Published works related to the project

Scientific articles published on journal with I.F.

1.  Biscotti F., Bortolotti M., Falà F., Di Maro A., Bolognesi A., Polito L. (2025). Ricin Toxicity to Intestinal Cells Leads to Multiple Cell Death Pathways Mediated by Oxidative Stress. Toxins 17(8), 400. https://doi.org/10.3390/toxins17080400

2.  Bortolotti M., Biscotti F., Bolognesi A., Polito L. (2026). Antiviral Potential of Momordica charantia: From Traditional Use to Modern Implications. Biomedicines 14(2), 412. https://doi.org/10.3390/biomedicines14020412

3.  Bortolotti, M., Ragucci, S., Falà; F., Saggese, A., Biscotti, F., De Luca; Y., Landi, N., Pedone, P.V., Bolognesi; A., Ricca, E., Polito, L., Di Maro, A. (2026) Edulitin 2, a ribotoxin-like protein from Boletus edulis that triggers apoptosis in colon cancer cells while preserving the integrity of the intestinal microbiota. eFood, accepted for publication, doi: 10.1002/efd2.70138.

4.  Campanile M., Ragucci S., Di Donato I., Oliva R., Landi N., Petraccone L., Di Maro A., Del Vecchio P. (2025). Thermal stability and enzymatic activity of quinoin, a type 1 ribosome inactivating protein from quinoa seeds. Journal of Thermal Analysis and Calorimetry, https://doi.org/10.1007/s10973-025-14942-x

5.  Citores L., Ragucci S., Gay C.C., Russo R., Chambery A., Di Maro A., Iglesias R., Ferreras J.M. (2024). Edodin: A New Type of Toxin from Shiitake Mushroom (Lentinula edodes) That Inactivates Mammalian Ribosomes. Toxins 16(4):185.

6.  Hussain H.Z.F., Ragucci S., Gentile M.T., Alberico L., Landi N., Bosso A., Pizzo E., Saviano M., Pedone P.V., Citores L., Woodrow P., Di Maro A. (2025). Melleatin, an antibiofilm multitasking protein with rRNA N-glycosylase and nuclease activity from Armillaria mellea fruiting bodies. International Journal of Biological Macromolecules, 286, 138447. https://doi.org/10.1016/j.ijbiomac.2024.138447

7.  Landi N. et al. (2025). Effects of indicitin, a novel ribosome-targeting enzyme from milky mushrooms, on four human cell lines and the gut microbiota. Food & Function, 16(23), 9160–9173. https://doi.org/10.1039/d5fo03851k

8.  Novak Babič M., Ragucci S., Leonardi A., Pavšič M., Landi N., Križaj I., Gunde-Cimerman N., Sepčić K., Di Maro A. (2024). Biocontrol Potential of Sodin 5, Type 1 Ribosome-Inactivating Protein from Salsola soda L. Seeds. Biomolecules 14:336.

9.  Ragucci S., Campanile M.G., Russo V., Landi N., Hussain H.Z.F., Canonico E., Russo R., Russo M., Arcella A., Chambery A., Di Maro A. (2025). Hortensin 4, main type 1 ribosome inactivating protein from red mountain spinach seeds: Structural characterization and biological action. International Journal of Biological Macromolecules 307(Pt 2), 142085. https://doi.org/10.1016/j.ijbiomac.2025.142085

10.  Ragucci S., Russo V., Clemente A., Campanile M.G., Oliva M.A., Landi N., Pedone P.V., Arcella A., Di Maro A. (2024). Hortensins, Type 1 Ribosome-Inactivating Proteins from Seeds of Red Mountain Spinach: Isolation, Characterization, and Their Effect on Glioblastoma Cells. Toxins 16(3):135.

11.  Tiano S.M.L., Landi N., Marano V., Ragucci S., Bianco G., Cacchiarelli D., Swuec P., Silva M., De Cegli R., Sacco F., Di Maro A., Cortese M. (2024). Quinoin, type 1 ribosome inactivating protein alters SARS-CoV-2 viral replication organelle restricting viral replication and spread. International Journal of Biological Macromolecules, 280(Pt 1), 135700. https://doi.org/10.1016/j.ijbiomac.2024.135700

Congress communications

·         International Electronic Conference on Biomedicines (ECB 2025) – Oral presentation on the cytotoxic profile of sodin-5 on intestinal cell lines.

·         International Online Conference on Toxins (2025) – Presentations on ricin-induced intestinal toxicity and cytotoxic effects of edulitin 2.

·         SIB Campania Meeting (Naples, 2025) – Invited lecture on RIPs from saffron bulbs.

·         SIPMeT Congress 2024 – Evaluation of plant ribosome-inactivating protein toxicity on intestinal cells.

·         V Workshop Maria Ciaramella (CNR Naples, 2025) – Invited presentation on hortensins from red mountain spinach seeds.

·         XVII FISV Congress (Padua, 2024) – Oral communication on melleatin, a novel ribosome-inactivating protein from Armillaria mellea.

Master’s theses

·         Leone P. (2024). Evaluation of toxicity mechanisms of ribosome-inactivating proteins in intestinal cell lines.

·         Perrone C. (2025). Effects of two plant toxins on intestinal-derived cells: evaluation in in-vitro intestinal barrier models.

·         Striano M. (2024). Direct or indirect effects of protein synthesis inhibitor enzymes from edible plants and mushrooms on intestinal microorganisms. University of Naples ‘Federico II’.