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RECENT HIGHLIGHTS

Popat AK, Simon RC, Aoyama BB, Wokhlu A, Ehrlich AT, Harwell CC, Margolis EB. Mu opioid receptor mRNA and protein localization across the rat and mouse habenula. bioRxiv. 2025 Dec 19;. doi: 10.64898/2025.12.16.694766. PubMed PMID: 41446124; PubMed Central PMCID: PMC12724406. 

Li Guan YH, Kieffer BL, von Zastrow M, Ehrlich AT. GPR88 localization to primary cilia in neurons is cell-type specific. Life Sci Alliance. 2026 Feb;9(2). doi: 10.26508/lsa.202503366. Print 2026 Feb. PubMed PMID: 41330618; PubMed Central PMCID: PMC12672383. 

Mathis VP, Ehrlich AT, Darcq E. The neural circuits and signalling pathways of opioid use disorder. Nat Rev Neurosci. 2025 Dec;26(12):778-797. doi: 10.1038/s41583-025-00982-7. Epub 2025 Oct 27. Review. PubMed PMID: 41145836. 

Kostyanovskaya E, Lasser MC, Wang B, Schmidt J, Bader E, Buteo C, Arbelaez J, Sindledecker AR, McCluskey KE, Castillo O, Wang S, Dea J, Helde KA, Graglia JM, Brimble E, Kastner DB, Ehrlich AT, State MW, Willsey AJ, Willsey HR. Convergence of autism proteins at the cilium. bioRxiv. 2025 Jan 14;. doi: 10.1101/2024.12.05.626924. PubMed PMID: 39677731; PubMed Central PMCID: PMC11643032. 

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Fagan RR, Lee DF, Geron M, Scherrer G, von Zastrow M, Ehrlich AT. Selective targeting of mu opioid receptors to primary cilia. Cell Rep. 2024 May 28;43(5):114164. doi: 10.1016/j.celrep.2024.114164. Epub 2024 Apr 27. PubMed PMID: 38678559; PubMed Central PMCID: PMC11257377. 

Ehrlich AT, Couvineau P, Schamiloglu S, Wojcik S, Da Fonte D, Mezni A, von Zastrow M, Bender KJ, Bouvier M, Kieffer BL. Visualization of real-time receptor endocytosis in dopamine neurons enabled by NTSR1-Venus knock-in mice. Front Cell Neurosci. 2022;16:1076599. doi: 10.3389/fncel.2022.1076599. eCollection 2022. PubMed PMID: 36523815; PubMed Central PMCID: PMC9745132. 

Ehrlich AT, Semache M, Couvineau P, Wojcik S, Kobayashi H, Thelen M, Gross F, Hogue M, Le Gouill C, Darcq E, Bouvier M, Kieffer BL. Ackr3-Venus knock-in mouse lights up brain vasculature. Mol Brain. 2021 Sep 28;14(1):151. doi: 10.1186/s13041-021-00862-y. PubMed PMID: 34583741; PubMed Central PMCID: PMC8477500. 

Ehrlich AT, Semache M, Gross F, Da Fonte DF, Runtz L, Colley C, Mezni A, Le Gouill C, Lukasheva V, Hogue M, Darcq E, Bouvier M, Kieffer BL. Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons. iScience. 2019 Apr 26;14:47-57. doi: 10.1016/j.isci.2019.03.011. Epub 2019 Mar 15. PubMed PMID: 30925410; PubMed Central PMCID: PMC6439305.