Development of SERS enabled lab on chip biosensor device based on 2D (bimetal, bilayer, etc) and 3D plasmonic nanostructures. 2D SERS substrates are fabricated from metal (Ag, Au and Cu) and bi-metal (Ag-Cu, Ag-Au, Bi-Ag, Bi-In, Bi-Cu, etc) nanostructures whereas 3D substrates are from metal-semiconductor (Ag-ZnO, AgCu-ZnO, etc.) hybrid structures. 45 fold enhancements is observed from 3D in comparison with 2D for the first time. The detection limit, repeatability and reusability tests carried out on as prepared SERS substrates using Glucose, DNA and Hemoglobin molecules.
Homogeneity test from Ag-Cu bimetal SERS substrate
References:
P Nandhagopal, NB Shinde, ES Kumar, DB Mohan, Probing the interfacial interactions of N719 with MoS2 using intrinsic surface enhanced Raman scattering, Applied Surface Science 604 (2022) 154581.
Anil Kumar Pal, Goutam Kumar Chandra, Siva Umapathy, D. Bharathi MohanUltra-sensitive, reusable and superhydrophobic Ag/ZnO/Ag 3D hybrid SERS substrate for hemoglobin detection, Journal of Applied Physics, 127 (2020) Issue 17, 164501. (IF: 2.546)
Anil Kumar Pal, Sudhakar Pagal, Kenchappa Prashanth, Goutam Kumar Chandra, Siva Umapathy, D. Bharathi Mohan, Ag/ZnO/Au 3D hybrid nanostructured reusable SERS substrate as highly sensitive platform for DNA detection, Sensors and Actuators B: Chemical, 279 (2019) 157-169. (IF:6.393).
Anil Kumar Pal and D. Bharathi Mohan,SERS enhancement, sensitivity and homogeneity studies on bi-metallic Ag-Cu films through tuning of broad band SPR towards red region, JOURNAL OF ALLOYS AND COMPOUNDS,698 (2017) 460-468.
Anil Kumar Pal and D. Bharathi Mohan,Structural, morphological and optical properties of Ag-AgO thin films with the effect of increasing film thickness and annealing temperature, OPTICAL MATERIALS, 48 (2015) 121-132.
Anil Kumar Pal and D. Bharathi Mohan, Fabrication of partially oxidized ultra-thin nanocrystalline silver films: effect of surface plasmon resonance on fluorescence quenching and surface enhanced Raman scattering, MATERIALS RESEARCH EXPRESS (IOP Publisher), 1 (2014) 025014.