Codes to our most recent results are available at our GitHub repository

Published models from BioModels Database

Moreno, D.F., Jenkins, K., Morlot, S., Charvin, G., Csikász-Nagy, A., and Aldea, M. (2019). Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1 eLife, 8:e48240. Link

Moreno, D. F., Parisi, E., Yahya, G., Vaggi, F., Csikász-Nagy, A., & Aldea, M. (2019). Competition in the chaperone-client network subordinates cell-cycle entry to growth and stress. Life Science Alliance, 2(2), e201800277. Link

Hong CI, Zámborszky J, Csikász-Nagy A. Minimum criteria for DNA damage-induced phase advances in circadian rhythms. PLoS Comput. Biol. 2009 May; 5(5): e1000384

Conradie R, Bruggeman FJ, Ciliberto A, Csikász-Nagy A, Novák B, Westerhoff HV, Snoep JL. Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex. FEBS J. 2010 Jan; 277(2): 357-367

Moriya H, Chino A, Kapuy O, Csikász-Nagy A, Novák B. Overexpression limits of fission yeast cell-cycle regulators in vivo and in silico. Mol. Syst. Biol. 2011; 7: 556

Amara F, Colombo R, Cazzaniga P, Pescini D, Csikász-Nagy A, Falconi MM, Besozzi D, Plevani P. In vivo and in silico analysis of PCNA ubiquitylation in the activation of the Post Replication Repair pathway in S. cerevisiae. BMC Syst Biol 2013; 7: 24

Project dedicated websites

Honeth G, Schiavinotto T, Vaggi F, Marlow R, Kanno T, Shinomiya I, Lombardi S, Buchupalli B, Graham R, Gazinska P, Ramalingam V, Burchell J, Purushotham AD, Pinder SE, Csikasz-Nagy A, Dontu G. (2015) Models of Breast Morphogenesis Based on Localization of Stem Cells in the Developing Mammary Lobule. Stem Cell Reports 4,: 699-711.

Vaggi F, Schiavinotto T, Lawson JLD, Chessel A, Dodgson J, Geymonat M, Sato M, Carazo-Salas RE, Csikász-Nagy A (2014) A network approach to mixing delegates at meetings. eLife 3:e02273

Csikász-Nagy A, Escudero LM, Guillaud M, Sedwards S, Baum B, Cavaliere M. (2013) Cooperation and competition in the dynamics of tissue architecture during homeostasis and tumorigenesis. Seminars in Cancer Biology 23:293-298

Cavaliere M, Sedwards, S, Tarnita CE, Nowak MA, Csikász-Nagy A (2012) Prosperity is associated with instability in dynamical networks. J Theor Biol 299:126-138

Csikász-Nagy, A., Győrffy, B., Alt, W., Tyson, J.J. & Novák, B., (2008) Spatial controls for growth zone formation during the fission yeast cell cycle. Yeast, 25: 59–69.

Csikasz-Nagy A, Battogtokh D, Chen KC, Novák B & Tyson JJ. (2006) Analysis of a generic model of eukaryotic cell cycle regulation. Biophys J 90, 4361-4379

Chen KC, Calzone L, Csikasz-Nagy A, Cross FR, Novak B, Tyson JJ. (2004) Integrative Analysis of Cell Cycle Control in Budding Yeast. Mol Biol Cell 15, 3841-3862.

Recorded lectures

Spatial modelling (in Hungarian)

Fission yeast cell cycle and cell growth