Though extinct, Denisovans left a lasting legacy in our DNA. Through interbreeding with early modern humans, they contributed genetic material that still influences people today:
High-altitude adaptation: The EPAS1 gene variant found in Tibetans, which helps with oxygen efficiency at high elevations, likely came from Denisovans.
Immune system diversity: Denisovan DNA affects how certain immune-related genes are expressed, especially in populations like Papuans, enhancing resistance to local pathogens.
Genetic footprint: Up to 5% of Denisovan DNA is found in Melanesians and Aboriginal Australians, with smaller traces in East and Southeast Asians.
Once, we thought we knew where we came from. But then the Denisovans were found—quiet traces of a people long gone, yet still alive in us. Their discovery reminds us that we’re not just shaped by the present, but by ancient stories written in our bones. We carry their strength, their resilience, their legacy. And that means we’re never alone—we are living proof that even the smallest traces of the past can echo forward and shape greatness.