We have studied the interaction of an air bubble with a vortical structure, namely, a (water) vortex ring, while the bubble is inside the ring. The focus is on the effects of the bubble-to-vortex size ratio on both the bubble dynamics and vortex ring dynamics. On the bubble side, its deformation and breakup dynamics are characterized by different regimes of the size ratios and the Weber numbers. Simultaneously, several features related to the spatio-temporal dynamics of the vortex ring, such as the ring growth, deformations, propagation, and azimuthal vorticity, are reported.Â