The Little River is a 29.3-mile-long (47.2 km)[1] tributary of the Etowah River in the U.S. state of Georgia in the United States.

The Little River is located mostly in Cherokee County, and forms the jagged part of the Cherokee/Fulton (formerly Cherokee/Milton) county line, and part of the more recent Milton city limit.

The river flows generally from east to west, and divides the Woodstock area to the south and Holly Springs area to the north. Its largest tributary is Noonday Creek, a stream which flows north out of Cobb and through Cherokee County, and now also empties directly into the lake. The confluence with the Etowah River is now submerged beneath Lake Allatoona.

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