Thank you to those who have kindly contributed
This information to help others!
None of the information below is to be considered medical advice. It is simply information that some people in this situation felt was helpful.
From a LLMD/Patient- June 2016
I am following the gcMAF cream which is being used for cancer and Lyme.
http://creamfeedback.weebly.com
The Mafactive is approved I believe in the US as an external cream. To make it more valid they do not make any claims for it.
One of the distributors in the US is Candice Lee-Bradstreet, who is the daughter in law of the late Dr Bradstreet.
USA - Practitioners using and selling MAFActive products
* Pure Living Health and Wellness, Florida http://www.purelivinghealthandwellness.com/mafactive.html tel: (941) 485-6361
* Krizten Breidenich, Gut Instinct Nutrition, Seattle, www.gutinstinctnutrition.com, tel 206 551 9282
USA distributors
* Candice Lee-Bradstreet, candicembradstreet@gmail.com tel 810-766-3032 www.reactivatedwellness.com
* MWS Distributing. Website, www.mwsdistributing.com, email. mwsdistributing@gmail.com
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Keebler, patient advocate, offered the following information.
Study says a major blood cancer is 11 distinct diseases
By Adam Brimelow - Health correspondent, BBC News - 8 June 2016
http://www.bbc.com/news/health-36479291
There are many more ways to address inflammation - and other aspects, too - that don't carry the side effects of doxycycline (such as candida issues). For starters:
PubMed Search of medical literature:
http://www.ncbi.nlm.nih.gov/pubmed/?term=Berberine
Berberine - 4035 abstracts
Berberine, inflammation - 189 abstracts
Berberine, MMP9 - 9 abstracts
Berberine, cancer - 587 abstracts
The same sort of cross searches yield good results with andrographis and also with allicin. Stinging Nettle Leaf is also a wonderful herb to help decrease inflammation and calm the cytokine cascade.
^^^^^^
Shared by Carl Tuttle, Patient Advocate- July 2016
Prostate cancer here; radioactive seed implant Sept 19, 2015. Current PSA 1.8
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Shared by Peter Kraus- July 2016
These have been posted previously, but may be useful anyway - articles relevant to cancer and Lyme:
cancer as a metabolic disease:
http://www.ncbi.nlm.nih.gov/pubmed/26217661
treating cancer with ketogenic diet and hyperbaric oxygen:
http://www.ncbi.nlm.nih.gov/pubmed/26061868
treating cancer with antibiotics:
http://www.ncbi.nlm.nih.gov/pubmed/25625193
deuterium-depleted water as cancer treatment:
https://www.ncbi.nlm.nih.gov/pubmed/23441611
https://www.ncbi.nlm.nih.gov/pubmed/18815148
A paper linking the biochemistry of dueterium-depletion to the ketogenic diet:
https://www.ncbi.nlm.nih.gov/pubmed/26826644
For the metabolic similarity between cancer and Lyme, see the following. Because of the metabolic-similarity between Lyme and cancer, it seems at least possible that Lyme could be treated with Deuterium-depleted water, in the same way that cancer is. According to Dr. Somlyai, treatment of cancer with Deuterium-depleted water produces a Herx.
Two metabolic vulnerabilities of B. Burgdorferi, the prevalent Alzheimer’s pathogen
The following is based on the work of Dr. Thomas Seyfried. He has found that cancer can be treated/inhibited with the ketogenic diet, exogenous ketone dietary administration, and hyperbaric oxygen, either separately, or in combination. This is based on a metabolic impairment that seems to occur for most or all cancer cells. Surprisingly, B. burgdorferi, the agent of Lyme disease, shares this metabolic lack of capability. This suggests that Lyme infection can be treated using Dr. Seyfried's methods for cancer treatment.
If Lyme can be treated using such methods, then it is quite possible that Alzheimer’s can also, since 90% of autopsied AD brains are found to be infected with pathogenic spirochetes. Relevant articles and other resources for the above claim can be found as a postscript at the end of this article.
Here are the details regarding the similarity between Lyme and cancer:
With regard to Lyme, it is known that the cellular respiration of the Lyme bacterium lacks the Krebs cycle and oxidative phosphorylation. This was concluded by the authors of the following article on the genomics of the bacterium (see section on energy metabolism):
http://www.nature.com/nature/journal/v390/n6660/full/390580a0.html
This lack of two important features of cellular respiration is similar to the impaired respiration of cancer cells. It means that the main fuel for Lyme bacteria is glucose, or carbs, according to the article mentioned above. It also means that they can not use ketones, which are processed through the Krebs cycle, because there is no Krebs cycle present.
With regard to cancer, in work done by Thomas Seyfried, it is shown that cancer cells have impaired energy metabolism. Normal cells generate 90% of their energy through aerobic means. Cancer cells produce only 40% of their energy needs aerobically. Thus, it is clear that there is an impairment of the oxidative phosphorylation pathway in cancer cells. It appears that this is a unifying concept for cancer, and it appears that most or all cancers share this impaired metabolism. Another feature of this impaired metabolism is that cancer cells can not process ketones, whereas normal cells can. This implies that the Krebs cycle is either impaired or non-functional in cancer cells.
http://www.ncbi.nlm.nih.gov/pubmed/26217661
Thus, the cellular respiration of both Lyme and cancer cells share the impairment (or non-existence in the case of Lyme) of both the Krebs cycle and of Oxidative phosphorylation.
There are two therapeutic strategies for treating cancer based on the above: 1. the calorie restricted ketogenic diet (KD-R, a low carb. and high fat diet), and 2. hyperbaric oxygen Treatment (HBOT). Both of these have been shown by Seyfried and/or D’Agostino in published papers to be effective means for inhibiting cancer cell growth. When used together, they have a synergistic effect.
1. The KD-R works against cancer cells because they require sugar as their main source of energy. They can not use ketones. The KD-R produces high levels of ketones and low blood sugar levels, and this puts a metabolic stress on cancer cells that can reduce their metabolic activity and cause their death.
2. HBOT causes cancer cells to explode, and does not affect normal cells in this way. This appears to be due to the impaired oxidative phosphorylation of cancer cells. It is apparent that normal cells can use "excess" oxygen in an ostensibly non-harmful way, but that cancer cells can not.
http://www.ncbi.nlm.nih.gov/pubmed/26061868
The two metabolic vulnerabilities of the Lyme bacterium are identical/similar to those of cancer cells, namely, both cancer cells and the Lyme bacterium 1. are dependent on sugar and carbs for energy metabolism, and 2. have reduced ability to handle oxygen.
At a deeper level, it may be that the ketogenic diet is acting against cancer through the mechanism of deuterium depletion:
http://www.ncbi.nlm.nih.gov/pubmed/26826644
Treatment Considerations:
Since the KD-R and HBOT have been shown to be effective for cancer control, and because of the metabolic similarities of cancer to Lyme metabolism, we can expect that these two treatments will also be effective for Lyme infection. Of course, we know already that HBOT has been discovered by Lyme-treating doctors to be effective, so this is not new. However, the KD-R does not seem to have been widely explored as a treatment for Lyme, and it appears that it may provide a new opportunity for treatment.
Questions about the safety of HBOT need to be answered. There do not seem to be any controlled studies to date. There may be similar questions about KD-R until controlled studies are done.
The concomitant use of anti-Lyme agents may improve the effects of KD-R. Dr. Eva Sapi has shown that Stevia is an effective agent for killing Lyme bacteria, and is a biofilm agent, and that it can kill the dormant forms of the bacteria. Dr. Sapi mentioned that when she did that experiment, she used low sugar levels. It could be that the bacteria evaluate Stevia as being sugar, are woken up, activate their metabolism, and then die because there really is no energy source available.
The article by Dr. Sapi on Stevia:
http://www.akademiai.com/doi/pdf/10.1556/1886.2015.00031
A similar article on other agents:
http://onlinelibrary.wiley.com/doi/10.1111/jam.12970/full
Evidence for the participation of pathogenic spirochetal bacteria in Alzheimer’s pathology
The following article by a periodontist at NYU, Dr. Angela Kamer, finds that Alzheimer's can be identified with 80% accuracy using blood testing for antibodies to oral bacteria:
http://www.ncbi.nlm.nih.gov/pubmed/19767111
Two authors are featured below. Both have provided evidence that AD is caused by bacterial infection of the brain. One is a neurologist, and the other is a pathologist. The work of each reinforces that of the other.
I. Dr. Miklossy
What follows is a brief description of, and reference to, a paper by the neurologist J. Miklossy. It is initially shocking to learn that 90% of autopsied AD brains are infected with pathogenic spirochetes (25% with Lyme and more than 65% percent with spirochetes which originate in the mouth and migrate to the brain). These are similar to the bacteria which cause syphilis. Here are the particulars:
1. Lyme disease and syphilis are both caused by spirochetal bacteria.
2. Syphilis is known to cause dementia. Also, Lyme disease (transmitted to humans by tick bite) is known to cause severe cognitive impairment.
3. A total of 90% of autopsied Alzheimer's patient brains are found to be infected with pathogenic spirochetal bacteria. The infected brains consist of two subgroups: 1. Lyme bacteria are found in 25% (this is 13 times higher than in the control population) of autopsied Alzheimer's brains, while 2. more than 65% of such brains are found to be infected by other pathogenic spirochetes (from the mouth). These percentages are statistically significantly higher than in the general population.
4. The bacterial infection described above is co-located with the Alzheimer's plaques.
5. The A-Beta protein which accumulates in Alzheimer's brains is an anti-microbial protein (i.e. it kills bacteria). This (along with #4 above) suggests that its proliferation may be a physiological response to infection.
6. When mammalian neural cells are cultured with added Lyme bacteria, the characteristic pathological hallmarks of Alzheimer's disease (i.e plaque build-up, fibrils, etc.) are found to occur.
(Source for the above: Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria. Miklossy J. Journal of Neuroinflammation. 2011; 8: 90. Published online 2011 August 4. doi: 10.1186/1742-2094-8-90 PMCID: PMC3171359)
If you do not have time to read the entire article, there are two dramatic bar charts from it comparing the prevalence of bacterial infection between the AD and non-AD subjects:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171359/figure/F1/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171359/figure/F2/
The entire article can be found at:
http://www.ncbi.nlm.nih.gov/pubmed/21816039
Alzheimer's disease - a neurospirochetosis. Analysis of ...
J Neuroinflammation. 2011 Aug 4;8:90. doi: 10.1186/1742-2094-8-90. Research Support, Non-U.S. G
II. Dr. MacDonald
Dr. MacDonald has created a three part series of YouTube videos explaining the connection between brain infection and AD. In addition, he has created a narrated slide tour of AD brain pathology. These four videos can be found at:
https://www.youtube.com/watch?v=r8tESJVvM88
The Biology of Lyme Disease: An Expert's Perspective (Pa...
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Dr. Alan MacDonald: Pathologist, Lyme Disease Expert -- Part II
Dr. Alan MacDonald: Pathologist, Lyme Disease Expert -- ...
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Dr. Alan MacDonald- Pathologist Lyme Disease Expert - Part III
Dr. Alan MacDonald- Pathologist Lyme Disease Expert - ...
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Biofilms Alive in Alzheimer's Disease Plaques
Biofilms Alive in Alzheimer's Disease Plaques
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You may also be interested in the materials that have been created by Dr. Elizabeth Maloney. She has created a set of 3 DVD's on the subject of Lyme. I believe that she is the only MD whose in-person (i.e. not using the DVD's) course on Lyme has been approved for CME credit.
Lessons in Lyme is an educational series on Lyme disease and other tick-borne illnesses. Each segment reviews a different topic in detail. Written by Dr. Elizabeth ...
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Thank you for your interest.
Peter Kraus
Chicago,IL
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Shared by Peter Kraus- July 2016
Additional info on deuterium-depletion and cancer:
Defeating Cancer!: The Biological Effect of Deuterium De...
This book is an account of experiments carried out using deuterium-depleted water (Dd-water) and of the human clinical trials underway in Hungary. The most astonis...
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Preventa - Deuterium-depleted drinking water
Preventa - Deuterium-depleted drinking water
The widest spectrum of deuterium depletion
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Qlarivia 25 is a drinking water with a concentration of deuterium of 25±5 ppm (parts per million) obtained by a process patented in Romania and internationally protected.
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P. Kraus
Chicago, IL
recovering Lyme patient
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If you have some information you think can help others in this situation, please send that information, with your permission to share it, to me- Lucy Barnes at AfterTheBite@gmail.com
I will not share your name or other identifying information unless you give permission like the contributors above have done.