Viruses & Cancer
Viruses & Cancer
Epstein Barr- Mosquitoes- NK/T Cell Lymphoma
Case Rep Dermatol. 2019 Jun 26;11(2):194-197. doi: 10.1159/000501358. eCollection 2019 May-Aug.
Mosquito Bite-Induced Localized NK/T-Cell Lymphoma Relapsed in a Patient with Complete Remission of Extranodal NK/T-Cell Lymphoma, Nasal Type.
Kondo M1, Mizutani M2, Yamanaka K1.
1 Department of Dermatology, Mie University Graduate School of Medicine, Tsu, Japan.
2 Department of Hematology and Oncology, Matsusaka Chuo General Hospital, Matsusaka, Japan.
We report a rare case of localized NK/T-cell lymphoma following a mosquito bite after achieving complete response of extranodal NK/T-cell lymphoma, nasal type (ENKL).
T cells and NK cells infected by Epstein-Barr virus (EBV) lead to NK/T-cell lymphoma, including ENKL.
Lymphoma related to mosquito bites usually requires a prolonged treatment course, and the disease onset of hypersensitivity begins in early childhood. In the current case, the patient had no history of hypersensitivity to mosquito bites.
We speculate that the latently EBV-infected NK/T cells in the blood were reactivated by mosquito gland antigens, expanded abnormally, and accumulated at the site of the mosquito bite.
KEYWORDS:
Complete response; Epstein-Barr virus infection; Extranodal NK/T-cell lymphoma, nasal type; Malignant lymphoma; Mosquito bite
PMID: 31320868
PMCID: PMC6616089
DOI: 10.1159/000501358
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Last Updated- July 2019
Lucy Barnes
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