Warren A Cheung, BSc MSc PhD

張偉麟 (zhang wei lín)

warren DOT cheung AT gmail DOT com

ORCID: orcid.org/0000-0003-0267-7464

NIH BioSketch: https://www.ncbi.nlm.nih.gov/myncbi/warren.cheung@gmail.com/cv/225000/

2401 Gillham Rd

Genomic Medicine Center

Children's Mercy Research Institute

Children's Mercy Kansas City

Kansas City, MO, USA, 64108

Tel: 1.816.234.3000

Academic Background

• Postdoctoral Fellowship, Department of Human Genetics, McGill University Health Centre (October 2016-Sept 2017). Supervisors: Dr. Tomi Pastinen and Dr. Nada Jabado

• Postdoctoral Fellowship, Department of Human Genetics, McGill University and Génome Québec Innovation Centre (May 2013-Sept 2016). Supervisor: Dr. Tomi Pastinen

• Postdoctoral Fellowship, Wasserman Laboratory, Centre for Molecular Medicine and Therapeutics, University of British Columbia (Fall 2012-Spring 2013). Supervisor: Dr. Wyeth Wasserman

• Doctor of Philosophy, Bioinformatics, University of British Columbia. Thesis: Inferring Novel Relationships through Over-Representation Analysis of Medical Subjects in Biomedical Bibliographies. Supervisors: BF Francis Ouellette and Dr. Wyeth Wasserman, (Sept 2005-Nov 2012)

• Master of Science, Computer Science, University of British Columbia. Thesis: Constrained pursuit-evasion problems in the plane. Supervisor: Dr. William Evans, Bioinformatics, and Empirical & Theoretical Algorithmics Laboratory. (Sept 2003-Nov 2005)

• Bachelor of Science, Double Majors in Computer Science and Microbiology, University of British Columbia (Sept 1997-May 2002)

Research Experience

• Bioinformatics Manager, Genomic Medicine Center, Children's Mercy Hospital (Dec 2021-Present)

• Senior Computational Biologist, Center for Pediatric Genomic Medicine, Children's Mercy Hospital (Sept 2017-Dec 2021)

• Postdoctoral Researcher, Department of Human Genetics, McGill University and Génome Québec Innovation Centre, McGill University Health Centre (Oct 2016-Sept 2017)

• Postdoctoral Researcher, Department of Human Genetics, McGill University and Génome Québec Innovation Centre, McGill University Health Centre (May 2013-Sept 2016)

• Postdoctoral Researcher, Wasserman Laboratory, Centre for Molecular Medicine and Therapeutics, University of British Columbia (Fall 2012-Spring 2013).

• Research Rotation, Dr. Wyeth Wasserman, Centre for Molecular Medicine and Therapeutics, University of British Columbia (Fall 2006). Finding Overrepresented Promoter Elements for Purkinje cell specific expression

• Research Rotation, BF Francis Ouellette, University of British Columbia Bioinformatics Centre, University of British Columbia (Summer 2006). Mapping the Protein Interaction Space.

• Research Rotation, Dr. Artem Cherkasov, Infectious Diseases Division, Faculty of Medicine, University of British Columbia (Spring 2006). Predicting Host Defense Peptide Activity from Computed Sequence-based Descriptors.

• Research Assistant, Dr. Holger Hoos, Department of Computer Science, University of British Columbia. Touchscreen Wayfinding Kiosk. (Sept 2004-Apr 2005)

• Research Assistant, Dr. William Evans, Department of Computer Science, University of British Columbia. Code Compaction on the ARM processor. (May 2002-Aug 2003)

Supervisory and Teaching Experience

• STAT 540 - Statistical Methods for High Dimensional Biology - Course Development, Department of Psychiatry, University of British Columbia. Sept-Dec 2010.

• Graduate Student Instructional Skills Workshop, Centre for Teaching, Learning and Technology, University of British Columbia. (Aug-Sept 2010)

• Mentor, Canadian Gene Cure Foundation's Gene Researcher for a Week 2009

• Teaching Assistant, Department of Computer Science, University of British Columbia.

  • CPSC 445 - Algorithms for Bioinformatics, Jan-Apr 2009.

  • CPSC 304 - Introduction to Relational Databases. Jun-Jul 2005, Jan-Apr 2004.

  • CPSC 314 - Computer Graphics. May-Jun 2005.

  • CPSC 320 - Intermediate Algorithm Design and Analysis. Jun-Jul 2004.

  • CPSC 121 - Models of Computation. May-Jun 2004.

  • CPSC 420 - Advanced Algorithms. Sept-Dec 2003

  • CPSC 220 - Introduction to Discrete Structures. Jan-Apr 2002.

  • CPSC 315 - Introduction to Operating Systems. Sept-Dec 2002.

Scholarship Awards, Distinctions and Credentials

• Postdoctoral Fellowship Award (Declined due to existing funding). Research Institute of the McGill University Health Centre. 2014-2015

• Postdoctoral Training Award, Fonds de Recherche du Québec - Santé. 2014-2016.

• Four Year Doctoral Fellowship Award, University of British Columbia. 2009-2010.

• MSFHR Senior Graduate Studentship, Michael Smith Foundation for Health Research, Canada. 2008-2010.

• NSERC Postgraduate Scholarship D3, National Sciences and Engineering Research Council of Canada, Canada. 2007-2010.

• Strategic Training Program in Bioinformatics Graduate Award, Canadian Institutes for Health Research/Michael Smith Foundation for Health Research, Canada. 2005-2007.

• Undergraduate Student Research Award, Natural Sciences and Engineering Research Council of Canada, Canada. 2002-2003.

• Dean's Honour List, University of British Columbia, Canada, 1997-1998, 2000-2001, 2001-2002.

• Outstanding Student Initiative Scholarship, University of British Columbia, Canada, 1997-2000.

• Passport to Education, British Columbia Government, 1997.

Publications

1. Smail C, Ge B, Keever-Keigher MR, Schwendinger-Schreck C, Cheung WA, Johnston JJ, Barrett C; Genomic Answers for Kids Consortium; Feldman K, Cohen ASA, Farrow EG, Thiffault I, Grundberg E, Pastinen T. Complex trait associations in rare diseases and impacts on Mendelian variant interpretation. Nat Commun. 2024 Sep 18;15(1):8196. doi: 10.1038/s41467-024-52407-1. PMID: 39294130.  medRxiv 2024 Jan 11 doi:10.1101/2024.01.10.24301111

2. David Pellerin, Giulia F. Del Gobbo, Madeline Couse, Egor Dolzhenko, Sathiji K. Nageshwaran, Warren A. Cheung, Isaac R. L. Xu, Marie-Josée Dicaire, Guinevere Spurdens, Gabriel Matos-Rodrigues, Igor Stevanovski, Carolin K. Scriba, Adriana Rebelo, Virginie Roth, Marion Wandzel, Céline Bonnet, Catherine Ashton, Aman Agarwal, Cyril Peter, Dan Hasson, Nadejda M. Tsankova, Ken Dewar, Phillipa J. Lamont, Nigel G. Laing, Mathilde Renaud, Henry Houlden, Matthis Synofzik, Karen Usdin, Andre Nussenzweig, Marek Napierala, Zhao Chen, Hong Jiang, Ira W. Deveson, Gianina Ravenscroft, Schahram Akbarian, Michael A. Eberle, Kym M. Boycott, Tomi Pastinen, All of Us Research Program Long Read Working Group, Bernard Brais, Stephan Zuchner & Matt C. Danzi. A common flanking variant is associated with enhanced stability of the FGF14-SCA27B repeat locus. Nat Genet (2024). doi:10.1038/s41588-024-01808-5 (Preprint PMID: 37425777 PMCID: PMC10327060 DOI: 10.1101/2023.05.11.540430)

3. Cristian Groza, Carl Schwendinger-Schreck, Warren A. Cheung, Emily G. Farrow, Isabelle Thiffault, Juniper Lake, William B. Rizzo, Gilad Evrony, Tom Curran, Guillaume Bourque, Tomi Pastinen.  Pangenome graphs improve the analysis of structural variants in rare genetic diseases. Nature Communications 15, 657 (2024). doi: 10.1038/s41467-024-44980-2 medRxiv 2023 Jun 11. doi: 10.1101/2023.05.31.23290808

4. LeMaster C, Schwendinger-Schreck C, Ge B, Cheung WA, McLennan R, Johnston JJ, Pastinen T, Smail C. Mapping structural variants to rare disease genes using long-read whole genome sequencing and trait-relevant polygenic scores. medRxiv. 2024 May 16. doi: 10.1101/2024.03.15.24304216 PMID: 38562793.

5. Xiaojian Shao, Sophie Le Fur, Warren Cheung, Marie-Pierre Belot, Kevin Perge, Natacha Bouhours-Nouet, Candace Bensignor, Lucie Levaillant, Bing Ge, Tony Kwan, Mark Lathrop, Tomi Pastinen, Pierre Bougnères. CpG methylation changes associated with hyperglycemia in type 1 diabetes occur at angiogenic glomerular and retinal gene loci. Research Square 10 January 2024, PREPRINT (Version 1) doi: 10.21203/rs.3.rs-3845834/v1

6. Dolzhenko E, English A, Dashnow H, De Sena Brandine G, Mokveld T, Rowell WJ, Karniski C, Kronenberg Z, Danzi MC, Cheung WA, Bi C, Farrow E, Wenger A, Chua KP, Martínez-Cerdeño V, Bartley TD, Jin P, Nelson DL, Zuchner S, Pastinen T, Quinlan AR, Sedlazeck FJ, Eberle MA. Characterization and visualization of tandem repeats at genome scale. Nature Biotechnology 2024 Jan 2. doi: 10.1038/s41587-023-02057-3. PMID: 38168995.

7. Kaela M. Varberg, Esteban M. Dominguez, Boryana Koseva, Joseph M. Varberg, Ross P. McNally, Ayelen Moreno-Irusta, Emily R. Wesley, Khursheed Iqbal, Warren A. Cheung, Carl Schwendinger-Schreck, Craig Smail, Hiroaki Okae, Takahiro Arima, Michael Lydic, Kristin Holoch, Courtney Marsh, Michael J. Soares & Elin Grundberg. Extravillous trophoblast cell lineage development is associated with active remodeling of the chromatin landscape. Nature Communications 14, 4826 (2023). doi: 10.1038/s41467-023-40424-5 PMID: 37563143; PMCID: PMC10415281; medRxiv 2022 May 26 doi:10.1101/2022.05.25.22275520

8. Cheung WA, Johnson AF, Rowell WJ, Farrow E, Hall R, Cohen ASA, Means JC, Zion TN, Portik DM, Saunders CT, Koseva B, Bi C, Truong TK, Schwendinger-Schreck C, Yoo B, Johnston JJ, Gibson M, Evrony G, Rizzo WB, Thiffault I, Younger ST, Curran T, Wenger AM, Grundberg E, Pastinen T. Direct haplotype-resolved 5-base HiFi sequencing for genome-wide profiling of hypermethylation outliers in a rare disease cohort. Nat Commun. 2023 May 29;14(1):3090. doi: 10.1038/s41467-023-38782-1. PMID: 37248219; PMCID: PMC10226990; medRxiv 2022 Sept 16 doi:10.1101/2022.09.12.22279739

9. Fu Q, Cheung WA, Majnik AV, Ke X, Pastinen T, Lane RH. Adverse Maternal Environments Perturb Hepatic DNA Methylome and Transcriptome Prior to the Adult-Onset Non-Alcoholic Fatty Liver Disease in Mouse Offspring. Nutrients. 2023; 15(9):2167. doi:10.3390/nu15092167

10. Tricia N. Zion, Courtney D. Berrios, Ana S.A. Cohen, Lauren Bartik, Laura A. Cross, Kendra L. Engleman, Emily A. Fleming, Randi N. Gadea, Susan S. Hughes, Janda L. Jenkins, Jennifer Kussmann, Caitlin Lawson, Caitlin Schwager, Meghan E. Strenk, Holly Welsh, Eric T. Rush, Shivarajan M. Amudhavalli, Bonnie R. Sullivan, Dihong Zhou, Jennifer L. Gannon, Bryce A. Heese, Riley Moore, Emelia Boillat, Rebecca L. Biswell, Daniel A. Louiselle, Laura M.B. Puckett, Shanna Beyer, Shelby H. Neal, Victoria Sierant, Macy McBeth, Bradley Belden, Adam M. Walter, Margaret Gibson, Warren A. Cheung, Jeffrey J. Johnston, Isabelle Thiffault, Emily G. Farrow, Elin Grundberg, Tomi Pastinen. Insurance denials and diagnostic rates in a pediatric genomic research cohort. Genetics in Medicine, 2023 Jan 28.  doi:10.1016/j.gim.2023.100020

11. Ana S.A. Cohen, Emily G. Farrow, Ahmed T. Abdelmoity, Joseph T. Alaimo, Shivarajan M. Amudhavalli, John T. Anderson, Lalit Bansal, Lauren Bartik, Primo Baybayan, Bradley Belden, Courtney D. Berrios, Rebecca L. Biswell, Pawel Buczkowicz, Orion Buske, Shreyasee Chakraborty, Warren A. Cheung, Keith A. Coffman, Ashley M. Cooper, Laura A. Cross, Tom Curran, Thuy Tien T. Dang, Mary M. Elfrink, Kendra L. Engleman, Erin D. Fecske, Cynthia Fieser, Keely Fitzgerald, Emily A. Fleming, Randi N. Gadea, Jennifer L. Gannon, Rose N. Gelineau-Morel, Margaret Gibson, Jeffrey Goldstein, Elin Grundberg, Kelsee Halpin, Brian S. Harvey, Bryce A. Heese, Wendy Hein, Suzanne M. Herd, Susan S. Hughes, Mohammed Ilyas, Jill Jacobson, Janda L. Jenkins, Shao Jiang, Jeffrey J. Johnston, Kathryn Keeler, Jonas Korlach, Jennifer Kussmann, Christine Lambert, Caitlin Lawson, Jean-Baptiste Le Pichon, James Steven Leeder, Vicki C. Little, Daniel A. Louiselle, Michael Lypka, Brittany D. McDonald, Neil Miller, Ann Modrcin, Annapoorna Nair, Shelby H. Neal, Christopher M. Oermann, Donna M. Pacicca, Kailash Pawar, Nyshele L. Posey, Nigel Price, Laura M.B. Puckett, Julio F. Quezada, Nikita Raje, William J. Rowell, Eric T. Rush, Venkatesh Sampath, Carol J. Saunders, Caitlin Schwager, Richard M. Schwend, Elizabeth Shaffer, Craig Smail, Sarah Soden, Meghan E. Strenk, Bonnie R. Sullivan, Brooke R. Sweeney, Jade B. Tam-Williams, Adam M. Walter, Holly Welsh, Aaron M. Wenger, Laurel K. Willig, Yun Yan, Scott T. Younger, Dihong Zhou, Tricia N. Zion, Isabelle Thiffault, Tomi Pastinen. Genomic answers for children: Dynamic analyses of >1000 pediatric rare disease genomes. Genetics in Medicine, June 2022. doi:10.1016/j.gim.2022.02.007 PMID: 35305867 (medRxiv. 2021 Oct 12. doi:10.1101/2021.10.07.21264628)

12. Xiaojian Shao, Catherine Le Stunff, Warren Cheung, Tony Kwan, Mark Lathrop, Tomi Pastinen, Pierre Bougnères. Differentially methylated CpGs in response to growth hormone administration in children with idiopathic short stature. Clin Epigenetics, 2022 May 18;14(1):65. doi: 10.1186/s13148-022-01281-z PMID: 35585611 FULL TEXT

13. Kaela M. Varberg, Boryana Koseva, Khursheed Iqbal, Jinchu Vijay, Rebecca Biswell, Margaret Gibson, Warren A. Cheung, Joseph M. Varberg, Hiroaki Okae, Takahiro Arima, Michael J. Soares, Elin Grundberg. (2021). Dynamic Regulation of the Chromatin Landscape during Human Extravillous Trophoblast Cell Lineage Development. Placenta. 112. e16-e17. 10.1016/j.placenta.2021.07.055. 

14. Konner Winkley, Dithi Banerjee, Todd Bradley, Boryana Koseva, Warren A. Cheung, Rangaraj Selvarangan, Tomi Pastinen & Elin Grundberg. Immune cell residency in the nasal mucosa may partially explain respiratory disease severity across the age range. Scientific Reports 11, 15927 (2021). doi:10.1038/s41598-021-95532-3 FULL TEXT

15. Winkley K, Koseva B, Banerjee D, Cheung W, Selvarangan R, Pastinen T, Grundberg E. High-resolution epigenome analysis in nasal samples derived from children with respiratory viral infections reveals striking changes upon SARS-CoV-2 infection. medRxiv. 2021 Mar 11;2021.03.09.21253155. doi:10.1101/2021.03.09.21253155 PMID 33758880 FULL TEXT

16. Tricia Zion, Daniel Louiselle, Rebecca Biswell, Laura Puckett, Nyshele Posey, Shelby Neal, Mary Elfrink, Brittany McDonald, Alexandra Greathous, Bradley Belden, Suzanne Herd, Adam Walter, Margaret Gibson, Warren Cheung, Jeffrey Johnston, Ana Cohen, Isabelle Thiffault, Emily Farrow, Neil Miller, Tomi Pastinen, Elin Grundberg. Exploration of genetic variation beyond leukocyte-derived germline DNA in a pediatric rare disease cohort. Molecular Genetics and Metabolism. Volume 132, Supplement 1, April 2021, Page S285. doi:10.1016/S1096-7192(21)00526-6

17. Isabelle Thiffault, Emily Farrow, Ana Cohen, Tricia Zion, Shelby Neal, Warren Cheung, Jeffrey Johnston, Neil Miller, Margaret Gibson,Adam Walter, Laura Puckett, Nyshele Posey, Annapoorna Nair, Brittany McDonald, Mary Elfrink, Suzanne Herd, Tomi Pastinen. Retrospective analysis of NGS data in pediatric genetic cohort: detection of rare variants that may impact influenza and COVID-19 infection. Molecular Genetics and Metabolism. Volume 132, Supplement 1, April 2021, Page S285. doi:10.1016/S1096-7192(21)00419-4 FULL TEXT

18. Mingju Cao, Xiaojian Shao, Peter Chan, Warren Cheung, Tony Kwan, Tomi Pastinen & Bernard Robaire. High-resolution analyses of human sperm dynamic methylome reveal thousands of novel age-related epigenetic alterations. Clinical Epigenetics. Dec 2020. 12(1):192. doi:10.1186/s13148-020-00988-1 PMID 33317634 FULL TEXT

19. Madore AM, Pain L, Boucher-Lafleur AM, Morin A, Meloche J, Simon MM, Ge B, Kwan T, Cheung WA, Pastinen T, Laprise C. Asthma-associated polymorphisms in 17q12-21 locus modulate methylation and gene expression of GSDMA in naïve CD4+ T cells. Journal of Genetics and Genomics. Mar 2020. S1673-8527(20)30064-3. doi:10.1016/j.jgg.2020.03.002  PMID 32312674

20. Jinchu Vijay, Marie-Frédérique Gauthier, Rebecca L. Biswell, Daniel A. Louiselle, Jeffrey J. Johnston, Warren A. Cheung, Bradley Belden, Albena Pramatarova, Laurent Biertho, Margaret Gibson, Marie-Michelle Simon, Haig Djambazian, Alfredo Staffa, Guillaume Bourque, Anita Laitinen, Johanna Nystedt, Marie-Claude Vohl, Jason D. Fraser, Tomi Pastinen, André Tchernof & Elin Grundberg. Single-cell analysis of human adipose tissue identifies depot- and disease-specific cell types. Nature Metabolism. Dec 2019. doi:10.1038/s42255-019-0152-6  PMID 32066997 FULL TEXT

21. Ashot S. Harutyunyan, Brian Krug, Haifen Chen, Simon Papillon-Cavanagh, Michele Zeinieh, Nicolas De Jay, Shriya Deshmukh, Carol C. L. Chen, Jad Belle, Leonie G. Mikael, Dylan M. Marchione, Rui Li, Hamid Nikbakht, Bo Hu, Gael Cagnone, Warren A. Cheung, Abdulshakour Mohammadnia, Denise Bechet, Damien Faury, Melissa K McConechy, Manav Pathania, Siddhant U. Jain, Benjamin Ellezam, Alexander G. Weil, Alexandre Montpetit, Paolo Salomoni, Tomi Pastinen, Chao Lu, Peter W. Lewis, Benjamin A. Garcia, Claudia L. Kleinman, Nada Jabado & Jacek Majewski. H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis. Nature Communications. 10:1262. Mar 2019. doi:10.1038/s41467-019-09140-x PMID 30890717 FULL TEXT

22. Fiona Allum, Åsa K. Hedman, Xiaojian Shao, Warren A. Cheung, Jinchu Vijay, Frédéric Guénard, Tony Kwan, Marie-Michelle Simon, Bing Ge, Cristiano Moura, Elodie Boulier, Lars Rönnblom, Sasha Bernatsky, Mark Lathrop, Mark I. McCarthy, Panos Deloukas, André Tchernof, Tomi Pastinen, Marie-Claude Vohl & Elin Grundberg. Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements. Nature Communications. 10:1209. Mar 2019. doi:10.1038/s41467-019-09184-z PMID 30872577 FULL TEXT

23. Anita M. Quintana, Hung-Chun Yu, Alison Brebner, Mihaela Pupavac, Elizabeth A. Geiger, Abigail Watson,Victoria L. Castro, Warren Cheung, Shu-Huang Chen, David Watkins, Tomi Pastinen, Flemming Skovby, Bruce Appel, David S. Rosenblatt, Tamim H. Shaikh. Mutations in THAP11 cause an inborn error of cobalamin metabolism and developmental abnormalities. Human Molecular Genetics. Apr 2017. doi:10.1093/hmg/ddx157 PMID 28449119

24. Warren A. Cheung, Xiaojian Shao, Andréanne Morin, Valérie Siroux, Tony Kwan, Bing Ge, Dylan Aïssi, Lu Chen, Louella Vasquez, Fiona Allum, Frédéric Guénard, Emmanuelle Bouzigon, Marie-Michelle Simon, Elodie Boulier, Adriana Redensek, Stephen Watt, Avik Datta, Laura Clarke, Paul Flicek, Daniel Mead, Dirk S. Paul, Stephan Beck, Guillaume Bourque, Mark Lathrop, André Tchernof, Marie-Claude Vohl, Florence Demenais, Isabelle Pin, Kate Downes, Hendrick G. Stunnenberg, Nicole Soranzo, Tomi Pastinen, Elin Grundberg. Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome. Genome Biology. Vol 18, pp. 50. Mar 2017. doi:10.1186/s13059-017-1173-7 PMID 28283040

25. Simone Ecker, Lu Chen, Vera Pancaldi, Frederik O. Bagger, José María Fernández, Enrique Carrillo de Santa Pau, David Juan, Alice L. Mann, Stephen Watt, Francesco Paolo Casale, Nikos Sidiropoulos, Nicolas Rapin, Angelika Merkel, BLUEPRINT Consortium, Hendrik G. Stunnenberg, Oliver Stegle, Mattia Frontini, Kate Downes, Tomi Pastinen, Taco W. Kuijpers, Daniel Rico, Alfonso Valencia, Stephan Beck, Nicole Soranzo and Dirk S. Paul. Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. Genome Biology. Vol. 18, pp. 18. Jan 2017. doi:10.1186/s13059-017-1156-8 PMID 26185018

26. Dirk S. Paul, Andrew E. Teschendorff, Mary A. N. Dang, Robert Lowe, Mohammed I. Hawa, Simone Ecker, Stephanie Cunningham, Alexandra R. Fouts, Anita Ramelius, Frances Burden, Samantha Farrow, Sophia Rowlston, Karola Rehnstrom, Mattia Frontini, Kate Downes, Stephan Busche, Warren Cheung, Bing Ge, Marie-Michelle Simon, David Bujold, Tony Kwan, Guillaume Bourque, Avik Datta, Ernesto Lowy, Laura Clarke, Paul Flicek, Emanuele Libertini, Simon Heath, Marta Gut, Ivo G. Gut, Willem H. Ouwehand, Tomi Pastinen, Nicole Soranzo, Sabine E. Hofer, Beate Karges, Thomas Meissner, Bernhard O. Boehm, Corrado Cilio, Helena Elding Larsson, Åke Lernmark, Andrea K. Steck, Vardhman K. Rakyan, Stephan Beck & R. David Leslie. Increased DNA methylation variability in type 1 diabetes across three immune effector cell types. Nature Communications. Vol. 7, article 13555. Nov. 2016. doi:10.1038/ncomms13555 PMID 27898055

27. Lu Chen, Bing Ge, Francesco Paolo Casale, Louella Vasquez, Tony Kwan, Diego Garrido-Martín, Stephen Watt, Ying Yan, Kousik Kundu, Simone Ecker, Avik Datta, David Richardson, Frances Burden, Daniel Mead, Alice L. Mann, Jose Maria Fernandez, Sophia Rowlston, Steven P. Wilder, Samantha Farrow, Xiaojian Shao, John J. Lambourne, Adriana Redensek, Cornelis A. Albers, Vyacheslav Amstislavskiy, Sofie Ashford, Kim Berentsen, Lorenzo Bomba, Guillaume Bourque, David Bujold, Stephan Busche, Maxime Caron, Shu-Huang Chen, Warren Cheung, Oliver Delaneau, Emmanouil T. Dermitzakis, Heather Elding, Irina Colgiu, Frederik O. Bagger, Paul Flicek, Ehsan Habibi, Valentina Iotchkova, Eva Janssen-Megens, Bowon Kim, Hans Lehrach, Ernesto Lowy, Amit Mandoli, Filomena Matarese, Matthew T. Maurano, John A. Morris, Vera Pancaldi, Farzin Pourfarzad, Karola Rehnstrom, Augusto Rendon, Thomas Risch, Nilofar Sharifi, Marie-Michelle Simon, Marc Sultan, Alfonso Valencia, Klaudia Walter, Shuang-Yin Wang, Mattia Frontini, Stylianos E. Antonarakis, Laura Clarke, Marie-Laure Yaspo, Stephan Beck, Roderic Guigo, Daniel Rico, Joost H.A. Martens, Willem H. Ouwehand, Taco W. Kuijpers, Dirk S. Paul, Hendrik G. Stunnenberg, Oliver Stegle, Kate Downes, Tomi Pastinen, Nicole Soranzo. Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. Cell. Vol. 167, Issue 5, pp. 1398–1414.e24. Nov. 2016. doi:10.1016/j.cell.2016.10.026 PMID 27863251

28. Mihaela Pupavac, David Watkins, Francis Petrella, Somayyeh Fahiminiya, Alexandre Janer, Warren Cheung, Anne-Claude Gingras, Tomi Pastinen, Joseph Muenzer, Jacek Majewski, Eric A. Shoubridge, David S. Rosenblatt. Inborn Error of Cobalamin Metabolism Associated with the Intracellular Accumulation of Transcobalamin-Bound Cobalamin and Mutations in ZNF143, Which Codes for a Transcriptional Activator. Human Mutation. Vol. 37, Issue 9, pp. 976–982. Sept. 2016. doi:10.1002/humu.23037 PMID 27349184

29. Stephan Busche, Xiaojian Shao, Maxime Caron, Tony Kwan, Fiona Allum, Warren A. Cheung, Bing Ge, Susan Westfall, Marie-Michelle Simon, The Multiple Tissue Human Expression Resource, Amy Barrett, Jordana T. Bell, Mark I. McCarthy, Panos Deloukas, Mathieu Blanchette, Guillaume Bourque, Timothy D. Spector, Mark Lathrop, Tomi Pastinen and Elin Grundberg. Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation. Genome Biology. Vol. 16, Issue 290. Dec. 2015. doi:10.1186/s13059-015-0856-1 PMID 26699896

30. Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A, Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C, Kleinman A, Styrkarsdottir U, Liu CT, Uggla C, Evans DS, Nielson CM, Walter K, Pettersson-Kymmer U, McCarthy S, Eriksson J, Kwan T, Jhamai M, Trajanoska K, Memari Y, Min J, Huang J, Danecek P, Wilmot B, Li R, Chou WC, Mokry LE, Moayyeri A, Claussnitzer M, Cheng CH, Cheung W, Medina-Gómez C, Ge B, Chen SH, Choi K, Oei L, Fraser J, Kraaij R, Hibbs MA, Gregson CL, Paquette D, Hofman A, Wibom C, Tranah GJ, Marshall M, Gardiner BB, Cremin K, Auer P, Hsu L, Ring S, Tung JY, Thorleifsson G, Enneman AW, van Schoor NM, de Groot LC, van der Velde N, Melin B, Kemp JP, Christiansen C, Sayers A, Zhou Y, Calderari S, van Rooij J, Carlson C, Peters U, Berlivet S, Dostie J, Uitterlinden AG, Williams SR, Farber C, Grinberg D, LaCroix AZ, Haessler J, Chasman DI, Giulianini F, Rose LM, Ridker PM, Eisman JA, Nguyen TV, Center JR, Nogues X, Garcia-Giralt N, Launer LL, Gudnason V, Mellström D, Vandenput L, Amin N, van Duijn CM, Karlsson MK, Ljunggren Ö, Svensson O, Hallmans G, Rousseau F, Giroux S, Bussière J, Arp PP, Koromani F, Prince RL, Lewis JR, Langdahl BL, Pernille Hermann A, Jensen JB, Kaptoge S, Khaw KT, Reeve J, Formosa MM, Xuereb-Anastasi A, Åkesson K, McGuigan FE, Garg G, Olmos JM, Zarrabeitia MT, Riancho JA, Ralston SH, Alonso N, Jiang X, Goltzman D, Pastinen T, Grundberg E, Gauguier D, Orwoll ES, Karasik D, Davey-Smith G; AOGC Consortium, Smith AV, Siggeirsdottir K, Harris TB, Carola Zillikens M, van Meurs JB, Thorsteinsdottir U, Maurano MT, Timpson NJ, Soranzo N, Durbin R, Wilson SG, Ntzani EE, Brown MA, Stefansson K, Hinds DA, Spector T, Adrienne Cupples L, Ohlsson C, Greenwood CM; UK10K Consortium, Jackson RD, Rowe DW, Loomis CA, Evans DM, Ackert-Bicknell CL, Joyner AL, Duncan EL, Kiel DP, Rivadeneira F, Richards JB. Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture. Nature. Vol. 526, Issue 7571, pp. 112-7. Oct. 2015. doi:10.1038/nature14878 PMID 26367794

31. Stephanie O. M. Dyke, Warren A. Cheung, Yann Joly, Ole Ammerpohl, Pavlo Lutsik, Mark A. Rothstein, Maxime Caron, Stephan Busche, Guillaume Bourque, Lars Rönnblom, Paul Flicek, Stephan Beck, Martin Hirst, Henk Stunnenberg, Reiner Siebert, Jörn Walter and Tomi Pastinen. Epigenome data release: a participant-centered approach to privacy protection. Genome Biology, Vol. 16, pp. 142 . July 2015. doi:10.1186/s13059-015-0723-0 PMID 26185018

32. Yann Joly, Stephanie OM Dyke, Warren A Cheung, Mark A. Rothstein, & Tomi Pastinen. Risk of re-identification of epigenetic methylation data: a more nuanced response is needed. Clinical Epigenetics, Vol. 7, Issue 1, pp. 7–9. April 2015. doi:10.1186/s13148-015-0079-z PMID 25904991

33. Warren A Cheung, BF Francis Ouellette, and Wyeth W Wasserman. Compensating for Literature Annotation Bias when Predicting Novel Drug-Disease Relationships through Medical Subject Heading Over-representation Profile (MeSHOP) Similarity. BMC Medical Genomics. Vol. 6, Suppl. 2, S3. May 2013. doi:10.1186/1755-8794-6-S2-S3 PMID 23819887

34. Warren A Cheung, BF Francis Ouellette, and Wyeth W Wasserman. Inferring novel gene-disease associations using medical subject heading over-representation profiles. Genome Medicine. Vol. 4, Issue 9, pp. 75. Sept 2012. doi:10.1186/gm376 PMID 23021552

35. Warren A Cheung, BF Francis Ouellette, and Wyeth W Wasserman. Quantitative biomedical annotation using medical subject heading over-representation profiles (MeSHOPs). BMC Bioinformatics. Vol. 13, pp. 249. Sept 2012. doi:10.1186/1471-2105-13-249 PMID 23017167

36. W. Cheung. Inferring novel relationships through over-representation analysis of medical subjects in biomedical bibliographies. Ph.D. thesis, Bioinformatics Program, University of British Columbia. August 2012. http://hdl.handle.net/2429/43073 doi:10.14288/1.0073074

37. Dimas Yusuf, Stefanie L Butland, Magdalena I Swanson, Eugene Bolotin, Amy Ticoll, Warren A Cheung, Xiao YC Zhang, Christopher TD Dickman, Debra L Fulton, Jonathan S Lim, Jake M Schnabl, Oscar HP Ramos, Mireille Vasseur-Cognet, Charles N de Leeuw, Elizabeth M Simpson, Gerhart U Ryffel, Eric W-F Lam, Ralf Kist, Miranda SC Wilson, Raquel Marco-Ferreres, Jan J Brosens, Leonardo L Beccari, Paola Bovolenta, Berenice A Benayoun, Lara J Monteiro, Helma DC Schwenen, Lars Grontved, Elizabeth Wederell, Susanne Mandrup, Reiner A Veitia et al. The Transcription Factor Encyclopedia. Genome Biology. Vol. 13, Issue 3, pp. R24. March 2012. doi:10.1186/gb-2012-13-3-r24 PMID 22458515

38. Fjell, C. D., Jenssen, H., Cheung, W. A., Hancock, R. E. W. and Cherkasov, A. , Optimization of Antibacterial Peptides by Genetic Algorithms and Cheminformatics. Chemical Biology & Drug Design. Volume 77, Issue 1, pages 48–56, January 2011. doi:10.1111/j.1747-0285.2010.01044.x PMID 20942839

39. W. A. Cheung. Optimising Locality-Sensitive Hashing on Sequences in the Context of Motif Finding. In Proceedings of the Canadian Student Conference on Biomedical Computing and Engineering (CSCBCE) 2010. May 2010.

40. W. Cheung, G. Hamarneh. n-SIFT: n-Dimensional Scale Invariant Feature Transform. IEEE Transactions on Image Processing. Volume 18, Issue 9, Sept. 2009. pp:2012 - 2021. doi:10.1109/TIP.2009.2024578 PMID 19502129

41. C. Fjell, H. Jenssen, K.Hilpert, W.Cheung. R.Hancock, A.Cherkasov. P92 Optimization of antibacterial peptides by genetic algorithms and QSAR. International Journal of Antimicrobial Agents. Abstracts from the 26th International Congress of Chemotherapy and Infection, page S56. July 2009. doi:10.1016/S0924-8579(09)70311-5 .

42. Christopher D. Fjell, Håvard Jenssen, Kai Hilpert, Warren A. Cheung, Nelly Panté, Robert E.W. Hancock and Artem Cherkasov. Identification of Novel Antibacterial Peptides by Chemoinformatics and Machine Learning. Journal of Medicinal Chemistry, 2009. doi:10.1021/jm8015365 PMID 19296598

43. Warren A Cheung, Francis BF Ouellette, Wyeth W. Wasserman. Mapping Biomedical Literature Annotations to Extract Gene-Disease Associations. In Proceedings of the Canadian Student Conference on Biomedical Computing (CSCBC) 2008.

44. Kemmer D, Podowski RM, Yusuf D, Brumm J, Cheung W, Wahlestedt C, Lenhard B, Wasserman WW. (2008) Gene Characterization Index: Assessing the Depth of Gene Annotation. Public Library of Science (PLoS) ONE 3(1): e1440 doi:10.1371/journal.pone.0001440 PMID 18213364

45. Warren Cheung and Ghassan Hamarneh. Scale Invariant Feature Transform for n-Dimensional Images (n-SIFT). The Insight Journal, 2007 July - December, December 2007. Over 2400 downloads as of Oct. 2013 from http://hdl.handle.net/1926/1321 or http://insight-journal.org/browse/publication/207 .

46. Warren Cheung and William Evans. Pursuit-Evasion Voronoi Diagrams in L1. In Proceedings of the 4th International Symposium on Voronoi Diagrams in Science and Engineering (ISVD) 2007. pp.58-65.

47. W. Cheung and G. Hamarneh. n-SIFT: n-Dimensional Scale Invariant Feature Transform for Matching Medical Images. In Proceedings of the Fourth IEEE International Symposium on Biomedical Imaging (ISBI) 2007. pp.720-723. doi:10.1109/ISBI.2007.356953 Over 900 downloads as of Oct. 2013 from the SFU MIAL project page.

48. W. Cheung. Constrained pursuit-evasion problems in the plane. Master’s thesis, Department of Computer Science, University of British Columbia, September 2005. http://hdl.handle.net/2429/16494 doi:10.14288/1.0051143

49. Mike Klaas, Tristram Southey, and Warren Cheung. 2005. Particle-Based Communication Among Game Agents. In Proceedings of the First Artificial Intelligence and Interactive Digital Entertainment (AIIDE) Conference,pp.75-80. Menlo Park, Calif. AAAI Press.

50. W. Cheung, J. Moses and W. Evans. Predicated Instructions for Code Compaction. In the Proceedings for the 7th International Workshop on Software and Compilers for Embedded Systems (SCOPES) 2003. Lecture Notes in Computer Science (LNCS) 2826. pp.17-32, 2003. doi:10.1007/978-3-540-39920-9_3

Speaker and Poster Presentations

• Warren A Cheung, William J Rowell, Emily Farrow, Adam F Johnson, Richard Hall, Ana SA Cohen, John C Means, Tricia Zion, Daniel M Portik, Christopher T Saunders, Boryana Koseva, Chengpeng Bi, Tina Truong, Carl Schwendinger-Schreck, Byunggil Yoo, Jeffrey J Johnston, Margaret Gibson, Gilad Evrony, William B Rizzo, Isabelle Thiffault, Scott T Younger, Thomas Curran, Aaron M Wenger, Elin Grundberg, Tomi Pastinen.  Direct haplotype-resolved 5-base HiFi sequencing for genome-wide profiling of hypermethylation outliers in a rare disease cohort. Talk presented by Warren A. Cheung at the ASHG Genetics and Genomics Digital Forum (during Industry Session by PacBio: Game Changed. Redefining Genomic Sequencing with HiFi Long Reads on Revio). Nov 15-16, 2022.

• Ana S.A. Cohen, Isabelle Thiffault, Emily Farrow, Warren Cheung, Jeffrey Johnston, Tricia Zion, Lauren Bartik, Margaret Gibson, Adam Walter, Laura Puckett, Nyshele Posey, Brittany McDonald, Mary Elfrink, Suzanne Herd, Neil Miller, Tomi Pastinen. Experience using a combination of variant prioritization tools in a large rare disease cohort. Molecular Genetics and Metabolism. Volume 132, Supplement 1, April 2021, Page S26. doi:10.1016/S1096-7192(21)00484-4.  Poster at Research at Children's Mercy Month 2021, 2021 ACMG Annual Clinical Genetics Meeting.

• Warren A. Cheung, Xiaojian Shao, Tiphaine Martin, Dylan Aïssi, Emmanuelle Bouzigon, Sasha Bernantsy, Mark Lathrop, Scott Wilson, Jordana Bell, Miriam F. Moffatt, William O.C.M. Cookson, Florence Demenais, Valérie Siroux, Isabelle Pin; Brent Richards; Despoina Manousaki; Oriana Yu; Rebecca Biswell; Neil Miller; Tomi Pastinen, Elin Grundberg. Genome-wide cell-type proportion deconvolution using DNA methylation sequencing in purified and heterogeneous white blood cells . Poster presented by Warren Cheung at American Society of Human Genetics 2018. San Diego, California. Oct 16-20, 2018.

• Warren A. Cheung. Bioinformatic approaches to functional multi‐omic datasets. Oral Presentation by Warren Cheung given at the Genomic Medicine Short Course by Children's Mercy. Kansas City, Missouri.  Sept 10-13, 2018.

• Warren A. Cheung. Scaling Single Cell Genomics for Routine Comprehensive Genomic Profiling of Disease. Oral Presentation by Warren Cheung given at the Third Annual Midwest Bioinformatics Conference. Columbia, Missouri. April 11-12, 2018.

• Ashot S. Harutyunyan, Brian Krug, Simon Papillon-Cavanagh, Haifen Chen, Shriya Deshmukh, Warren A. Cheung, Rui Li, Jad Belle, Denise Bechet, Nicolas De Jay, Michele Zeinieh, Tenzin Gayden, Caterina Russo, Leonie Mikael, Damien Faury, Claudia Kleinman, Tomi Pastinen, Jacek Majewski, Nada Jabado.  Abstract B44: Identification of epigenomic changes induced by H3 K27M mutation in glioblastoma using patient-derived and CRISPR/Cas9 edited cell lines. Cancer Research 78(19 Supplement):B44-B44.  October 2018. doi: 10.1158/1538-7445.PEDCA17-B44 .  Poster presentation by Ashot Harutyunyan at Pediatric Cancer Research: From Basic Science to the Clinic. Atlanta, Georgia. Dec 3-6, 2017.

• Warren A. Cheung, Xiaojian Shao, Tiphaine Martin, Dylan Aïssi, Emmanuelle Bouzigon, Sasha Bernantsy, Mark Lathrop, Scott Wilson, Jordana Bell, Miriam F. Moffatt, William O.C.M. Cookson, Florence Demenais, Valérie Siroux, Isabelle Pin, Tomi Pastinen, Elin Grundberg. Determining Blood Cell-type Composition using DNA Methylation Sequencing. Poster presented by Warren Cheung at American Society of Human Genetics 2017. Orlando, Florida. Oct 17-21, 2017.

• Warren A. Cheung, Xiaojian Shao, Andréanne Morin, Fiona Allum, Frédéric Guénard, Valérie Siroux, Emmanuelle Bouzigon, Tony Kwan, Bing Ge, Marie-Michelle Simon, Elodie Boulier, Adriana Redensek, Lu Chen, Louella Vasquez, Stephan Watt, Avik Datta, Daniel Mead, Dirk S. Paul, Guillaume Bourque, Mark Lathrop, André Tchernof, Marie-Claude Vohl, Florence Demenais, Isabelle Pin, Hendrick G. Stunnenberg, Nicole Soranzo, Kate Downes, Elin Grundberg, Tomi Pastinen. Functional variation in allelic methylomes underscore strong genetic contribution and reveal novel epigenetic alterations in human epigenome. Poster presented by Warren Cheung at Epigenomics in Disease and Development meeting. Esterel, Quebec, Canada. Sept 18-21, 2016.

• Stephanie O.M. Dyke, Katie Saulnier, Warren Cheung, Guillaume Bourque, Tomi Pastinen and Yann Joly, On behalf of the IHEC Bioethics Workgroup. Epigenomics ELSI: The Research of the International Human Epigenome Consortium (IHEC) Bioethics Workgroup. Poster presented by Stephanie Dyke at International Congress on Personalized Health Care. Montreal, Quebec, Canada. June 12-15, 2016.

• Warren A Cheung, Tomi Pastinen. Assessing the deconvolution of genetic and epigenetic variation: technical and ethical considerations. Poster presentation given at the Keystone Symposia Conference - Epigenomics. Keystone, Colorado, USA. March 29-April 3, 2015.

• Warren A Cheung, BF Francis Ouellette and Wyeth W Wasserman. Quantitative association of authors to research topic terms using MeSHOPS. Oral presentation and poster presentation given at the Seventh International Biocuration Conference (ISB2014). Toronto, Ontario, Canada. April 6-9, 2014.

• Warren A Cheung, BF Francis Ouellette and Wyeth W Wasserman. Compensating for Literature Annotation Bias when Predicting Novel Drug-Disease Relationships through Medical Subject Heading Over-representation Profile (MeSHOP) Similarity. Oral presentation given at the Transcriptional Bioinformatics Conference 2012. Jeju Island, Korea. Oct 13th-15th, 2012.

• Warren A Cheung, BF Francis Ouellette and Wyeth W Wasserman. Inferring Novel Relationships through Over-Representation Analysis of Medical Subjects in Biomedical Bibliographies. Ph.D. Exit Seminar at the BC Cancer Research Centre. Vancouver, BC, Canada. July 6, 2012.

• Warren A. Cheung, BF Francis Ouellette, Wyeth W. Wasserman. Biomedical Topic Profiles from Bibliographical Literature Evidence. Speaker for the Vancouver Bioinformatics User Group. Vancouver, BC, Canada. February 9, 2012.

• Warren A. Cheung, BF Francis Ouellette, Wyeth W. Wasserman. Medical Subject Heading Over-representation profiles: Bibliographic Analysis of Over-represented Medical Subjects. UBC representative at Canadian Institutes for Health Research National Health Research Poster Competition, Canadian Student Health Research Forum 2011. Winnipeg, Manitoba, Canada. June 7-9, 2011. (Travel Award)

• Warren A. Cheung, BF Francis Ouellette, Wyeth W. Wasserman. Predicting Gene-Disease Relationships via Gene Characteristic Profiles Constructed from Text Analysis. Poster presented at:

  • 5th Canadian Student Conference on Biomedical Computing and Engineering. Waterloo, Ontario, Canada. May 20-22, 2010. Awarded MITACS Best Poster Award in the Area of Biomedical Science.

  • 14th International Conference on Research in Computational Molecular Biology (RECOMB 2010). Lisbon, Portugal. August 12, 2010.

  • 15th International Conference on Research in Computational Molecular Biology (RECOMB 2011). Vancouver, BC, Canada. March 29, 2011.

• W. A. Cheung. Optimising Locality-Sensitive Hashing on Sequences in the Context of Motif Finding. Oral Presentation given at the Canadian Student Conference on Biomedical Computing and Engineering (CSCBCE) 2010. Waterloo, Ontario, Canada. May 21, 2010. MITACS Best Paper Award in the Area of Bioinformatics.

• Christopher D. Fjell, Håvard Jenssen, Kai Hilpert, Warren A. Cheung, Nelly Panté, Robert E.W. Hancock and Artem Cherkasov. Optimization of antibacterial peptides by genetic algorithms and QSAR. Poster presented by Christopher Fjell at 26th International Congress of Chemotherapy and Infection. Toronto, Ontario, Canada. June 19, 2009.

• Warren A. Cheung, BF Francis Ouellette, Wyeth W. Wasserman. Indirect Gene-Disease Association via Medical Subject Term Annotation of Literature Evidence. Poster presented at:

  • Canadian Student Conference on Biomedical Computing 2009. Vancouver, BC, Canada. March 13, 2009.

  • Genome BC's 7th Annual Genomics Forum and Research Exchange Poster Competition. Vancouver, BC, Canada. April 3, 2009.

  • 2nd Human Genetics Conference. Harrison Hot Springs, BC, Canada. May 25, 2009.

  • 4th Annual Canadian Genetic Epidemiology & Statistical Genetics Meeting. Harrison Hot Springs, BC, Canada. May 28, 2009.

• Warren A. Cheung, BF Francis Ouellette, Wyeth W. Wasserman. Mining Literature Evidence for Predicting Gene-Disease Associations. Speaker for Canadian Student Conference on Biomedical Computing (CSCBC) 2008. Toronto, Ontario, Canada. March 14, 2008.

• Warren A. Cheung, BF Francis Ouellette, Wyeth W. Wasserman. Mining Literature Evidence for Predicting Gene-Disease Associations. Speaker for TGIF Seminar Series, CMMT, Vancouver, BC, Canada. February 15, 2008.

• Warren Cheung and William Evans. Pursuit-Evasion Voronoi Diagrams in L1. Oral Presentation given at the 4th International Symposium on Voronoi Diagrams in Science and Engineering (ISVD), Pontypridd, Wales, UK. July 11th, 2007.

• Warren A. Cheung, BF Francis Ouellette, Wyeth W. Wasserman. Mining Brain-Related Transcription Factor-Disease Relationships for Novel Linkages. Poster presented at the Annual Scientific Meeting of the Canadian Genetic Diseases Network (CGDN) 2007. Saint-Sauveur, Quebec, Canada. April 20-21, 2007.

• Warren A. Cheung and Ghassan Hamarneh. n-SIFT: n-Dimensional Scale Invariant Feature Transform for Matching Medical Images. Poster presented at the Fourth IEEE International Symposium on Biomedical Imaging (ISBI) 2007. Washington DC, USA. April 14, 2007.

• Warren A. Cheung and Wyeth W. Wasserman. Cis-Regulatory Elements for Purkinje Cell Specific Expression. Oral Presentation at the Vancouver Bioinformatics User Group. Vancouver, BC, Canada. January 11, 2007. VanBUG Screencast.

• Mike Klaas, Tristram Southey, and Warren Cheung. 2005. Particle-Based Communication Among Game Agents. The First Artificial Intelligence and Interactive Digital Entertainment (AIIDE) Conference. Marina del Rey, California, USA. June 1–3, 2005.

Professional Activities

Conference and Research Event Organisation

• Co-organiser, Bioinformatics & Oncology Research Day 2012, Vancouver, BC, Canada

• Co-organiser, Bioinformatics and Integrated Oncology Program Retreat 2011, Vancouver, BC, Canada.

• Co-organiser, Canadian Institute for Health Research (CIHR) Institute of Circulatory and Respiratory Health's Young Investigators Forum 2010, Vancouver, BC, Canada.

• Co-organiser, Genetics and Bioinformatics Graduate Retreat 2010, 2008, 2007, Vancouver, BC, Canada.

• Co-chair, Canadian Student Conference on Biomedical Computing 2009, Vancouver, BC, Canada.

• Co-organiser, Genetics Retreat 2006, Vancouver, BC, Canada.

Organisations

• American Society for Human Genetics. 2017-2020.

• Treasurer, BC Registered Music Teacher's Association - Student Teacher's Auxilliary (Vancouver Branch). 2000-2013.

• Founding Member/Student Representative, College for Interdisciplinary Studies Graduate Student Association, University of British Columbia. 2009-2011.

• Space Committee Computer Science Graduate Student Association Representative, Department of Computer Science, University of British Columbia. 2004-2005.

Peer-Review Article Referee

• IEEE Access, 2019

• Magnetic Resonance Materials in Physics, Biology and Medicine, 2015

• Bioinformatics, 2013

• Advances in Complex Systems, 2011

• Canadian Student Conference on Biomedical Computing and Engineering - 2009, 2010, 2011

• Database: The Journal of Biological Databases and Curation, 2010

• International Journal of Computer Assisted Radiology & Surgery, 2010

• IEEE International Conference on Robotics and Automation, 2010

• PLoS Computational Biology, 2009

• Mathematical Methods in Biomedical Image Analysis, 2008

Miscellaneous Volunteer Activities

• Volunteer Judge, 69th Greater Kansas City Science & Engineering Fair. April 2020

• Volunteer Head Judge, 68th Greater Kansas City Science & Engineering Fair. April 2019

• Volunteer Judge, Canada-Wide Science Fair/Expo-sciences Pancanadienne 2016

• Volunteer, Let's Talk Science Partnership Program - 2010-2012

  • SCIE 113 Interview Volunteer - 2010, 2011, 2012

• Volunteer, 15th International Conference on Research in Computational Molecular Biology. March 2011

• Volunteer, the International Gairdner Symposium at the Child & Family Research Institute. 2010

• Volunteer, UBC Graduate Student Society Orientation 2010

• Volunteer, Canadian Conference on Computational Geometry 2009

• Volunteer, IEEE Congress on Computational Intelligence 2006

• Volunteer, Symposium on Discrete Algorithms 2005

Other Interests

• Vintage Jazz Dance (Lindy Hop, Balboa, Blues) Instructor, Performer and Competitive Dancer

• Music Teacher (Piano, Violin, Theory)

References

• Available upon request