Xin Electron Microscopy Group

DeepEM Lab

Transmission Electron Microscopy Deeply Reinvented


0.7 Ă… resolution electron tomography enabled by deep learning aided information recovery, Advanced Intelligent Systems, , the first ImageNet project for the TEM community is now online!

We are proud to announce DeepEM Lab is the sole contributor to 2 repositories in the GitHub's Arctic Code Vault: xinhuolin/TomoFillNet, and xinhuolin/AtomSegNet. Learn more at:

Huolin Xin is the receipient of the 2020 UCI Academic Senate Distinguished Early-Career Faculty Award for Research

Huolin Xin was granted tenure on July 1, 2020.

Huolin Xin receives Early Career Award from DOE Office of Science (link)

Our seed project Developing Natural Language Processing Tools for Mining the Rapidly Evolving COVID-19 Literature was funded. Congrats to the DeepEM team! Let's use our deep learning expertise to join the fight against the pandemic.

Our electron tomography work done in collaboration with BNL Gang Group was selected Top-10 Science and Technology Achievements of 2019 by Brookhaven National Lab (link to the tomography image)

Huolin Xin is awarded $2.5 million grant to research next-generation lithium-ion batteries (link)

4/17/2017 Anomalous metal segregation in lithium-rich material provides design rule for stable cathode in lithium-ion battery link

3/28/2017 DeconvGUI app underwent major overhaul and version 1.1 has been released

11/20/2016 Preview of a brand new Tomography in the East -- TomoIE software package is now in preview online.

10/19/2016 In-situ TEM work in press in Nature Communications

05/4/2016 Electrocatalyst work published in Nature Communications

02/25/2016 Collaborative work published in Scienceand Nature Materials

01/11/2016 Collaborative work published in Nature Energy (see press release) and Nano Energy

8/24/2015 Collaborative works published in Nature Nanotechnology, Nature Communications, Advanced Materials, and Nano Letters.

6/9/2014 Media coverage by the Sciencedaily, R&D Mag, and LBL news

6/1/2014 Media coverage by the R&D Mag, Gizmodo,, and BNL news

4/18/2014 Group member received the Distinguished Scholar Award.

Featured Publications

Professor Huolin Xin's research group at UCI has published 35 articles in Science/Nature and Nature Sister Journals. (Corresponding author on 10) (7 Science, 1 Nature, 6 Nat Materials, 11 in Nat Communications, 3 Nat Nanotechnology, 2 Nature Catalysis, 2 Nature Energy, 1 Nature Chemistry).

Metal segregation in hierarchically structured cathode materials for high-energy lithium batteries, Feng Lin, Dennis Nordlund, Yuyi Li, Matthew K. Quan, Lei Cheng, Tsu-Chien Weng, Yijin Liu*, Huolin L. Xin* & Marca M. Doeff*, Nature Energy, 1, 15004 (2016) doi:10.1038/nenergy.2015.4

Sodiation Kinetics of Metal Oxide Conversion Electrodes: a Comparative Study with Lithiation, Kai He,et al, Nano Letters, Just Accepted Manuscript, DOI: 10.1021/acs.nanolett.5b01709

Prescribed nanoparticle cluster architectures and low-dimensional arrays built using octahedral DNA origami frames, Nature Nanotechnology, (2015) doi:10.1038/nnano.2015.105

Revealing the Atomic Restructuring of Pt-Co Nanoparticles, H. L. Xin et al, Nano Letters, DOI: 10.1021/nl500553a (link)

Is There a Stobbs Factor in Atomic-Resolution STEM-EELS Mapping?, H L Xin*, C Dwyer, DA Muller, Utramicroscopy,

DOI: 10.1016/j.ultramic.2014.01.006

Scanning Confocal Electron Energy-Loss Microscopy Using Valence-Loss Signals, H. L. Xin et al, Microscopy and Microanalysis, FirstView, doi:

Structurally Ordered Intermetallic Platinum-Cobalt Core-Shell Nanoparticles with Enhanced Activity and Stability as Oxygen Reduction Electrocatalysts, D. Wang*, H. L. Xin* (*equal contribution) et al,Nat. Mater., 12, 81 (2012)

Determining On-Axis Crystal Thickness with Quantitative Position-Averaged Incoherent Bright-Field Signal in an Aberration-corrected STEM

Huolin L. Xin, Ye Zhu and David A. Muller, Microscopy and Microanalysis, in press (preprint)

Pt-Decorated PdCo@Pd/C Core-Shell Nanoparticles with Enhanced Stability and Electrocatalytic Activity for Oxygen Reduction Reaction

D. Wang, H. L. Xin et al

J. Am. Chem. Soc., 2010, Article ASAP, DOI: 10.1021/ja107874u (preprint)