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About us
About us
We are a computational biology research group at IIT Kanpur, focusing on developing cutting-edge computational methods to decode complex biological systems. Our work lies at the intersection of machine learning, bioinformatics, and single-cell genomics, aiming to uncover fundamental insights into cancer evolution, cellular heterogeneity, and disease progression.
At our lab, we integrate probabilistic modeling, graph algorithms, and statistical learning with large-scale biological data to address key challenges in evolutionary dynamics, phylogenetics, and personalized medicine. Through interdisciplinary collaboration, we strive to advance computational techniques that push the boundaries of biomedical research.
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2025
[June 2] Talk at NIBMG: Hamim delivered a talk on 'Computational analysis of single-cell and spatial omics datasets for elucidating cancer heterogeneity' at NIBMG Kalyani.
[June 1] bioRxiv alert!: The preprint of Krushna's work in collaboration with Prof. Sai Pydi's lab at IIT Kanpur on a Temporal Single-Cell Multi-Omics Atlas of Murine Pancreatic Islet Remodeling During Hyperglycaemia Progression is out now on bioRxiv. This paper had also contributions from Ajita, Shruti and Ayush.
[April 29] Publication alert!: Krushna's collaborative work in a study from Prof. Shamik Sen's lab at IIT Bombay got published in the Journal of the American Chemical Society (JACS).
[April 24-29] RECOMB 2025: Members of CoSmic lab visited RECOMB 2025 and presented their works. Ajita, Krushna, Priya, and Hamim presented posters on Spatial domain detection benchmarking, multiHIVE, PHALCON, and Renoir respectively. Hamim delivered a talk on Narein's work intratumor heterogeneity through the lens of gene regulatory networks at RECOMB-CCB. Hamim also chaired a session on Spatial Transcriptomics at RECOMB 2025.
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