Contributions to Journal Cover Pages

 Selected Journal Publications

• Iyer DR, Venkatraman J, Tanguy E, Vitale N, Mahapatra NR. 2023. Chromogranin A and its derived peptides: potential regulators of cholesterol homeostasis. Cell Mol Life Sci. 80:271. DOI: 10.1007/s00018-023-04908-3

• Illath K, Kar S, Shinde A, Ojha R, Iyer DR, Mahapatra NR, Nagai M, Santra TS. 2023. Microfluidic device-fabricated spiky nano-burflower shape gold nanomaterials facilitate large biomolecule delivery into cells using infrared light pulses. Lab Chip. 23:4783-4803. DOI: 10.1039/d3lc00341h 

• Gupta N, Kumar A, Vaddavalli PK, Mahapatra NR, Varshney A, Ghosh P. 2023. Efficient reduction of the scrolling of Descemet membrane endothelial keratoplasty grafts by engineering the medium. Acta Biomater. 171:239-248. DOI: 10.1016/j.actbio.2023.09.024

• Dhat R, Mongad D, Raji S, Arkat S, Mahapatra NR, Singhal N, Sitasawad SL. 2023. Epigenetic modifier alpha-ketoglutarate modulates aberrant gene body methylation and hydroxymethylation marks in diabetic heart. Epigenetics Chromatin. 16:12. DOI: 10.1186/s13072-023-00489-4

• Shinde A, Shinde P, Kar S, Illath K, Dey S, Mahapatra NR, Nagai M, Santra TS. 2023. Metallic micro-ring device for highly efficient large cargo delivery in mammalian cells using infrared light pulses. Lab Chip. 23:2175-2192. DOI:10.1039/d2lc00899h 

• Iyer DR, Arige V, Ananthamohan K, Sundaramurthy V, Tokinoya K, Aoki K, Kurtz CL, Sethupathy P, Takekoshi K and Mahapatra NR. 2023. Cyclic-AMP response element binding protein (CREB) and microRNA miR-29b regulate renalase gene expression under catecholamine excess conditions. Life Sci. 328:121859. DOI:10.1016/j.lfs.2023.121859 

• Steenblock C, Toepfner N, Beuschlein F, Perakakis N, Mohan Anjana R, Mohan V, Mahapatra NR, Bornstein SR. 2023. SARS-CoV-2 infection and its effects on the endocrine system. Best Pract Res Clin Endocrinol Metab. 5:101761. DOI: 10.1016/j.beem.2023.101761

• Arkat S, Poovitha S, Vijayakumar A, Dhat R, Sitasawad SL and Mahapatra NR. 2023. Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-κB. Biochim. Biophys. Acta - Mol. Basis Dis. 1869:16691. DOI:10.1016/j.bbadis.2023.166691 

• Kumar A, Rajamanickam R, Hazra J, Mahapatra NR and Ghosh P. 2022. Engineering the nonmorphing point of actuation for controlled drug release by hydrogel bilayer across the pH spectrum. ACS Appl Mater Interfaces 14(50):56321–56330. DOI:10.1021/acsami.2c16658 

• Maghajothi S, Subramanian L, Mani P, Singh M, Iyer DR, Sharma S, Khullar M, Victor SM, Asthana S, Mullasari AS and Mahapatra NR. 2022. A common Matrix metalloproteinase 8 promoter haplotype enhances the risk for hypertension via diminished interactions with nuclear factor kappa B. J Hypertens 40:2147-2160. DOI:10.1097/HJH.0000000000003234 

• Vijayakumar A and Mahapatra NR. 2022. Renalase: a novel regulator of cardiometabolic and renal diseases. Hypertens Res 45:1582-1598. DOI:10.1038/s41440-022-00986-1 

• Khan AA, Gupta V, Mahapatra NR. 2022. Key regulatory miRNAs in lipid homeostasis: Implications for cardiometabolic diseases and development of novel therapeutics. Drug Discov Today 27:2170-2180. DOI:10.1016/j.drudis.2022.05.003 

• Allu PK, Kiranmayi M, Mukherjee SD, Chirasani VR, Garg R, Vishnuprabu D, Ravi S, Subramanian L, Sahu BS, Iyer DR, Maghajothi S, Sharma S, Ravi MS, Khullar M, Munirajan AK, Gayen JR, Senapati S, Mullasari AS, Mohan V, Radha V, Naga Prasad SV, Mahapatra NR. 2022. Functional Gly297Ser Variant of the Physiological Dysglycemic Peptide Pancreastatin Is a Novel Risk Factor for Cardiometabolic Disorders. Diabetes 71:538–553. DOI:10.2337/db21-0289  (Cover page article)

• Khan AA, Sundar P, Natarajan B, Gupta V, Arige V, Reddy SS, Barthwal MK, Mahapatra NR. 2021.  An evolutionarily-conserved promoter allele governs HMG-CoA reductase expression in spontaneously hypertensive rat. J Mol Cell Cardiol  158:140-152. DOI:10.1016/j.yjmcc.2021.05.017  (Cover page article)

• ​Natarajan B, Arige V,  Khan AA, Reddy SS, Barthwal MK, Mahapatra NR. 2021. Hypoxia-mediated regulation of mitochondrial transcription factors in renal epithelial cells: implications for hypertensive renal physiology. Hypertens Res 44:154-167. DOI:10.1038/s41440-020-00539-4 

• ​Khan AA, Agarwal H, Reddy SS, Arige V, Natarajan B, Gupta V, Kalyani A, Barthwal MK, Mahapatra NR. 2020. MicroRNA-27a is a key modulator of cholesterol biosynthesis. Mol Cell Biol 40:e00470-19. DOI:10.1128/mcb.00470-19 

• Alam MJ, Gupta R, Mahapatra NR, Goswami SK. 2020. Catestatin reverses the hypertrophic effects of norepinephrine in H9c2 cardiac myoblasts by modulating the adrenergic signaling. Mol Cell Biochem 464:205-219. DOI:10.1007/s11010-019-03661-1 

• Subramanian L, Maghajothi S, Singh M, Kesh K, Kalyani A, Sharma S, Khullar M, Victor SM, Swarnakar S, Asthana S, Mullasari AS, Mahapatra NR. 2019. A Common Tag Nucleotide Variant in MMP7 Promoter Increases Risk for Hypertension via Enhanced Interactions With CREB (Cyclic AMP Response Element-Binding Protein) Transcription Factor. Hypertension 74:1448-1459. DOI:10.1161/HYPERTENSIONAHA.119.12960 

• Arige V, Agarwal A, Khan AA, Kalyani A, Natarajan B, Gupta V, Reddy SS, Barthwal MK, Mahapatra NR. 2019. Regulation of Monoamine Oxidase B Gene Expression: Key Roles for Transcription Factors Sp1, Egr1 and CREB, and microRNAs miR-300 and miR-1224. J Mol Biol 431:1127-1147. DOI:10.1016/j.jmb.2019.01.042 

• Mahata SK, Kiranmayi M, Mahapatra NR. 2018. Catestatin: A master regulator of cardiovascular functions. Curr Med Chem 25:1352-1374. DOI:10.2174/0929867324666170425100416 

• Subramanian L, Khan AA, Allu PKR, Kiranmayi M, Sahu BS, Sharma S, Khullar M, Mullasari AS, Mahapatra NR. 2017. A haplotype variant of the human chromogranin A gene (CHGA) promoter increases CHGA expression and the risk for cardiometabolic disorders. J Biol Chem  292:13970-13985. DOI:10.1074/jbc.m117.778134 

• Wollam J, Mahata S, Riopel M, Hernandez-Carretero A, Biswas A, Bandyopadhyay GK, Chi NW, Eiden LE, Mahapatra NR, Corti A, Webster NJG, Mahata SK. 2017. Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion. Cell Tissue Res 368:487-501. DOI:10.1007/s00441-017-2580-5 

• Gupta V, Kapopara PR, Khan AA, Arige V, Subramanian L, Sonawane PJ, Sasi BK, Mahapatra NR. 2017. Functional promoter polymorphisms direct the expression of cystathionine gamma-lyase gene in mouse models of essential hypertension. J Mol Cell Cardiol 102: 61-73. DOI:10.1016/j.yjmcc.2016.11.005  (Cover page article)

• Kiranmayi M, Chirasani VR, Allu PK, Subramanian L, Martelli EE, Sahu BS, Vishnuprabu D, Kumaragurubaran R, Sharma S, Bodhini D, Dixit M, Munirajan AK, Khullar M, Radha V, Mohan V, Mullasari AS, Naga Prasad SV, Senapati S, Mahapatra NR. 2016. Catestatin Gly364Ser variant alters systemic blood pressure and the risk for hypertension in human populations via endothelial nitric oxide pathway. Hypertension 68:334-347. DOI:10.1161/HYPERTENSIONAHA.116.06568  

• Kalyani A, Sonawane PJ, Khan AA, Subramanian L, Ehret GB, Mullasari AS, Mahapatra NR. 2015.  Post-transcriptional Regulation of Renalase Gene by miR-29 and miR-146 MicroRNAs: Implications for Cardio-metabolic Disorders. J Mol Biol 427: 2629–2646. DOI:10.1016/j.jmb.2015.07.003 

• Gupta V, Khan AA, Sasi BK, Mahapatra NR. 2015. Molecular mechanism of monoamine oxidase A gene regulation under inflammation and ischemia-like conditions: key roles for the transcription factors GATA2, Sp1 and TBP. J Neurochem 134:21-38. DOI:10.1111/jnc.13099 

• Kesh K, Subramanian L, Ghosh N, Gupta V, Gupta A, Bhattacharya S, Mahapatra NR, Swarnakar 2015. Association of MMP7−181A/G promoter polymorphism with gastric cancer risk: Influence of nicotine in differential allele-specific transcription via increased phosphorylation of CREB. J Biol Chem 290:14391-14406. DOI:10.1074/jbc.m114.630129 

• Sonawane PJ, Gupta V, Sasi BK, Kalyani A, Natarajan B, Khan AA, Sahu BS, Mahapatra NR. 2014. Transcriptional Regulation of the Novel Monoamine Oxidase Renalase: Crucial Roles of Transcription Factors Sp1, STAT3 and ZBP89. Biochemistry 53: 6878-6892. DOI:10.1021/bi500798n 

• Allu PK, Chirasani VR, Ghosh D, Mani A, Bera AK, Maji SK, Senapati S, Mullasari AS, Mahapatra NR. 2014. Naturally occurring variants of the dysglycemic peptide pancreastatin: differential potencies for multiple cellular functions and structure-function correlation. J Biol Chem 289: 4455–4469. DOI:10.1074/jbc.M113.520916 

• Sasi BK, Sonawane PJ, Gupta V, Sahu BS, Mahapatra NR. 2014.Coordinated transcriptional regulation of Hspa1a gene by multiple transcription factors: crucial roles for HSF-1, NF-Y, NF-κB and CREB. J Mol Biol 426:116-35. DOI:10.1016/j.jmb.2013.09.008 

• Friese RS, Altshuler AE, Zhang K, Miramontes-Gonzalez JP, Hightower CM, Jirout ML, Salem RM, Gayen JR, Mahapatra NR, Biswas N, Cale M, Vaingankar SM, Kim HS, Courel M, Taupenot L, Ziegler MG, Schork NJ, Pravenec M, Mahata SK, Schmid-Schönbein GW, O’Connor DT. 2013. MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension. Hum Mol Genet 22: 3624-3640. DOI:10.1681/ASN.2014060537 

• Sahu BS, Mohan J, Sahu G, Allu PKR, Subramanian L, Sonawane PJ, Singh PK, Sasi BK, Senapati S, Maji SK, Bera AK, Gomathi BS, Mullasari AS, Mahapatra NR. 2012. Functional genetic variants of the catecholamine-release-inhibitory peptide catestatin in an Indian population: allele-specific effects on metabolic traits. J Biol Chem 287: 43840-43852. DOI:10.1074/jbc.m112.407916 

• ​Sahu BS, Mohan J, Sahu G, Singh PK, Sonawane PJ, Sasi BK, Allu PKR, Maji SK, Bera AK, Senapati S, Mahapatra NR. 2012. Molecular interactions of the physiological anti-hypertensive peptide catestatin with the neuronal nicotinic acetylcholine receptor. J Cell Sci 125: 2323–2337. DOI:10.1242/jcs.103176

• Friese RS, Ye C, Nievergelt CM, Schork AJ, Mahapatra NR, Rao F, Napolitan PS, Waalen J, Schmid-Schönbein GW, Eskin E, O’Connor DT. 2012. Integrated computational and experimental analysis of the neuroendocrine transcriptome in genetic hypertension identifies novel control points for the cardio-metabolic syndrome. Circ Cardiovasc Genet 5:430-440. DOI:10.1161/CIRCGENETICS.111.962415

• Mahata M, Zhang K, Gayen JR, Nandi S, Brar BK, Ghosh S, Mahapatra NR, Taupenot L, O’Connor DT, Mahata SK. 2011. Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin. Cell Tissue Res 345:87-102. DOI:10.1007/s00441-011-1177-7 

• Sonawane PJ, Sahu BS, Sasi BK, Geedi P, Lenka G, Mahapatra NR. 2011. Functional promoter polymorphisms govern differential expression of HMG-CoA reductase gene in mouse models of essential hypertension. PLoS ONE 6: e16661 (1-16).​​ DOI:10.1371/journal.pone.0016661 

• Jirout ML, Friese RS, Mahapatra NR, Mahata M, Taupenot L, Mahata SK, Křen V, Zídek V, Fischer J, Maatz H, Ziegler MG, Pravenec M, Hubner N, Aitman TJ, Schork NJ, O’Connor DT. 2010. Genetic regulation of catecholamine synthesis, storage and secretion in the spontaneously hypertensive rat. Hum Mol Genet 19: 2567-2580. DOI:10.1093/hmg/ddq135 

• Sahu BS, Sonawane PJ, Mahapatra NR. 2010. Chromogranin A: a novel susceptibility gene for essential hypertension. Cell Mol Life Sci 67:861-874. DOI:10.1007/s00018-009-0208-y 

• Friese RS, Gayen JR, Mahapatra NR, Schmid-Schonbein G, O’Connor DT, Mahata SK. 2010. Global metabolic consequences of a monogenic model of hypertension: Transcriptomic detection, pathway identification, and experimental verification of dissociated features of the metabolic syndrome. Physiol Genomics 40:195-207. DOI:10.1152/physiolgenomics.00164.2009 

• Mahapatra NR. 2008. Catestatin is a novel endogenous peptide that regulates cardiac function and blood pressure. Cardiovasc Res 80:330-338.​ DOI:10.1093/cvr/cvn155 

Selected Book Chapters

• Hazra J, Vijayakumar A, Mahapatra NR. 2023. Emerging Role of Heat Shock Proteins in Cardiovascular Diseases. In: Advances of Protein Chemistry and Structural Biology, 134, pp. 271-306. Academic Press Inc., United States. DOI:10.1016/bs.apcsb.2022.10.008 

• Gupta V, Arige V, Mahapatra NR. 2019. Role of Monoamine Oxidases in Heart Diseases. In: Modulation of Oxidative Stress in Heart Disease, pp. 129-150. Springer, Singapore. DOI:10.1007/978-981-13-8946-7_6 ​

• Mahapatra NR, Ghosh S, Mahata M, Bandyopadhyay GK, Mahata SK. 2017. Naturally Occurring Single Nucleotide Polymorphisms in Human Chromogranin A (CHGA) Gene: Association with Hypertension and Associated Diseases. In:Chromogranins: from Cell Biology to Physiology and Biomedicine (Angelone T, Cerra M & Tota B; Eds). pp. 195-211. Springer International Publishing AG, Cham, Switzerland. DOI:10.1007/978-3-319-58338-9_12                                                

• Sonawane PJ, Sahu BS, Mahapatra NR. 2011. Pharmacogenomics of Cardiovascular Drugs. In: Drug Design-Basics and Applications (Doble M, Ed.). pp. 280-310. Tata-McGraw-Hill Publishers, New Delhi, India.