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Alpha-gal syndrome (AGS) is a serious, potentially life-threatening allergic condition. AGS is also called alpha-gal allergy, red meat allergy, or tick bite meat allergy. AGS is not caused by an infection. AGS symptoms occur after people eat red meat or are exposed to other products containing alpha-gal.

Alpha measures the excess return above a benchmark for an investment while beta is the measure of volatility, also known as risk. Active investors seek to achieve alpha returns by employing unique strategies."}},{"@type": "Question","name": "What Is a Good Alpha in Finance?","acceptedAnswer": {"@type": "Answer","text": "In finance, specifically in trading and investing, what is considered a good alpha will vary depending on the goal of the investor and the risk tolerance. Generally, a good alpha is one that is greater than zero when adjusted for risk."}},{"@type": "Question","name": "What Does a Negative Alpha Mean in Stocks?","acceptedAnswer": {"@type": "Answer","text": "A negative alpha in stocks means that a stock is underperforming the benchmark when adjusted for risk. If an investor is intending to match or outperform a specific benchmark and their investment portfolio is performing under that rate, then their alpha is negative."}}]}]}] Investing Stocks Bonds ETFs Options and Derivatives Commodities Trading FinTech and Automated Investing Brokers Fundamental Analysis Technical Analysis Markets View All Simulator Login / Portfolio Trade Research My Games Leaderboard Banking Savings Accounts Certificates of Deposit (CDs) Money Market Accounts Checking Accounts View All Personal Finance Budgeting and Saving Personal Loans Insurance Mortgages Credit and Debt Student Loans Taxes Credit Cards Financial Literacy Retirement View All News Markets Companies Earnings CD Rates Mortgage Rates Economy Government Crypto ETFs Personal Finance View All Reviews Best Online Brokers Best Savings Rates Best CD Rates Best Life Insurance Best Personal Loans Best Mortgage Rates Best Money Market Accounts Best Auto Loan Rates Best Credit Repair Companies Best Credit Cards View All Academy Investing for Beginners Trading for Beginners Become a Day Trader Technical Analysis All Investing Courses All Trading Courses View All TradeSearchSearchPlease fill out this field.SearchSearchPlease fill out this field.InvestingInvesting Stocks Bonds ETFs Options and Derivatives Commodities Trading FinTech and Automated Investing Brokers Fundamental Analysis Technical Analysis Markets View All SimulatorSimulator Login / Portfolio Trade Research My Games Leaderboard BankingBanking Savings Accounts Certificates of Deposit (CDs) Money Market Accounts Checking Accounts View All Personal FinancePersonal Finance Budgeting and Saving Personal Loans Insurance Mortgages Credit and Debt Student Loans Taxes Credit Cards Financial Literacy Retirement View All NewsNews Markets Companies Earnings CD Rates Mortgage Rates Economy Government Crypto ETFs Personal Finance View All ReviewsReviews Best Online Brokers Best Savings Rates Best CD Rates Best Life Insurance Best Personal Loans Best Mortgage Rates Best Money Market Accounts Best Auto Loan Rates Best Credit Repair Companies Best Credit Cards View All AcademyAcademy Investing for Beginners Trading for Beginners Become a Day Trader Technical Analysis All Investing Courses All Trading Courses View All EconomyEconomy Government and Policy Monetary Policy Fiscal Policy Economics View All Financial Terms Newsletter About Us Follow Us Table of ContentsExpandTable of ContentsWhat Is Alpha?Understanding AlphaApplying Alpha to InvestingEfficient Market HypothesisSeeking Investment AlphaExample of AlphaAlpha ConsiderationsFAQsThe Bottom LineInvestingQuantitative AnalysisAlpha: What It Means in Investing, With ExamplesBy

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In the United States, the condition usually begins with the bite of the Lone Star tick. The bite transfers a sugar molecule called alpha-gal into the body. In some people, this triggers a reaction from the body's defenses, also called the immune system. It causes mild to severe allergic reactions to red meat, such as beef, pork or lamb. It also can cause reactions to other foods that come from mammals, such as dairy products or gelatins.

The Lone Star tick is found mainly in the southeastern United States. Most cases of alpha-gal syndrome are reported in the south, east and central United States. But the condition appears to be spreading farther north and west. Deer are carrying the Lone Star tick to new parts of the country. Other types of ticks carry alpha-gal molecules in different parts of the world. Alpha-gal syndrome has been diagnosed in parts of Europe, Australia, Asia, South Africa, and South and Central America.

Some people may have alpha-gal syndrome and not know it. There are people who often have serious allergic reactions, also called anaphylactic reactions, for no clear reason. Tests also show that they don't have other food allergies. Researchers think that some of these people may be affected by alpha-gal syndrome.

Avoid tick bites to prevent alpha-gal syndrome. Wear long pants and long-sleeved shirts when you're in wooded, grassy areas. Use bug spray too. Check your whole body for ticks after you spend time outside.

The time delay between eating meat products and getting an allergic reaction may be one reason alpha-gal syndrome was not understood at first. For example, a possible connection between a T-bone steak with dinner and hives at midnight is far from clear.

Researchers think they know the reason for the delayed reaction. They say it's due to the alpha-gal molecules taking longer than other allergens to be digested and enter the system that moves blood through the body.

Most people with alpha-gal syndrome in the U.S. get the condition when a Lone Star tick bites them. Bites from other types of ticks can lead to the condition too. These other ticks cause alpha-gal syndrome in parts of Europe, Australia, Asia, South Africa, and South and Central America.

Experts think the ticks that cause alpha-gal syndrome carry alpha-gal molecules. These come from the blood of the animals they usually bite, such as cows and sheep. When a tick that carries these molecules bites a human, the tick sends alpha-gal into the person's body.

For unknown reasons, some people have a strong immune response to these molecules. The body makes proteins called antibodies. These antibodies target alpha-gal as something the immune system needs to clear out. The response is so strong that people with this allergy can no longer eat red meat. They cannot eat any foods made from mammals without having an allergic reaction. People who get many tick bites over time may develop worse symptoms.

Health care providers don't yet know why some people get alpha-gal syndrome after exposure and others don't. The condition mostly happens in the south, east and central United States. You're at higher risk if you live or spend time in these regions and:

The best way to prevent alpha-gal syndrome is to avoid areas where ticks live. Be careful in wooded, bushy areas with long grass. You can lower your risk of getting alpha-gal syndrome by following some simple tips:

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