Our works
2024
Loss of GPR75 protects against non-alcoholic fatty liver disease and body fat accumulation
Mesenchymal-specific Alms1 knockout in mice recapitulates metabolic features of Alström syndrome
A brainstem to hypothalamic arcuate nucleus GABAergic circuit drives feeding
2023
Editorial: Role of estrogens as key regulators of energy homeostasis
Obesity medication lorcaserin activates brainstem GLP-1 neurons to reduce food intake and augments GLP-1 receptor agonist induced appetite suppression
2021
Pharmacological evidence for transactivation within melatonin MT2 and serotonin 5-HT2C receptor heteromers in mouse brain
2018
Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress
Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake
mTOR signaling in the arcuate nucleus of the hypothalamus mediates the anorectic action of estradiol
2017
Lorcaserin improves glycemic control via a melanocortin neurocircuit
Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
2016
Molecular mechanisms of appetite and obesity: a role for brain AMPK
Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function
Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons
2015
Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-CoA and the thermogenic effect of hypothalamic AMPK inhibition in female rats
2014
Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK
Nicotine improves obesity and hepatic steatosis and ER stress in diet-induced obese male rats
Hypothalamic mTOR: the rookie energy sensor
2012
Hyperthyroidism differentially regulates neuropeptide S system in the rat brain
Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase
2011
Hypothalamic AMP-activated protein kinase as a mediator of whole body energy balance
2010
AMP-activated protein kinase: 'a cup of tea' against cholesterol-induced neurotoxicity
"Mens sana in corpore sano": exercise and hypothalamic ER stress
Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
New insights in ghrelin orexigenic effect
Hypothalamic lipotoxicity and the metabolic syndrome
deMorentinLab
Laboratory of Neurometabolism
Contact!
University of Leeds
