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Current Projects
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3'REG1 (from human) drives cardiac GFP expression at 72 hpf (live GFP expression).
3'regM drives atrial GFP expression at 48 hpf (live GFP expression).
3'regM expression is downregulated by FK506 (Nfatc1 inhibitor) and XAV939 (Wnt inhibitor). Once combined, they do not impact 3'regM expression.
5'reg2-Nr2f1 drives GFP expression in the valves at 96hpf (heart is marked with MHC).
5'reg2-Nr2f1 expression in the valves is under the control of multiple pathways (Nfatc1, Wnt, Hedgehog) forming an intricated regulatory crosstalk.
Collaborators
Collaborators
Lyndsay Rhodes, Professor, Department of Biological Sciences, Florida Gulf Coast University, USA
Rheka Pudur, Assistant Professor, Department of Healt Sciences, Florida Gulf Coast University, USA
Mattia Quattrocelli, Assistant Professor, Heart Institute, Cincinnati Children's Hospital Medical Center, USA
Salvatore D'Aniello, First Researcher, Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Italy
Filomena Ristoratore, First Researcher, Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Italy
Angelisa Frasca, Associate Professor, Department of Medical Biotechnology and Translational Medicine. Universita' Statale di Milano, Italy
Diego Franco Jaime, Professor, Department of Experimental Biology, Universidad de Jaen, Spain
Chiara Maria Motta, Associate Professor, Department of Biology, Universita' degli Studi di Napoli "Federico II", Italy
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