CARDIOVASCULAR GENETICS LAB
INDIAN INSTITUTE OF TECHNOLOGY MADRAS
Media Coverage
Media Coverage/Popular Articles
Research Article: Maghajothi S, Subramanian L, Mani P, Singh M, Iyer DR, Sharma S, Khullar M, Victor SM, Asthana S, Mullasari AS and Mahapatra NR. 2022. A common Matrix metalloproteinase 8 promoter haplotype enhances the risk for hypertension via diminished interactions with nuclear factor kappa B. J Hypertens 40:2147-2160.
Featured in the following news coverage:
Research Article: Vijayakumar A and Mahapatra NR. 2022. Renalase: a novel regulator of cardiometabolic and renal diseases. Hypertens Res 45:1582-1598.
Featured in IITM Tech-Talk:
https://tech-talk.iitm.ac.in/renalase-a-multifunctional-protein/
Research Article: Allu PK, Kiranmayi M, Mukherjee SD, Chirasani VR, Garg R, Vishnuprabu D, Ravi S, Subramanian L, Sahu BS, Iyer DR, Maghajothi S, Sharma S, Ravi MS, Khullar M, Munirajan AK, Gayen JR, Senapati S, Mullasari AS, Mohan V, Radha V, Naga Prasad SV, Mahapatra NR. 2022. Functional Gly297Ser Variant of the Physiological Dysglycemic Peptide Pancreastatin Is a Novel Risk Factor for Cardiometabolic Disorders. Diabetes 71: 538–553.
Featured extensively in news media including:
https://www.youtube.com/watch?v=MBe8E0bqZZw
Research Article: Khan AA, Sundar P, Natarajan B, Gupta V, Arige V, Reddy SS, Barthwal MK, Mahapatra NR. 2021. An evolutionarily-conserved promoter allele governs HMG-CoA reductase expression in spontaneously hypertensive rat. J Mol Cell Cardiol 158:140-152.
Featured in the following news coverage:
https://www.thehindubusinessline.com/business-tech/flip-the-bp-switch/article35923946.ece
News Article: Battling high blood pressure in the COVID-19 era
https://covid-gyan.in/article/battling-high-blood-pressure-covid-19-era?
Research Article: Subramanian L, Maghajothi S, Singh M, Kesh K, Kalyani A, Sharma S, Khullar M, Victor SM, Swarnakar S, Asthana S, Mullasari AS, Mahapatra NR. 2019. A Common Tag Nucleotide Variant in MMP7 Promoter Increases Risk for Hypertension via Enhanced Interactions With CREB (Cyclic AMP Response Element-Binding Protein) Transcription Factor. Hypertension 74:1448-1459.
Featured in numerous news media including:
https://timesofindia.indiatimes.com/city/chennai/study-finds-gene-that-triggers-hypertension/articleshow/72960922.cms;
https://www.thehindubusinessline.com/news/science/iit-madras-researchers-find-link-between-a-tissue-remodelling-enzyme-and-hypertension-risk/article30388648.ece;
https://educationtimes.com/article/campus-beat-college-events/72955058/IIT-Madras-collaborates-to-find-link-between-a-tissue-remodelling-enzyme-and-risk-of-Hypertension;
https://www.outlookindia.com/newsscroll/iitm-finds-link-between-tissueremodelling-enzyme-hypertension/1693108; http://www.ianslive.in/index.php?param=news/IIT_M_finds_link_between_tissue_remodelling_enzyme_hypertension-649927/SCI-TECH%20and%20HEALTH/36;
https://www.indiatoday.in/education-today/news/story/iit-madras-researchers-find-link-between-a-tissue-remodelling-enzyme-and-risk-of-hypertension-1631131-2019-12-24;
https://www.gadgetsnow.com/tech-news/iit-m-finds-link-between-tissue-remodelling-enzyme-hypertension/articleshow/72953744.cms;
https://indiaeducationdiary.in/iit-madras-researchers-find-link-between-a-tissue-remodelling-enzyme-and-risk-of-hypertension/;
https://health.economictimes.indiatimes.com/news/diagnostics/iit-m-finds-link-between-tissue-remodelling-enzyme-hypertension/72952881;
https://www.timesnownews.com/education/article/iit-madras-finds-link-between-tissue-remodelling-enzyme-hypertension/531255;
https://navbharattimes.indiatimes.com/lifestyle/health/iit-madras-team-finds-new-gene-that-triggers-hypertension-among-indians/articleshow/72974484.cms;
https://www.daijiworld.com/news/newsDisplay.aspx?newsID=656587;
http://www.canindia.com/iit-m-finds-link-between-tissue-remodelling-enzyme-hypertension/;
http://www.uniindia.com/~/iit-m-researchers-find-link-between-tissue-remodelling-enzyme-and-risk-of-hypertension/States/news/1832099.html;
https://www.ibtimes.co.in/iit-m-finds-link-between-tissue-remodelling-enzyme-hypertension-810742; http://www.theweekendleader.com/Headlines/46700/iit-m-finds-link-between-tissue-remodelling-enzyme-hypertension-.html;
https://www.socialnews.xyz/2019/12/24/iit-m-finds-link-between-tissue-remodelling-enzyme-hypertension/;
https://newsd.in/iit-m-finds-link-between-tissue-remodelling-enzyme-hypertension/;
https://www.newkerala.com/news/read/268882/iit-m-finds-link-between-tissue-remodelling-enzyme-hypertension.html; https://speciality.medicaldialogues.in/iit-madras-study-links-tissue-remodelling-enzyme-to-increased-hypertension-risk/; https://heraldpublicist.com/iit-m-finds-link-between-tissue-remodelling-enzyme-hypertension/;
https://headlinezpro.com/iit-m-finds-link-between-tissue-remodelling-enzyme-hypertension/; https://www.biospectrumindia.com/news/58/15414/iit-m-researchers-conduct-study-on-risk-of-hypertension.html)
Research Article: Subramanian L, Khan AA, Allu PKR, Kiranmayi M, Sahu BS, Sharma S, Khullar M, Mullasari AS, Mahapatra NR. 2017. A haplotype variant of the human chromogranin A gene (CHGA) promoter increases CHGA expression and the risk for cardiometabolic disorders. J Biol Chem 292:13970-13985.
Featured in the following news media:
http://www.thehindu.com/sci-tech/health/blame-it-on-the-genes/article19778751.ece
http:// vigyanprasar.gov.in/isw/heartdisease.html
https://scroll.in/pulse/852266/lab-notes-scientists-identify-a-gene-that-puts-indians-at-higher-risk-of-heart-disease
http://www.apnlive.com/science/study-identifies-genetic-link-to-heart-disease-in-indian-population-28428
http://www.downtoearth.org.in/news/carrying-set-of-genes-puts-you-on-higher-risk-of-cardiovascular-diseases-study-58765
http://www.biovoicenews.com/study-identifies-genetic-link-heart-disease-indian-population
http://netindian.in/news/2017/09/29/00043430/study-identifies-genetic-link-heart-disease-indian-population
Research Article: Sahu BS, Obbineni JM, Sahu G, Allu PKR, Subramanian L, Sonawane PJ, Singh PK, Sasi BK, Senapati S, Maji SK, Bera AK, Gomathi BS, Mullasari AS, Mahapatra NR. 2012. Functional genetic variants of the catecholamine-release-inhibitory peptide catestatin in an Indian population: allele-specific effects on metabolic traits. J Biol Chem 287: 43840-43852
Featured in Nature India:
https://www.natureasia.com/en/nindia/article/10.1038/nindia.2012.177
Research Article: Abdul Khaliq R, Sonawane PJ, Sasi BK, Sahu BS, Pradeep T, Das SK, Mahapatra NR. 2010. Enhancement in the efficiency of polymerase chain reaction by TiO2 nanoparticles: crucial role of enhanced thermal conductivity. Nanotechnology 21: 255704 (1-11).
Featured in Nature India:
https://www.natureasia.com/en/nindia/article/10.1038/nindia.2010.79