WELCOME!
The Dahms research group consists of super talented undergraduate, graduate and postdoctoral researchers. Each student endeavors to carve out an original research question that can be addressed using both traditional biochemical, microbiological and advanced microscopic methods.
Dahms had begun her tenure at the UofR studying lipid-lipid and protein-lipid interactions, until, she claims, the microbes ate her lab. Her collaborative efforts with mycologists, microbiologists and even botanists shifted the direction of her research. This led to establishing novel methods, based on atomic force microscopy (AFM) for assessing microbial cell wall integrity and architecture (Snook, Ma, Paul, Jun). These methods were applied to determining the unintended impact of the common herbicide, 2,4-D, on soil microbes (Bhat), with obvious environmental implications. This research was used to develop a proof of principle novel correlative (AFM-confocal) microscopy assay for assessing xenobiotic stressor impact on live bacterial, yeast and human cells (Bhat, Shahina, Sultana).
Dahms’ AFM-based, fundamental mycological research was expanded to examine the mechanistic impact of plant-based essential oils as antifungals (Shahina, Sultana), with clinical applications. That work is being continued to determine how monoterpenoid essential oil components may serve as synergistic partners with traditional antifungals (Acuna, Price, Molaeitarabi, Patel). Recent discoveries include the link between fungal-human cell interactions and cancer (Ndlovu, Beck-McKenzie).