2025
Nucleoporins cooperate with Polycomb silencers to promote transcriptional repression and repair at DNA double-strand breaks.
Song H and Bae Y et al. PNAS
2024
Role of CCAR family proteins in DNA damage response and cancer. Review.
Experimental Molecular Medicine
2023
OTUD5 limits replication fork instability by organizing chromatin remodelers.
de Vivo and Song et al. Nucleic Acids Research
2023
OTUD5 limits replication fork instability by organizing chromatin remodelers.
de Vivo and Song et al. Nucleic Acids Research
2022
Splicing factor SRSF3 respresses translation of p21 mRNA.
Kim J et al. Cell Death and Disease
SIAH2 regulates DNA end resection and replication fork recovery by protmoting CtIP ubiquitination.
Jeong et al. Nucleic Acids Research
RAD51 wrestles with SUMO. Author's view
Kee Y et al. Molecular and Cellular Oncology
TPORS-mediated RAD51 SUMOYlation facilitates homologous recombination repair.
Hariharasudhan et al. Nucleic Acids research
Unveiling the Chemical diversity of the deep-sea sponge Characella pachastelloides.
Afoullouss S et al. Marine Drugs
2021
Promyelocytic Leukemia Proteins regulate Fanconi Anemia gene expression.
Munkhjargal A et al. Int J Mol Sci.
2020
Transcription-replication conflicts as a a source of common fragile site instability caused by BMI1-RNF2 deficiency.
Sanchez A et al. PLOS Genetics.
2019
Bathyptilones : Terpenoids from ans Antarctic Sea Pen, Anthoptilum grandiflorum.
Thomas ASL et al. Marine Drugs.
Chronic iron exposure and c-Myc/H-ras-mediated transformation in fallopian tube cells alter the expression of EVI1, amplified at 3q26.2 in ovarian cancer.
Rockfield S et al. Oncogenesis.
Anverenes B-E, New Polyhalogenated Monoterpenes from the Antarctic Red Alga Plocamium cartilagineum. Shilling AJ S et al. Marine Drugs.
The OTUD5-UBR5 complex regulates FACT-mediated transcription at damaged chromatin.
de Vivo A et al. Nucleic Acids Research.
2016
Putting the brakes on transcription at damaged chromatin: Do Polycomb silencers do more than modify histones?
Kee Y. Molecular and Cellular Oncology.
BMI1-UBR5 axis regulates transcriptional repression at damaged chromatin.
Sanchez A et al. Proc. Natl. Acad. Sci. USA.
The USP1-UAF1 complex interacts with RAD51AP1 to promote homologous recombination repair.
Cukras S et al. Cell Cycle.
Neddylation promotes stress granule assembly.
Jayabaian AK et al. Nature Communications.
Identification of Neuregulin-2 as a novel stress granule component.
Kim JA et al. BMB Reports.
miR146a-mediated targeting of FANCM during inflammation compromises genome integrity.
Sundaravinayagam D et al. Oncotarget.
2015
Role of Deubiquitinating enzymes in DNA repair.
Kee Y* and Huang TT*. Molecular and Cellular Biology.
2014
Inactivating UBE2M impacts the DNA damage response and genome integrity involving multiple cullin ligases. Cukras S et al. PLOS One.
The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway.
Polito et al. Journal of Biological Chemistry.
2012
Molecular pathogenesis and clinical management of Fanconi anemia.
Kee Y* and D'Andrea AD*. Journal of Clinical Investigation.
Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents.
Kee Y* et al. Molecular Cancer Research.