Programma Scientifico

Invited Speakers 

Programma Scientifico 

Mercoledì, 27 settembre 2023

12:30 - 14:20         Registrazione dei partecipanti

14:20 - 14:30        Cerimonia di apertura (Michael Assfalg – Francesco Peri)

Chairpersons:    Cristina Airoldi, Alessandro Palmioli

14:30 - 15:15          IL01 Luisa De Cola

Hybrid nanomaterials for imaging targeting and killing tumors

15:15 - 15:30          OR01 Alessandra Romanelli

Self-assembly of PNA conjugated to aromatic peptides into fibers

15:30 - 15:45         OR02 Concetta Di Natale

Polymeric Engineered Microneedles for Triple breast cancer treatment

15:45 - 16:00        OR03 Matteo Di Giosia

Proteins as Trojan Horse for biomedical applications of fullerenes

16:00 - 16.15         OR04 Alessia Distefano

From Amino Acid Recognition to Insulin Aggregation Monitoring: Unveiling the Versatile Potential of Carbon Dots' Fluorescence Properties

16:15 - 16:55 Coffee break & Poster Session

Chairpersons:   Gianluca Caprini, Michael Assfalg

16:55 - 17:00         Cerimonia di consegna del Premio Italfarmaco “G. De Santis”

17:00 - 17:30        AL01 Cecilia Pozzi

Structural evidence of the dimerization of C-type lectin-like receptor CD93, promoting its binding to Multimerin-2 in endothelial cells

17:30 - 19:00        Assemblea dei Soci della Divisione di Chimica dei Sistemi Biologici  

Giovedì, 28 settembre 2022

Chairpersons:   Alessandra Magistrato, Laura Legnani

09:00 - 09:45      IL02 Giorgio Colombo

The dynamics of molecular design

09:45 - 10:00       OR05 Francesco Rinaldi

Elucidating the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics

10:00 - 10:15         OR06 Alessio Bartocci

A millisecond coarse-grained simulation approach to decipher allosteric cannabinoid binding at the glycine receptor α1

10:15 - 10:30         OR07 Roberta Listro

Targeting the HuR–RNA complex: an opportunity for discovering anticancer agents

10:30 - 11:30          Coffee break & Poster Session

Chairpersons:   Stefano Mangani, Jussara Amato

11:30 - 11:45           OR08 Giulia Antonini

Developing glycomimetic inhibitors for the N-terminal domain of the bacterial lectin BC2L-C through covalent strategies

11:45 - 12:00         OR09 Angela Parise

Elucidating the intricate regulatory mechanisms of Rac1 cancer isoforms through all-atom simulations

12.00 - 12.15          OR10 Valentina Oliveri

New copper-based strategies to combat cancer

12:15 - 12:30          OR11 Roberto Paciotti

An insight of early PrP‐E200K aggregation by the combined FMO/GRID approach

12:30 - 12:45         OR12 Daniele Trivellato

Site-specific double monoubiquitination of the Alzheimer’s related tau protein impairs self-assembly and coacervation

12:45 - 13:00         OR13 Michele Francesco Maria Sciacca

Amyloid β 8-20 fragment as a promising disease-modifying drug candidate for Alzheimer’s disease treatment

13:00 - 14:30        Pranzo

Chairpersons:   Francesco Peri, Roberta Pierattelli

14:30 - 15:15          IL03 Mariagrazia Pizza

The journey of the MenB vaccine, from the discovery to real world impact

15:15 - 15:30          OR14 Matteo Calvaresi

Refactored Bacteriophages: Engineered Viral Vectors for Receptor Targeted Photodynamic/Sonodynamic Therapy

15:30 - 15:45         OR15 Concetta Avitabile

miRNA-486-5p detection in Serum for Non-Invasive Coeliac Disease Diagnosis

15:45 - 16:00        OR16 Mohammed Monsoor Shaik

Integrating Biology and Medicinal Chemistry: Advancing Therapeutic Interventions through Toll-like Receptor 4 (TLR4) Modulators

16:00 - 16:45        Coffee break & Poster Session

Chairperson:      Jussara Amato, Danilo Milardi

16:45 - 17:00        OR17 Andrea Trabocchi

Peptidomimetics targeting protein-protein interactions: disruption of SARS-CoV-2 Spike:hACE2 interaction as a case study towards the development of viral entry inhibitors

17:00 - 17:15          OR18 Tessa Bolognesi

Expression of Nucleocapsid protein (N) from SARS-CoV 2 and its characterization through high-field NMR spectroscopy

17:15 - 17:30          OR19 Alessia De Santis

PROTAC-based approach to develop broad-spectrum antiviral agents triggering the proteolysis of the major viral protease

17:30                      Tempo libero per la visita della città

20:00                    Cena Sociale presso “IL TRENO SALA LIBERTY” Via San Gregorio, 46 Milano

Venerdi, 29 Settembre 2023

Chairpersons:   Massimiliano Coletta, Danilo Milardi

09:00 - 09:05      Cerimonia di consegna della Medaglia “G. Barone”

09:05 - 09:50      AL2 Giulietta Smulevich

Structural and functional properties of heme proteins as revealed by resonance Raman spectroscopy

09:50 - 10:05       OR20 Katiuscia Pagano

Inhibition of FGFR signaling by targeting FGF/FGFR extracellular interactions: NMR approaches for the comprehension of the molecular mechanism

10.05 - 10.20        OR21 Carlotta Ciaramelli

NMR-based metabolomic analysis of Antarctic soils: a pilot study

10:20 - 10:35         OR22 Gabriele Giachin

Acyl-CoA dehydrogenase 9 (ACAD9) is a new mitochondrial Complex I (CI) interactor: structural characterization of the CI-ACAD9 assembly and targeted-NMR metabolomics on the ACAD9 substrate palmitoyl-CoA

10:35 - 11:30          Coffee break & Poster Session

Chairpersons:   Gaetano Malgieri, Alessandra Magistrato

11:30 - 11:45           OR23 Marta De Zotti

Synthesis and structure-activity relationship of medium-length peptaibols

11:45 - 12:00         OR24 Riccardo Bonsignore

Non-conventional Co(III) Schiff Base complexes as DNA binders

12:00 - 12:15          OR25 Nicola Grasso

Synthesis and characterization of a G-quadruplex-binding peptide

12:15 - 12:30          OR26 Clelia Giannini

Cyclic triimidazole derivatives as novel G-Quadruplex DNA stabilizers

12:30 - 12:45         OR27 Raffaele Graziano

Identification and targeting of G-quadruplex structures in a long non-coding RNA involved in multiple myeloma

12:45 - 13:00         OR28 Alessio Terenzi

Multimeric G-quadruplex structures as promising targets for anticancer metal-based compounds

13:00 - 13:15          Conclusione dei lavori e saluti finali