Search this site
Skip to main content
Skip to navigation
divya_mahapatra
Home
Research Interests
Publications
Academic Details
Ph.D. Supervisor
Teaching Assignments
Contact
divya_mahapatra
Home
Research Interests
Publications
Academic Details
Ph.D. Supervisor
Teaching Assignments
Contact
More
Home
Research Interests
Publications
Academic Details
Ph.D. Supervisor
Teaching Assignments
Contact
Publications
Utilization of methanol for condensation interrupted chemoselective transfer hydrogenation of CC, CO, and CN bonds under low catalyst loading
Selective transfer hydrogenation (TH) of unsaturated molecules using methanol is challenging as the in situ generated formaldehyde is prone to react with the active methylene (C-methylation) or amine (N-methylation) core of the desired product. In this work, an effective protocol is demonstrated for the sele
Methyl Formate, an Alternative Transfer Hydrogenating Agent for Chemoselective Reduction of N-Heteroarenes and Azoarenes
The search for efficient molecular hydrogen precursors and their catalytic exploration is necessary for the evolution of catalytic transfer hydrogenation. Methyl formate (MF) having high hydrogen content still remains unexplored for such transformations. Herein, we disclosed a bifunctional Ir(III)-complex catalyzed chemoselective TH protocol for N-heteroarenes and azoarenes using MF. A variety of substrates including ten bioactive molecules have been synthesized under mild reaction conditions. A probable mechanistic pathway was proposed based on control experiments and mechanistic studies.
Google Sites
Report abuse
Page details
Page updated
Google Sites
Report abuse