-oxygenate with 100% oxygen for 3-5 minutes if possible.
Visualization
Open patient's mouth using scissor technique.
Insert laryngoscope blade to the right of the tongue.
Sweep tongue to the left.
Advance blade until epiglottis is visualized.
Identifying Landmarks
Epiglottis: Leaf-shaped structure.
Vocal Cords: Pearly white bands.
Arytenoid Cartilages: Posterior landmarks.
Insertion of Endotracheal Tube
Pass ETT through vocal cords.
Advance tube 2-3 cm beyond cords.
Typical depth: 21 cm at teeth for females, 23 cm for males.
Securing the Tube
Inflate cuff with required air volume (usually 5-10 mL).
Confirm placement before releasing hold on tube.
Secure with tube holder or tape.
4.1.5 Verification of Tube Placement
Primary Methods
Direct Visualization: Seeing tube pass through vocal cords.
Auscultation: Bilateral breath sounds, absence of gastric sounds.
Chest Rise and Fall: Symmetrical movement.
Secondary Methods
End-Tidal CO₂ Detection
Colorimetric Device: Color change indicating CO₂.
Capnography: Waveform provides continuous monitoring.
Condensation in Tube
Troubleshooting
If unilateral breath sounds (right mainstem intubation), withdraw tube 1-2 cm and reassess.
If no confirmation of placement, remove and ventilate with BVM before reattempting.
4.1.6 Complications
Immediate
Hypoxia due to prolonged attempts.
Esophageal intubation.
Trauma to teeth, airway structures.
Vomiting and aspiration.
Delayed
Tube displacement.
Infection.
Tracheal stenosis from prolonged cuff pressure.
4.2.1 Indications
Need for immediate airway control in patients with intact gag reflex.
Combative or uncooperative patients requiring airway intervention.
4.2.2 Medications
Sedatives (Induction Agents)
Etomidate: Rapid onset, minimal hemodynamic effects.
Midazolam: Sedative, can cause hypotension.
Ketamine: Provides sedation and analgesia, maintains airway reflexes.
Paralytics
Depolarizing Agent:
Succinylcholine: Rapid onset, short duration.
Contraindications: Hyperkalemia, neuromuscular disorders, crush injuries, burns >24 hours old.
Non-Depolarizing Agents:
Rocuronium, Vecuronium: Longer duration.
4.2.3 Procedure Steps
Preparation
Ensure all equipment and medications are ready.
Assign roles to team members.
Preoxygenation
100% oxygen to fill functional residual capacity.
Pretreatment (If applicable)
Consider medications to mitigate response (e.g., lidocaine, atropine).
Induction
Administer sedative agent.
Paralysis
Administer paralytic once sedation confirmed.
Intubation
Proceed with intubation as per standard technique.
Post-Intubation Management
Secure tube, confirm placement.
Initiate mechanical ventilation.
Provide ongoing sedation and analgesia.
4.3.1 Supraglottic Airway Devices
King LT Airway
Single-lumen device with cuff seals.
Sizes based on patient height.
Insertion: Blindly inserted into esophagus, cuff inflated.
Laryngeal Mask Airway (LMA)
Sits over laryngeal inlet.
Various sizes; cuff inflated to seal.
Limited protection against aspiration.
I-Gel Airway
Non-inflatable, gel-like cuff.
Easier insertion, minimal trauma.
4.3.2 Indications and Contraindications
Indications
Difficult or failed intubation.
Airway management during cardiac arrest.
Short-term airway management when intubation not feasible.
Contraindications
Intact gag reflex.
High risk of aspiration.
Severe airway obstruction below glottis.
4.3.3 Insertion Techniques
Lubricate device.
Position head appropriately.
Insert device along the hard palate until resistance is felt.
Inflate cuff if applicable.
Confirm placement with chest rise, breath sounds, and capnography.
4.4.1 Needle Cricothyrotomy
Indications
Cannot intubate, cannot ventilate scenario.
Upper airway obstruction.
Equipment
Large-bore (12-14G) IV catheter.
High-pressure jet ventilation system or modified BVM.
Procedure
Palpate cricothyroid membrane between thyroid and cricoid cartilages.
Clean site aseptically.
Insert needle at 45-degree angle caudally while aspirating.
Confirm air aspiration, advance catheter over needle.
Secure catheter, connect to ventilation device.
Complications
Hypercarbia due to inadequate ventilation.
Barotrauma.
Subcutaneous emphysema.
4.4.2 Surgical Cricothyrotomy
Indications
Severe maxillofacial trauma.
Airway obstruction not relieved by less invasive means.
Procedure Overview
Incision through skin and cricothyroid membrane.
Insertion of tracheostomy tube or ETT.
Ventilation and verification as with intubation.
Complications
Bleeding.
Injury to surrounding structures.
Infection.
5.1.1 Indications
Patients who are intubated requiring controlled ventilation.
Respiratory failure unresponsive to non-invasive methods.
5.1.2 Transport Ventilators
Types
Pneumatically powered.
Electronically controlled.
Settings
Tidal Volume (Vt) : Typically 6-8 mL/kg of ideal body weight.
Respiratory Rate (RR) : Adjusted based on patient's needs.
FiO₂ (Fraction of Inspired Oxygen) : 21-100%, usually start at 100% then titrate.
PEEP (Positive End-Expiratory Pressure) : Generally 5 cm H₂O to prevent alveolar collapse.
5.1.3 Ventilation Modes
Assist-Control (A/C) : Delivers set volume/pressure with each breath; patient can trigger additional breaths.
Synchronized Intermittent Mandatory Ventilation (SIMV) : Delivers mandatory breaths synchronized with patient's efforts.
Pressure Support Ventilation (PSV) : Augments spontaneous breaths with set pressure.
5.1.4 Monitoring and Adjustments
Peak Inspiratory Pressure (PIP)
High PIP may indicate obstruction, bronchospasm, or kinks.
Alarms
High pressure, low pressure, apnea alarms must be monitored.
Waveforms
Flow, volume, pressure waveforms aid in troubleshooting.
5.1.5 Complications
Barotrauma: Over-distension leading to pneumothorax.
Hypoventilation/Hypoventilation: Adjust settings as needed.
Ventilator-Associated Pneumonia (VAP) : Minimize duration on ventilator.
5.2.1 Continuous Positive Airway Pressure (CPAP)
Indications
Acute pulmonary edema.
COPD exacerbations.
Sleep apnea.
Contraindications
Respiratory arrest.
Unconsciousness.
Facial trauma.
Vomiting.
Procedure
Apply mask snugly.
Start with low pressures (5 cm H₂O), titrate up.
Monitor for improvement.
5.2.2 Bilevel Positive Airway Pressure (BiPAP)
Indications
Similar to CPAP but allows separate inspiratory (IPAP) and expiratory (EPAP) pressures.
Advantages
Provides ventilatory support and reduces work of breathing.
Obstructive Lung Disease (Asthma, COPD)
Avoid high tidal volumes.
Prolonged expiratory phase to prevent air trapping.
Low respiratory rates.
Restrictive Lung Disease
Higher respiratory rates with lower tidal volumes.
Acidosis
Increase minute ventilation to "blow off" CO₂.
Capnometry vs. Capnography
Capnometry: Numeric reading of CO₂.
Capnography: Numeric and graphical representation (waveform).
Phase I (Baseline)
Inspiratory baseline; should be near zero.
Phase II (Expiratory Upstroke)
CO₂ from alveoli mixes with dead space air.
Phase III (Expiratory Plateau)
Reflects alveolar CO₂ level.
Phase 0 (Inspiratory Downstroke)
Inhalation begins; CO₂ level drops to baseline.
Verification of Intubation
Continuous waveform confirms correct tube placement.
Monitoring Ventilation
Changes in EtCO₂ reflect ventilation status.
Hyperventilation: Decreased EtCO₂.
Hypoventilation: Increased EtCO₂.
Circulatory Status
Sudden loss of EtCO₂ may indicate circulatory collapse.
During CPR
EtCO₂ levels correlate with cardiac output.
Levels above 10 mmHg suggest adequate compressions.
Sudden increase may indicate ROSC.
Metabolic Monitoring
Elevated EtCO₂ in cases of hypermetabolic states (fever, seizures).
Decreased EtCO₂ in metabolic acidosis (e.g., DKA).
Bronchospasm
Shark-fin appearance due to prolonged expiration.
Rebreathing CO₂
Elevated baseline; waveform does not return to zero
Leak in Ventilator Circuit
Irregular waveforms
Indications for Intubation vs. Alternative Airways
Consider patient condition, difficulty of intubation, and resources.
Risk Assessment
Weigh risks of procedures against benefits.
Difficult Airway Algorithm
Structured approach to managing anticipated and unanticipated difficult airways.
Includes backup plans (LMA, surgical airway).
Failed Airway Algorithm
Steps to take after unsuccessful intubation attempts:
Reattempt with adjustments.
Use alternative devices.
Consider waking the patient if safe.
Prepare for surgical airway.
Limited Space
Adapt techniques in confined areas.
Lighting Conditions
Ensure adequate illumination or use devices with built-in lights.
Noise and Distractions
Maintain focus and clear communication with team.
Scenario
22-year-old female with severe asthma attack, unresponsive to nebulized treatments, increasing fatigue.
Assessment
Rapid shallow breathing, diminished breath sounds, accessory muscle use.
EtCO₂ rising, indicating hypoventilation.
Actions
Decide on advanced airway management due to impending respiratory failure.
Prepare for intubation, consider the potential for difficult airway due to bronchospasm.
Use medications that minimize bronchial irritation.
Post-intubation, adjust ventilator settings to allow for longer expiratory phase.
Scenario
35-year-old male with facial trauma after motor vehicle collision, bleeding profusely, gurgling sounds.
Assessment
Airway compromised due to blood and swelling.
Limited visualization of landmarks.
Actions
Suction airway promptly.
Attempt to maintain airway with basic maneuvers.
Predict difficult airway; prepare alternative devices.
If unable to intubate, consider supraglottic airway.
Prepare for possible surgical airway if obstruction persists.
Mastering airway management and ventilation is essential for paramedics, as airway compromise can have immediate life-threatening consequences. This module has provided an in-depth exploration of advanced airway techniques, ventilation strategies, and the critical thinking required to make informed decisions in complex situations. Continuous practice and staying updated with current guidelines will enhance your proficiency and confidence in managing airways effectively.