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Image courtesy of A. Stanisławska, 2016
SB-iGEM 2019: Bacto-Basics
SB-iGEM 2019: Bacto-Basics
The bacterium Komagataeibacter rhaeticus has the ability to naturally produce bacterial cellulose (BC) which possesses many unique, highly useful properties suitable for a wide range of applications. We hypothesize that an optogenetic circuit in an engineered strain of K. rhaeticus grown in an optimized bioreactor can spatially control attachment of proteins to the surface of BC membranes to enable fine-tuning of these properties for different applications.
Image courtesy of Mother Nature Network
iTesla-SoundBio 2018: Factor C Synthesis
iTesla-SoundBio 2018: Factor C Synthesis
Project Abstract: Synthesizing Factor C, a protein responsible for starting the coagulation cascade in LAL testing, into B. subtilis as an alternative towards the biomedical standard of bleeding horseshoe crabs for their amoebocytes. Afterwards, designing a detection mechanism to detect and signal for the presence of endotoxin once Factor C is cleaved.
2018 iT-SB Team
Katherine Holo, Sophie Liu, JJ Wheeler, Sarah Alvi, Charlie Anderson, Vrishab Sathish Kumar, David Lu, Juntao Zhong, Hanul Kim, Ishika Mukherjee, Keerthana Thammana, Rachel Gao, Deepali Juneja, and Alex Richardson
Image courtesy of PNAS2
iTesla-SoundBio 2017: PCB Dechlorination
iTesla-SoundBio 2017: PCB Dechlorination
Project Abstract: Transferring genes responsible for producing PCB-dechlorinating enzymes from the anaerobic D. mccartyi bacterium, in which they are naturally found, into E.coli, an easier-to-work-with bacterium.
2017 iT-SB Team
Roya Amini-Naieni, Mary Elizabeth Adler, Joshua Argote, Amol Garg, JJ Wheeler, Sarah Alvi, Larry Wang, Karen Zhang, Keerthana Thammana, Matthew Saveliev, and Christina Long
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