Publications 

https://scholar.google.com/citations?user=5xKKY4UAAAAJ&hl=en 

As a main or corresponding author

Fluid biomarkers

11. HJ Kim, JE Park, W Shin, D Seo, S Kim, H Kim, J Noh, Y Lee, H Kim, YM Lim, H Kim, EJ Lee (2023). Distinct features of B cell receptors in neuromyelitis optica spectrum disorder among CNS inflammatory demyelinating diseases. J Neuroinflammation, 20(1), 225

10. HJ Kim, EJ Lee, SY Kim, H Kim, KW Kim, S Kim, H Kim, D Seo, BJ Lee, HT Lim, KK Kim, YM Lim (2023). Serum proteins for monitoring and predicting visual function in patients with recent optic neuritis. Sci Rep, 13 (1) 5609.

9. KW Kim, EJ Lee, SY Kim, HJ Jung, HJ Kim, S Kim, H Kim, D Seo, J So, J Kim, H Kim, KK Kim & YM Lim (2023). Disease characteristics of idiopathic transverse myelitis with serum neuronal and astroglial damage biomarkers. Sci Rep, 13 (1) 3988

8. YO Jang, HS Ahn, TN Dao, JY Hong, W Shin, YM Lim, SJ Chung, JH Lee, H Liu, B Koo, MG Kim, K Kim, EJ Lee, Y Shin (2023). Magnetic transferrin nanoparticles (MTNs) assay as a novel isolation approach for exosomal biomarkers in neurological diseases. Biomater Res, 16;27(1):12

7. H Kim, EJ Lee, YM Lim, KK Kim (2022). Glial fibrillary acidic protein in blood as a disease biomarker of neuromyelitis optica spectrum disorders. Front Neurol, 483

6. H Kim, EJ Lee, S Kim, LK Choi, HJ Kim, HW Kim, K Chung, D Seo, S Moon, KK Kim, YM Lim (2021). Longitudinal follow-up of serum biomarkers in patients with neuromyelitis optica spectrum disorder. Mult Scler J, 28 (4) 512-521  

5. EJ Lee, YM Lim, S Kim, LK Choi, H Kim, K Kim, HW Kim, JS Lee, Kk Kim (2020). Clinical implication of serum biomarkers and patient age in inflammatory demyelinating diseases. Ann Clin Transl Neurol 7(6):992-1001

4. H Kim,* EJ Lee,* S Kim, LK Choi, K Kim, H Kim, KK Kim, YM Lim (2020). Serum biomarkers in myelin oligodendrocyte glycoprotein antibody-associated disease. Neurol Neuroimmunol Neuroinflamm 17;7(3):e708  

3. EJ Lee, SU Kwon, JH Park, YJ Kim, KS Hong, S Yu, YH Hwang, JS Lee, J Lee, JH Rha, SH Heo, SH Ahn, WK Seo, JM Park, JH Lee, JH Kwon, SI Sohn, JM Jung, HY Kim, EG Kim, SH Kim, JK Cha, MS Park, HS Nam, DW Kang (2020). Changes in high-density lipoprotein cholesterol and cardiovascular risks: post-hoc analysis from the PICASSO trial. J Stroke, 1, 108.

2. EJ Lee, YM Lim, SY Kim, JK Lee, H Kim, JY Jin, YJi Oh, KK Kim, MD (2019). The clinical and prognostic value of antinuclear antibodies in NMO-IgG seropositive neuromyelitis optica spectrum disorder. J Neuroimmunol. 328: 1-4

1. EJ Lee,* Oh MS,* Kim JS, Chang DI, Park JH, Cha JK, Heo JH, Sohn SI, Kim DE, Kim HY, Kim J, Seo WK, Lee J, Park SW, Kim YJ, Lee BC (2018). Serotonin transporter gene polymorphisms may be associated with post-stroke neurologic recovery after escitalopram use. J Neurol Neurosurg Psychiatry 89(3):271-276 

Digital biomarker/therapeutics

9. EJ Lee, D Kim, YH Kim, E Namgung, JH Lee, Y Sasaki, T Watanabe, DW Kang (2023). Digital therapeutics with visual discrimination training for cortical blindness in patients with chronic stroke. J Stroke 25 (3), 409

8. S Jeong*, EJ Lee*, YH Kim, JC Woo, OW Ryu, M Kwon, SU Kwon, JS Kim, DW Kang (2022). Deep Learning Approach Using Diffusion-Weighted Imaging to Estimate the Severity of Aphasia in Stroke Patients. J Stroke 24 (1), 108-117       

7. H Lee,* EJ Lee,* S Ham, HB Lee, JS Lee, SU Kwon, Jong S Kim, N Kim, DW Kang (2020). Machine learning approach to identify stroke within 4.5 hours. Stroke, 51(3):860-866  

6. HJ Kim,* EJ Lee,* SH Jung, JW Lee, JS Kim, JB Kim, SU Kwon (2020). Cerebral Atherosclerosis and Early Ischemic Stroke After Left-Sided Valve Replacement Surgery. J Thorac Cardiovasc Surg 163(3):967-976.e6  

5. Lee EJ, Kim YH, Kim N, Kang DW (2017). Deep into the Brain: Artificial Intelligence in Stroke Imaging. J Stroke 19(3):277-285

4. Lee EJ, Cho YP, Lee SH, Lee JS, Nam HJ, Kim BJ, Kwon TW, Kang DW, Kim JS, Kwon SU (2016). Hemodynamic Tandem Intracranial Lesions on Magnetic Resonance Angiography in Patients Undergoing Carotid Endarterectomy J Am Heart Assoc. 5: e004153

3. Lee EJ, CH Chung, KH Choi, JW Lee, SJ Choo, SH Jung, DW Kang, JS Kim, SU Kwon (2018) The impact of cerebral atherosclerosis according to location on prognosis after coronary artery bypass grafting. Cerebrovasc Dis 46(5-6): 200-209

2. Lee EJ, Kang DW, Warach S. (2016). Silent New Brain Lesions: Innocent Bystander or Guilty Party? J Stroke 18(1):38-49

1. Lee EJ, Choi KH, Ryu JS, Jeon SB, Lee SW, Park SW, Park SJ, Lee JW, Choo SJ, Chung CH, Jung SH, Kang DW, Kim JS, Kwon SU. (2011) Stroke risk after coronary artery bypass graft surgery and extent of cerebral artery atherosclerosis. J Am Coll Cardiol. 57(18):1811-8

Clinical trials and other studies

12. SH Ha, DK Lee, G Park, BJ Kim, JY Chang, DW Kang, S Kwon, JS Kim, HJ Park, EJ Lee (2023). Prospective Analysis of Video Head Impulse Tests in Patients With Acute Posterior Circulation Stroke. Front Neurol, 14, 1256826

11. J Hwang, H Yi, M Jang, JG Kim, SU Kwon, N Kim, EJ Lee (2022). Air Pollution and Subarachnoid Hemorrhage Mortality: A Stronger Association in Women than in Men. J Stroke 24(3): 429-432

10. S Kim, EJ Lee, K Kim, D Seo, S Moon, KK Kim, YM Lim (2022). Quality of life of patients with multiple sclerosis and neuromyelitis optica spectrum disorders: cross-sectional and longitudinal analysis. Mult Scler Relat Disord, 58, 103500.  

9. EJ Lee, JS Kim, Dl Chang, JH Park, SH Ahn, JK Cha, JH Heo, Sl Sohn, BC Lee, DE Kim, HY Kim, S Kim, DY Kwon, J Kim, WK Seo, J Lee, SW Park, SH Koh, JY Kim, S Choi-Kwon, MS Kim, JS Lee (2020). Post-stroke depressive symptoms: Varying responses to escitalopram by individual symptoms and lesion location. J Geriatr Psychiatry Neurol 34(6):565-573

8. EJ Lee, JS Kim, DI Chang, JH Park, SH Ahn, JK Cha, JH Heo, Sl Sohn, BC Lee, DE Kim, HY Kim, S Kim, DY Kwon, J Kim, WK Seo, J Lee, SW Park, SH Koh, JY Kim, S Choi-Kwon (2020). Depressive symptoms in stroke patients: are there sex differences? Cerebrovasc Dis, 1-7

7. YJ Park, H Kwon, KB Lee, H Lee, JS Baek, Y Song, SB Jeon, YJ Kim, EJ Lee (2019). A Successful Mechanical Thrombectomy for Acute Basilar Artery Occlusion in a Patient Who Had Undergone Fontan Operation. J Neurosonol Neuroimag 11(2):1-4

6. H Kwon, KB Lee, YJ Park, G Kim, DH Lee, YM Lim, KK Kim, EJ Lee (2019). A Successful Stent-Assisted Coil Embolization in a Patient with Oculomotor Palsy Due to Partially Thrombosed-Aneurysm in Cavernous Internal Carotid Artery (2019). J Korean Neurol Assoc. 37 (4), 426-428

5. Lee EJ, JS Kim, DI Chang, JH Park, SH Ahn, JK Cha, JH Heo, SI Sohn, BC Lee, DE Kim, HY Kim, S Kim, DY Kwon, J Kim, WK Seo, J Lee, SW Park, SH Koh, Jin Young Kim, Smi Choi-Kwon, Min-Sun Kim, Ji Sung Lee (2018). Differences in Therapeutic Responses and Factors Affecting Post-Stroke Depression at a Later Stage According to Baseline Depression. J Stroke 20(2): 258–267.

4. Kim BJ*, Lee EJ*, Kwon SU, Park JH, Kim YJ, Hong KS, Wong KS, Yu S, Hwang YH, Lee JS, Lee J, Rha JH, Heo SH, Ahn SH, Seo WK, Park JM, Lee JH, Kwon JH, Sohn SI, Jung JM, Navarro J, Kang DW (2018). Prevention of cardiovascular events in Asian patients with ischaemic stroke at high risk of cerebral haemorrhage (PICASSO): a multicentre, randomised controlled trial. Lancet Neurol 2018:17: 509-18  

3. Lee EJ, Noh SM, Kang DW, Kim JS, Kwon SU. (2016). Impact of provoking risk factors on the prognosis of cerebral venous thrombosis in Korean patients. J Stroke 18(2): 187-194  

2. Lee EJ, Nah HW, Kwon JY, Kang DW, Kwon SU, Kim JS. (2014) Ischemic stroke in patients with cancer: is it different from usual strokes? Int J Stroke. 9(4):406-412

1. Lee EJ, Kim MJ, You CG, Jeon SB, Lee DH, Kang DW, Kwon SU. (2010). Development of subdural hemorrhage in a patient with cerebral venous sinus thrombosis. J Korean Neurol Assoc. 28(3):214-217

Basic studies

2. Lee EJ, Lee Hyejin, Huang Tzyy-Nan, Chung Changuk, Shin Wangyong, Kim Kyungdeok, Koh Jae-Young, Hsueh Yi-Ping, and Kim Eunjoon. (2015) Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation. Nat Commun. 6:7168  

1. Lee EJ, Choi SY, and Kim E. (2015) NMDA receptor dysfunction in autism spectrum disorders. Curr Opin Pharmacol. 20:8-13

 As a co-author

40. E Namgung, EJ Lee, YH Kim, DW Kang (2024). White Matter Structural Connectivity Associated With Visual Field Recovery After Stroke. J Stroke. 26 (1), 116-120

39. SH Ha, J Hwang, N Kim, EJ Lee, BJ Kim, SU Kwon (2023). Spatiotemporal association between air pollution and stroke mortality in South Korea. J Stroke Cerebrovasc Dis, 32 (11), 107348

38. DY Kim, JY Shin, JE Lee, HN Kim, SJ Chung, HS Yoo, SJ Kim, HJ Cho, EJ Lee, SJ Nam, SH Kim, J Jang, SE Lee, PH Lee (2023).  A selective ER-phagy exerts neuroprotective effects via modulation of α-synuclein clearance in parkinsonian models. PNAS, 120 (37) e2221929120

37. JK Oh, J Jung, SA Lee, S Lee, EJ Lee, E Chang, CK Kang, PG Choe, YJ Kim, NJ Kim, JM Song, DH Kang, JK Song, M Oh, WB Park, DH Kim (2023). Impact of routine brain imaging on the prognosis of patients with left-sided valve infective endocarditis without neurological manifestations. Int J Cardiol, 131175

36. JH Oh, S Jo, KW Park, EJ Lee, SH Lee, YS Hwang, HR Jeon, Y Ryu, HJ Yoon, SM Chun, CJ Kim, TW Kim, CO Sung, S Chae, SJ Chung (2023). Whole-genome sequencing reveals an association between small genomic deletions and an increased risk of developing Parkinson’s disease. Exp Mol Med, 1-10 

35. H Jeon, M Kim, W Park, JS Lim, E Lee, H Cha, JS Ahn, JH Kim, SH Hong, JE Park, EJ Lee, CW Woo, S Lee (2021). Upregulation of AQP4 Improves Blood–Brain Barrier Integrity and Perihematomal Edema Following Intracerebral Hemorrhage.  Neurotherapeutics, 1-15 

34. E Lie, Y Yeo, EJ Lee, W Shin, K Kim, KA Han, E Yang, TY Choi, M Bae, S Lee, SM Um, SY Choi, H Kim, J Ko, E Kim (2021). Communications Biology 4(1):1138. 

33. T Fujii, EJ Lee, Y Miyachi, R Yamasaki, YM Lim, K Iinuma, A Sakoda, KK Kim, J Kira (2021). Antiplexin D1 antibodies relate to small fiber neuropathy and induce neuropathic pain in animals. Neurol Neuroimmunol Neuroinflamm 8 (5). 

32. BJ Kim, SK Jang, YH Kim, EJ Lee, JY Chang, SU Kwon, JS Kim, DW Kang (2021). Diagnosis of acute central dizziness with simple clinical information using machine learning. Front Neurol 12:691057. 

31. B Kwon, EJ Lee, S Park, JS Lee, MH Lee, D Jeong, D Lee, HS Kwon, Dl Chang, JH Park, JK Cha, JH Heo, SI Sohn, DE Kim, S Choi-Kwon, JS Kim (2021). Long-term changes in post-stroke depression, emotional incontinence, and anger. J Stroke 23(2):263-272. 

30. HW Kim, H Kim, D Jeong, K Chung, EJ Lee, YM Lim, KK Kim (2021). Adrenomyeloneuropathy with cerebral involvement due to a novel frameshift variant in ABCD1 gene. Ann Clin Neurophysiol 23(1):61-64. 

29. HS Kwon, EJ Lee, D Lee, JS Lee, JS Kim (2021). Nitrogen Dioxide Exposure May Be Associated with Poststroke Emotional Symptoms. J Clin Neurol, 17(2):317.

28. KW Park, EJ Lee, JS Lee, J Jeong, N Choi, S Jo, M Jung, JY Do, DW Kang, JG Lee, SJ Chung (2021). Machine learning–based automatic rating for cardinal symptoms of Parkinson disease. Neurology, 96(13):e1761-e1769. 

27. MR Yoo, YM Chun, KH Choi, SU Kwon, EJ Lee (2020). Effectiveness of Formal Dysphagia Screening for Stroke Patients. Journal of the Korean Dysphagia Society, 11(1):43-51. 

26. KW Park, JH Ko, N Choi, S Jo, YJ Park, EJ Lee, SJ Kim, SJ Chung, CS Lee (2020). Cortical hypometabolism associated with cognitive impairment of multiple system atrophy. Parkinsonism Relat Disord 81, 151-156

25. H Kim, Y Lee, YH Kim, YM Lim, JS Lee, J Woo, SK Jang, YJ Oh, HW Kim, EJ Lee, DW Kang, KK Kim (2020). Deep Learning-Based Method to Differentiate Neuromyelitis Optica Spectrum Disorder From Multiple Sclerosis. Front Neurol 11, 1642.

24. H Kim, YM Lim, EJ Lee, HW Kim, HS Ahn, KK Kim (2020). Anti-CASPR2-Antibody-Positive Isaacs' Syndrome Presenting with Myokymia, Neuropathic Pain, and Hyperhidrosis. J Clin Neurol 16(4), 699-701.

23. SK Jang, JY Chang, JS Lee, EJ Lee, YH Kim, JH Han, DI Chang, HJ Cho, JK Cha, KH Yu, JM Jung, SH Ahn, DE Kim, SI Sohn, JH Lee, KP Park, SU Kwon, JS Kim, DW Kang, KOSNI Investigators (2020). Reliability and Clinical Utility of Machine Learning to Predict Stroke Prognosis: Comparison with Logistic Regression. J Stroke 22(3); 403-406.

22. H Kim, YM Lim, EJ Lee, YJ Oh, KK Kim (2020). Clinical and imaging features of patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy and cysteine-sparing NOTCH3 mutations. PloS one 15(6):e0234797

21. H Kim, YM Lim, G Kim, EJ Lee, JH Lee, HW Kim, KK Kim (2020). Choroid plexus changes on magnetic resonance imaging in multiple sclerosis and neuromyelitis optica spectrum disorder. J Neurol Sci 116904

20. YM Lim, H Kim, EJ Lee, HW Kim, HJ Kim, KK Kim (2020). Beneficial effects of intravenous immunoglobulin as an add-on therapy to azathioprine for NMO-IgG-seropositive neuromyelitis optica spectrum disorders Mult Scler Relat Disord, 102109

19. W Shin, K Kim, B Serraz, YS Cho, D Kim, M Kang, EJ Lee, H Lee, YC Bae, P Paoletti, E Kim (2020). Early correction of synaptic long-term depression improves abnormal anxiety-like behavior in adult GluN2B-C456Y-mutant mice Plos Biol in press

18. JS Kim, KB Lee, JH Park, SM Sung, K Oh, EG Kim, D Chang, YH Hwang, EJ Lee, WK Kim, C Ju, BS Kim, JM Ryu (2020). Safety and Efficacy of Otaplimastat in Patients with Acute Ischemic Stroke Requiring tPA (SAFE‐TPA): A Multicenter, Randomized, Double‐blind, Placebo‐Controlled Phase 2 Study. Ann Neurol, 87(2), 233-245

17. Y Moon, KS Eah, EJ Lee, DW Kang, SU Kwon, JS Kim, HT Lim (2019). Neuro-Ophthalmologic Features and Outcomes of Thalamic Infarction: A Single-Institutional 10-Year Experience. J Neuroophthalmol, 41(1):29-36. 

16. HS Kwon, D Lee, MH Lee, S Yu, JS Lim, KH Yu, MS Oh, JS Lee, KS Hong, EJ Lee, DW Kang, SU Kwon (2019). Post-stroke cognitive impairment as an independent predictor of ischemic stroke recurrence: PICASSO sub-study. J Neurol. 1-6

15. KW Park, N Choi, HS Ryu, MS Kim, EJ Lee, SJ Chung (2019). Pupillary dysfunction of multiple system atrophy: Dynamic pupillometric findings and clinical correlations. Parkinsonism Relat Disord, 65, 234-237.

14. D Lee, DH Lee, DC Suh, HS Kwon, DE Jeong, JG Kim, JS Lee, JS Kim, DW Kang, SB Jeon, EJ Lee, KC Noh, SU Kwon (2019). Intra-arterial thrombectomy for acute ischaemic stroke patients with active cancer. J Neurol, 1-8

13. Lee H*, Shin W*, Kim K*, Lee S, Lee EJ, Kim J, Kweon H, Lee E, Park H, Kang M, Yang E, Kim H, and Kim E. (2019). NGL-3 in the regulation of brain development, Akt/GSK3b signaling, long-term depression, and locomotive and cognitive behaviors. PLoS Biol, 17(6), e2005326..

12. Kim H, Lee EJ, Kim SK, Kim KK, Lim YM (2019). Efficacy and safety of alemtuzumab in Korean multiple sclerosis patients Mult Scler Relat Disord, 30, 247-251.

11. Kim H, Lim YM, Oh YJ, Lee EJ, Kim KK (2018). Comparison of Brain Magnetic Resonance Imaging between Myotonic Dystrophy Type 1 and Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. PLOS ONE 13(12):e0208620

10. Kim H, Lim YM, Lee EJ, Oh YJ, Kim KK (2018). Factors predicting remission in thymectomized patients with acetylcholine receptor antibody-positive myasthenia gravis. Muscle Nerve 58(6):796-800.  

9. S Ha, TH Yoon, YY Shin, EJ Lee, BJ Kim (2018). Miller-Fisher Syndrome Presenting with Bilateral Pseudo-Internuclear Ophthalmoplegia. J Korean Neurol Assoc. 36(2):100-102

8. JG Kim, EJ Lee, SU Kwon (2017). Asymptomatic Free-Floating Thrombus in the Chronic Occluded Common Carotid Artery. J Neurosonol Neuroimag 9(1): 18-20.

7. Kim H, Lim YM, Lee EJ, Oh YJ, Kim KK (2017). Correlation between the CAG repeat size and electrophysiological findings in patients with spinal and bulbar muscular atrophy. Muscle Nerve 57(4):683-686 

6. SB Jeon, SM Ryoo, DH Lee, SU Kwon, S Jang, EJ Lee, SH Lee, JH Han, MJ Yoon, S Jeong, YU Cho, S Jo, SB Lim, JG Kim, HB Lee, SC Jung, KW Park, MH Lee, DW Kang, DC Suh, JS Kim (2017). Multidisciplinary Approach to Decrease In-Hospital Delay for Stroke Thrombolysis. J Stroke 19(2): 196–204  

5. Kim JS, Lee EJ, Chang DI, Park JH, Ahn SH, Cha JK, Heo JH, Sohn SI, Lee BC, Kim DE, Kim HY, Kim S, Kwon DY, Kim J, Seo WK, Lee J, Park SW, Koh SH, Kim JY, Choi-Kwon S (2017). Efficacy of early administration of escitalopram on post-stroke depressive/emotional symptoms and neurologic dysfunction: a multicenter, double blind, randomized, placebo-controlled study. Lancet Psychiatry 4(1):33-41

4. Kelly PJ, Albers GW, Chatzikonstantinou A, Marchis Gian, Ferrari J, George P, Katan M, Knoflach M, Kim JS, Li L, Lee EJ, Olivot JM, Purroy F, Raposo N, Rothwell P, Sharma V, Song B, Tsivgoulis G, Walsh C, Xu Yuming, Merwick A (2016). Validation and comparison of imaging-based scores for prediction of early stroke risk after transient ischaemic attack: a pooled analysis of individual-patient data from cohort studies. Lancet Neurol 15:1238-47

3. Li Y*, Zhang P*, Choi TY, Park SK, Park H, Lee EJ, Lee D, Roh JD, Mah W, Kim R, Kim Y, Kwon H, Bae YC, Choi SY, Craig AM, and Kim E. (2015). Splicing-dependent Trans-synaptic SALM3-LAR-RPTP Interactions Regulate Excitatory Synapse Development and Locomotion. Cell Rep 12:1618-1630

2. Lee H, Lee EJ, Song YS, and Kim E. (2013). LTD-inducing stimuli promote cleavage of the synaptic adhesion molecule NGL-3 through NMDA receptors, matrix metalloproteinases, and presenilin/g-secretase. Phil Trans R Soc B. 369:20130158  

1. Kwon JY, Lee EJ, Kim JS. (2010). Brainstem infarction secondary to persistent trigeminal artery occlusion: successful treatment with intravenous rt-PA. Eur Neurol. 64(5):311

Book

Eun-Jae Lee, Hyo-Jung Kim, Ji-Soo Kim (2020). Chapter: Ocular, Vestibular, and Otologic Syndromes, Posterior Circulation Stroke, Springer, Singapore, 101-119,