Publications (2026-01-27)
2026
1. Seo CW, Lee EY, Oh JS, Choi D*, Urinary extracellular vesicle proteins for biomarker discovery in chronic kidney disease. Kidney Res Clin Pract. 2026 Jan;45(1):36-49.
2. Lee S, Jo E, Lee EY, Choi D*, Proteomics of extracellular vesicles derived from Lactobacillus: Implications in gut immune homeostasis and therapeutic potential. Biomed Pharmacother. 2026 Jan;194:118955.
3. Lee S , Lee Y , Yang H, Choi D*, Song HY*, Optimizing culture conditions for isolation and characterization of extracellular vesicles derived from Lactobacillus crispatus PMC201, Heliyon. 2026 Jan;12 (1)
2025
1. YJ Lee, CW Seo, S Chae, CY Lee, SS Kim, YH Shin, HM Park, YS Gho, S Ryu, SH Lee, D Choi*, Metabolic Reprogramming into a Glycolysis Phenotype Induced by Extracellular Vesicles Derived from Prostate Cancer Cells, Mol Cell Proteomics. 2025 Mar 13;24(4):100944.
2. Lee EC, Choi D, Lee DH, Oh JS. Engineering Exosomes for CNS Disorders: Advances, Challenges, and Therapeutic Potential. Int J Mol Sci. 2025 Mar 28;26(7):3137.
3. Das C, Sepay N, Kim TW, Chae S, Ghosh N, Dumpala M, Choi D, Jeon S, Im J, Biswas G. Recycling Motorcycle Exhaust Soot into Fluorescent Graphene Oxide Quantum Dots for Sensing Ferrocyanide Ions and Bioimaging Cells: A Method for Waste Utilization. ACS Omega. 2025 Mar 31;10(14):14229-14240.
4. 채신원, 정우철, 이윤진, 최동식*, 세포외 소포 연구를 위한 보관, 분리 및 특성 분석 가이드라인, J Digestive Cancer Res. 2025;13(1):9-29.
5. L Adnani, B Meehan, M Kim, D Choi, CE Rudd, Y Riazalhosseini, J Rak, Immune cell infiltration into brain tumor microenvironment is mediated by Rab27-regulated vascular wall integrity, Science Advances. 2025;11(21):eadr6940.
6. D Choi, EY Lee, Standardizing Bacterial Extracellular Vesicle Purification: A Call for Consensus, J Microbiol Biotechnol. 2025 Sep 23;35:e2506011.
7. Y Lee, H Seo, S Lee, D Choi, S Kim, MA Rahim, HY Song, Therapeutic potential of Bacillus sonorensis PMC204 membrane vesicles against drug-resistant Mycobacterium tuberculosis, Med Microbiol Immunol. 2025 Sep 19;214(1):43.
8. Y Lee, SH Lee, D Choi, HS Nam, KD Kim, MH Choi, MK Cho, YJ Lee, Resveratrol Targets Glycolytic Enzymes HK II and PKM2 to Promote Concurrent Apoptotic and Necrotic Cell Death in Malignant Melanoma, Current Issues in Molecular Biology. 2025:47 (12), 1006
2024
1. YJ Lee, C Lee, D Choi, Y Lee, SH Lee, Effect of Soy Isoflavone on Prostate Cancer Cell Apoptosis Through Inhibition of STAT3, ERK, and AKT, Curr Issues Mol Biol 2024 46 (11), 12512-12526
2. D Choi, JG Lee, SH Heo, MK Cho, HS Nam, SH Lee, YJ Lee, Curcumin and Its Potential to Target the Glycolytic Behavior of Lactate-Acclimated Prostate Carcinoma Cells with Docetaxel, Nutrients 2024 16 (24), 4338
2023
1. Won S, Lee C, Bae S, Lee J, Choi D, Kim MG, Song S, Lee J, Kim E, Shin H, Basukala A, Lee TR, Lee DS, Gho YS, Mass-produced gram-negative bacterial outer membrane vesicles activate cancer antigen-specific stem-like CD8+ T cells which enables an effective combination immunotherapy with anti-PD-1, J Extracell Vesicles. 2023 Aug;12(8):e12357.
2. Lee YJ, Chae SW, Choi D*, Monitoring of single extracellular vesicle heterogeneity in cancer progression and therapy, Front Oncol 2023;13
3. Lee YJ, Choi YS, Kim S, Heo JY, Kim DS, Kim KD, Nam SM, Nam HS, Lee SH, Choi D, Cho MK, Overexpression of Dock180 and Elmo1 in Melanoma is Associated with Cell Survival and Migration. Ann Dermatol. 2023 Dec;35(6):439-450.
2022
1. Luu AK, Cadieux M, Wong M, Macdonald R, Jones R, Choi D, Oblak M, Brisson B, Sauer S, Chafitz J, Warshawsky D, Wood GA, Viloria-Petit AM, Proteomic Assessment of Extracellular Vesicles from Canine Tissue Explants as a Pipeline to Identify Molecular Targets in Osteosarcoma: PSMD14/Rpn11 as a Proof of Principle. Int J Mol Sci. 2022 Mar 17;23(6):3256. (2021 IF: 6.208)
2. Daniel P, Meehan B, Sabri S, Jamali F, Sarkaria JN, Choi D, Garnier D, Kitange G, Glennon KI, Paccard A, Karamchandani J, Riazalhosseini Y, Rak J, Abdulkarim B., Detection of temozolomide-induced hypermutation and response to PD-1 checkpoint inhibitor in recurrent glioblastoma, Neurooncol Adv. 2022 May 23;4(1):vdac076.
3. Choi D*, Khan N, Montermini L, Tawil N, Meehan B, Kim DK, Roth FP, Divangahi M, Rak J, Quantitative proteomics and biological activity of extracellular vesicles engineered to express SARS-CoV-2 spike protein, J Extracell Biol. 2022 Oct;1(10):e58.
4. Lee YJ , Seo CW, Lee D, D Choi*, Proteomics of Extracellular Vesicle in Glioblastoma. Brain Tumor Res Treat. 2022 Oct;10(4):207-214.
2021
1. Spinelli C, Tawil N, Adnani L, Rak J*, Choi D*, Extracellular Vesicle Mediated Vascular Pathology in Glioblastoma, Subcell Biochem 2021;97:247-273.
2. Choi D*, Rak J, Gho YS, Isolation of Extracellular Vesicles for Proteomic Profiling, Methods Mol Biol. 2021;2261:193-206.
3. Tawil N, Bassawon R, Meehan B, Nehme A, Montermini L, Gayden T, De Jay N, Spinelli C, Chennakrishnaiah S, Choi D, Adnani L, Zeinieh M, Jabado N, Kleinman CL, Witcher M, Riazalhosseini Y, Key NS, Schiff D, Grover SP, Mackman N, Couturier CP, Petrecca K, Suvà ML, Patel A, Tirosh I, Najafabadi H, Rak J, Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles, Blood Adv. 2021 Mar 23;5(6):1682-1694. (2020 IF: 6.686)
4. Choi D*, Montermini L, Meehan B, Lazaris A, Metrakos P, Rak J, Oncogenic RAS drives the CRAF-dependent extracellular vesicle uptake mechanism coupled with metastasis, J Extracell Vesicles 2021 June 10;10:e12091. (2020 IF: 25.841)
2020
1. Choi D*, Go G, Kim DK, Lee J, Park SM, Di Vizio D, Gho YS*, Quantitative proteomic analysis of trypsin-treated extracellular vesicles to identify the real-vesicular proteins, J Extracell Vesicles 2020 Apr 30;9(1):1757209. (2019 IF: 14.976)
2. Cheng A, Choi D, Lora M, Shum-Tim D, Rak J, Colmegna I, Human multipotent mesenchymal stromal cells cytokine priming promotes RAB27B-regulated secretion of small extracellular vesicles with immunomodulatory cargo, Stem Cell Res Ther. 2020 Dec 14;11(1):539. (2019 IF: 5.116)
3. Chennakrishnaiah S, Tsering T, Gregory Caroline, Tawil N, Spinelli C, Montermini L, Karatzas N, Aprikian S, Choi D, Klewes L, Mai S, Rak J, Extracellular vesicles from genetically unstable, oncogene-driven cancer cells trigger micronuclei formation in endothelial cells, Scientific Reports 2020 May 22;10(1):8532. (2019 IF: 3.998)
4. Luck K, Kim DK, Lambourne L, Spirohn K, Begg BE, Bian W, Brignall R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Coté AG, Daley M, Deimling S, Desbuleux A, Dricot A, Gebbia M, Hardy MF, Kishore N, Knapp JJ, Kovács IA, Lemmens I, Mee MW, Mellor JC, Pollis C, Pons C, Richardson AD, Schlabach S, Teeking B, Yadav A, Babor M, Balcha D, Basha O, Bowman-Colin C, Chin SF, Choi SG, Colabella C, Coppin G, D'Amata C, De Ridder D, De Rouck S, Duran-Frigola M, Ennajdaoui H, Goebels F, Goehring L, Gopal A, Haddad G, Hatchi E, Helmy M, Jacob Y, Kassa Y, Landini S, Li R, van Lieshout N, MacWilliams A, Markey D, Paulson JN, Rangarajan S, Rasla J, Rayhan A, Rolland T, San-Miguel A, Shen Y, Sheykhkarimli D, Sheynkman GM, Simonovsky E, Taşan M, Tejeda A, Tropepe V, Twizere JC, Wang Y, Weatheritt RJ, Weile J, Xia Y, Yang X, Yeger-Lotem E, Zhong Q, Aloy P, Bader GD, De Las Rivas J, Gaudet S, Hao T, Rak J, Tavernier J, Hill DE, Vidal M, Roth FP, Calderwood MA, A reference map of the human binary protein interactome, Nature 2020 Apr;580(7803):402-408. (2019 IF: 42.778)
2019
1. Choi D, Montermini L, Jeong H, Sharma S, Meehan B, Rak J. Mapping subpopulations of cancer cell-derived extracellular vesicles and particles by nano-flow cytometry. ACS Nano. 2019 Sep;13(9):10499-10511. (2019 IF: 14.588)
2. Choi D, Spinelli C, Montermini L and Rak J, Oncogenic regulation of extracellular vesicle proteome and heterogeneity, Proteomics 2019 Jan;19(1-2):e1800169. (2019 IF: 3.254)
3. Go G, Lee J, Choi DS, Kim SS, Gho YS, Extracellular vesicle-mimetic ghost nanovesicles for delivering anti-inflammatory drugs to mitigate gram-negative bacterial outer membrane vesicle-induced systemic inflammatory response syndrome. Advanced Healthcare Materials 2019 Feb;8(4):e1801082. (2019 IF: 7.367)
4. Spinelli C, Adnani L, Choi D, Rak J, Extracellular Vesicles as Conduits of Non-Coding RNA Emission and Intercellular Transfer in Brain Tumors, Non-Coding RNA 2019, 5 (1).
2018
1. Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J, The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells, Mol Cell Proteomics 2018 Oct;17(10):1948-1964. (2019 IF: 4.87)
2. Chennakrishnaiah S, Meehan B, D'Asti E, Montermini L, Lee TH, Karatzas N, Buchanan M, Tawil N, Choi D, Divangahi M, Basik M, Rak J, Leukocytes as a reservoir of circulating oncogenic DNA and regulatory targets of tumor-derived extracellular vesicles. Journal of Thrombosis and Haemostasis 2018 Sep;16(9):1800-1813. (2019 IF: 4.157)
3. Spinelli C, Montermini L, Meehan B, Brisson AR, Tan S, Choi D, Nakano I, Rak J, Molecular subtypes and differentiation programmes of glioma stem cells as determinants of extracellular vesicle profiles and endothelial cell-stimulating activities. Journal of Extracellular Vesicles. 2018 Jul 17;7(1):1490144. (2019 IF: 14.976)
2017
1. Choi D, Lee TH, Spinelli C, Chennakrishnaiah S, D’Asti E, and Rak J, Extracellular vesicle communication pathways as regulatory targets of oncogenic transformation, Seminars in Cell and Developmental Biology 2017 Jan 8. pii: S1084-9521(17)30004-6. (2019 IF: 6.691)
2015
1. Lee J, Kim SH, Choi DS, Lee JS, Kim DK, Go G, Park SM, Kim SH, Shin JH, Chang CL, and Gho YS, Proteomic analysis of extracellular vesicles derived from Mycobacterium tuberculosis, Proteomics 2015 Oct;15(19):3331-7. (Cover Story) (2019 IF: 3.254)
2. Choi DS, Kim DK, Kim YK, Gho YS, Proteomics of extracellular vesicles: Exosomes and ectosomes, Mass Spectrometry Reviews 2015 Jul;34(4):474-90. (Cover Story) (2019 IF: 8.887)
3. Choi DS*, Urinary extracellular vesicles for biomarker source to monitor polycystic kidney disease, Proteomics-Clinical Applications 2015 Jun;9(5-6):447-8. (2019 IF: 2.489)
4. Choi DS and Gho YS, Isolation of extracellular vesicles for proteomic profiling, Methods in Molecular Biology 2015;1295:167-177.
5. Kim DK, Lee J, Kim SR, Choi DS, Yoon YJ, Kim JH, Go G, Nhung D, Hong K, Jang SC, Kim SH, Park KS, Kim OY, Park HT, Seo JH, Aikawa E, Baj-Krzyworzeka M, van Balkom BW, Belting M, Blanc L, Bond V, Bongiovanni A, Borràs FE, Buée L, Buzás EI, Cheng L, Clayton A, Cocucci E, Dela Cruz CS, Desiderio DM, Di Vizio D, Ekström K, Falcon-Perez JM, Gardiner C, Giebel B, Greening DW, Gross JC, Gupta D, Hendrix A, Hill AF, Hill MM, Nolte-'t Hoen E, Hwang DW, Inal J, Jagannadham MV, Jayachandran M, Jee YK, Jørgensen M, Kim KP, Kim YK, Kislinger T, Lässer C, Lee DS, Lee H, van Leeuwen J, Lener T, Liu ML, Lötvall J, Marcilla A, Mathivanan S, Möller A, Morhayim J, Mullier F, Nazarenko I, Nieuwland R, Nunes DN, Pang K, Park J, Patel T, Pocsfalvi G, Del Portillo H, Putz U, Ramirez MI, Rodrigues ML, Roh TY, Royo F, Sahoo S, Schiffelers R, Sharma S, Siljander P, Simpson RJ, Soekmadji C, Stahl P, Stensballe A, Stępień E, Tahara H, Trummer A, Valadi H, Vella LJ, Wai SN, Witwer K, Yáñez-Mó M, Youn H, Zeidler R, Gho YS. EVpedia: A community web portal for extracellular vesicles research. Bioinformatics 2015 Mar 15;31(6):933-9. (2019 IF: 5.610)
6. Jang SC, Kim SR, Yoon YJ, Park KS, Kim JH, Lee J, Kim OY, Choi EJ, Kim DK, Choi DS, Kim YK, Park J, Di Vizio D, Gho YS, In vivo kinetic biodistribution of nano-sized outer membrane vesicles derived from bacteria, Small 2015 Jan;11(4):456-61. (2019 IF: 11.459)
2014
1. Eldh M, Olofsson Bagge R, Lässer C, Svanvik J, Sjöstrand M, Mattsson J, Lindnér P, Choi DS, Gho YS, Lötvall J. MicroRNA in exosomes isolated directly from the liver circulation in patients with metastatic uveal melanoma. BMC Cancer 2014 Dec 16;14(1):962. (2019 IF: 3.15)
2013
1. Choi DS, Lee J, Go G, Kim YK, and Gho YS, Circulating extracellular vesicles in cancer diagnosis and monitoring: an appraisal of clinical potential, Molecular Diagnosis & Therapy 2013 Oct;17(5):265-71.
2. Choi DS, Kim DK, Kim YK, and Gho YS, Proteomics, transcriptomics, and lipidomics of exosomes and ectosomes, Proteomics 2013May;13(10-11):1554-71. (2019 IF: 3.254)
3. Jang SC, Kim OY, Yoon CM, Choi DS, Roh TY, Park J, Nilsson J, Lötvall J, Kim YK, and Gho YS, Bioinspired exosome-mimetic nanovesicles for targeted delivery of chemotherapeutics to malignant tumors, ACS Nano 2013 Sep 24;7(9):7698-710. (2019 IF: 14.588)
4. Park JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, and Kim KP. Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions, Proteomics 2013Jul;13(14):2125-34. (2019 IF: 3.254)
5. Kim DK, Kang B, Kim OY, Choi DS, Lee J, Kim SR, Go G, Yoon YJ, Kim JH, Jang SC, Park KS, Choi EJ, Kim KP, Desiderio DM, Kim YK, Lötvall J, Hwang D, and Gho YS, EVpedia: an integrated database of high-throughput data for systemic analyses of extracellular vesicles, Journal of Extracellular Vesicle 2013 Mar 19;2:20384. (2019 IF: 14.976)
6. Moon HG, Kang CS, Choi JP, Choi DS, Choi HI, Choi YW, Jeon SG, Yoo JY, Jang MH, Gho YS, and Kim YK, Acetyl salicylic acid inhibits Th17 airway inflammation via blockade of IL-6 and IL-17 positive feedback, Experimental & Molecular Medicine 2013 Jan 18;45:e6. (2019 IF: 5.418)
2012
1. Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, KP Kim, and Gho YS, Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells, Journal of Extracellular Vesicles 2012 Sep;1:18704. (2019 IF: 14.976)
2. Choi DS, Yang JS, Choi EJ, Jang SC, Park S, Kim OY, Hwang D, Kim KP, Kim YK, Kim S, and Gho YS, The protein interaction network of extracellular vesicles derived from human colorectal cancer cells, Journal of Proteome Research 2012 Feb;11(2):1144-51. (2019 IF: 4.074)
2011
1. Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, and Gho YS, Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa, Proteomics 2011 Aug;11(16):3424-9. (2019 IF: 3.254)
2. Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, and Gho YS, Proteomic analysis of microvesicles derived from human colorectal cancer ascites, Proteomics 2011Jul;11(13):2745-51. (featured by Research Highlights in Biomarkers Med. (2011) 5(6), 821–822). (2019 IF: 3.254)
2010
1. Moon HG, Kim YS, Choi JP, Choi DS, Yoon CM, Jeon SG, Gho YS, and Kim YK, Aspirin attenuates the anti-inflammatory effects of theophylline via inhibition of cAMP production in mice with non-eosinophilic asthma, Experimental & Molecular Medicine 2010 Jan 31;42(1):47-60. (2019 IF: 5.418)
2009
1. Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, and Gho YS, Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells, BMC Genomics 2009 Nov 25;10:556. (Highly Accessed Article) (2019 IF: 3.594)
2008
1. Lee EY, Choi DS, Kim KP, and Gho YS, Proteomics in gram-negative bacterial outer membrane vesicles, Mass Spectrometry Reviews 2008 Nov-Dec;27(6):535-55. (2019 IF: 8.887)
2007
1. Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, and Gho YS, Proteomic analysis of microvesicles derived from human colorectal cancer cells, Journal of Proteome Research 2007 Dec;6(12):4646-55. (2019 IF: 4.074)
2. Lee EY, Bang JY, Park GW, Choi DS, Kang JS, Kim HJ, Park KS, Lee JO, Kim YK, Kwon KH, Kim KP, and Gho YS, Global proteomic profiling of native outer membrane vesicles derived from Escherichia coli, Proteomics 2007 Sep;7(17):3143-53. (Cover Story) (2019 IF: 3.254)