Using human pluripotent stem cell (hiPSC) derived cardiovascular cells can faithfully recapitulate key functional properties of cardiac and cardiovascular system in vivo. This project will develop new technologies with microfabricated tissue gauges and magnetic sensor systems that can give a realtime readout of the kinetic response.

Cardiovascular diseases (CVDs) accounted for 31% of all deaths globally. Inherited cardiac disease (i.e. arrhythmogenic right ventricular dysplasia/cardiomyopathy and vascular Ehlers-Danlos Syndrome), are affected by mechanical stress and cause early death.