Embedded Files
Beveridge CH (#), Iyer S (#), Randolph CE (#), Muhberac M, Manchanda P, Walker KA, Tichy S, Chopra G(*). CLAW-MRM: Comprehensive Lipidomics Automation Workflow for Multiple Reaction Monitoring using Large Language Models. Analytical Chemistry. Accepted. 2025. arXiv [Preprint]. https://arxiv.org/abs/2403.15076 #Contributed equally
Yang M, Iqfath M, Hernly E, Tang X, Unsihuay D, Manchanda P, Sharma K, Beveridge CE, Chopra G(*), Laskin J. Multimodal Nano-DESI Mass Spectrometry Imaging Reveals Phospholipids Accumulation in and Around Amyloid Plaques in Alzheimer’s Disease. ACS Chem. Neurosci. 2025. https://doi.org/10.1021/acschemneuro.5c00144
Prakash P(#), Manchanda P(#), Paouri E, Bisht K, Sharma K, Hossain A, Rajpoot J, Wendt V, Wijewardhane PR, Randolph CE, Chen Y, Stanko S, Gasmi N, Gjojdeshi A, Card S, Fine JA, Jethava KP, Clark MG, Dong B, Ma Seohee, Crockett AM, Thayer EA, Nicolas M, Davis R, Hardikar D, Allende D, Prayson RA, Zhang C, Davalos D, Chopra G(*). Amyloid β Induces Lipid Droplet-Mediated Microglial Dysfunction via the enzyme DGAT2 in Alzheimer’s Disease. Immunity. 2025, Volume 58, Issue 6, 1536 - 1552.e8. #Contributed equally
AlzForum Research Highlight: Lipid-Laden, Sluggish Microglia? Blame Aβ.
Media coverage: https://www.thehindu.com/sci-tech/science/immune-cells-fat-blocks-brains-ability-to-cleanalzheimers-plaques/article69779865.ece
Beck AG, Fine JA, Chopra G(*). Paddy: Evolutionary Optimization Algorithm for Chemical Systems and Spaces. Digital Discovery, 2025, 4, 1352-1371. https://doi.org/10.1039/D4DD00226A
Randolph CE, Walker KA, Yu R, Beveridge CH, Manchanda P, Chopra G(*). Glial Biologist’s Guide to Mass Spectrometry-Based Lipidomics: A Tutorial from Sample Preparation to Data Analysis. Glia. 73(3): 474-494, 2025. https://doi.org/10.1002/glia.24665
Prakash P, Randolph CE, Walker KA, Chopra G(*). Lipids: Emerging Players of Microglial Biology. Glia. 73(3): 657-677, 2025. https://doi.org/10.1002/glia.24654
Bryns CN, Perlegos AE, Miller K, Jin Z, Carranza FR, Manchanda P, Beveridge CH, Randolph CE, Chaluvadi VS, Zhang SL, Srinivasan AR, Bennett FC, Sehgal A, Adams PD, Chopra G, Bonini NM. Senescent glia link mitochondrial dysfunction and lipid accumulation. Nature. 630, 475–483 (2024). https://doi.org/10.1038/s41586-024-07516-8.
AlzForum Research Highlight: Neuron-Glia Crosstalk Underlies Senescence, Impaired Lipid Metabolism
Publication Highlight: Reyes JF, Devarajan M, Cai D, Mashek DG. Senescent glia — bridging neuronal mitochondrial dysfunction and lipid accumulation in aging, Life Metabolism, 2024;, loae031, https://doi.org/10.1093/lifemeta/loae031
Ramdas B#, Dayal N#, Pandey R, Larocque E, Pasupuleti SK, Liu S, Kanellopoulou C, Chu ERFY, Ferreira RM, Virani S, Chopra G, Aryal UK, Lapidus R, Wan J, Emadi A, Holtsberg FW, Aman MJ, Sintim HO, Kapur R. Alkynyl nicotinamides with antileukemic activity for treating poor prognosis AML. J. Clin. Invest. 134(12): e169245. (2024). https://doi.org/10.1172/JCI169245. #Contributed equally
Beck AG#, Evans BR#, Yeung L, Li A, Lee DH, Bateman KP, Chopra G*. Automated Bioanalytical Workflow for Ligand Binding based Pharmacokinetic Assay Development. Anal. Chem. 96, 1, 488–495. (2024). DOI: https://doi.org/10.1021/acs.analchem.3c04589 #Contributed equally
Beck AG, Muhoberac M, Randolph CE, Beveridge CH, Wijewardhane PR, Kenttämaa HI, Chopra G*. Recent Developments in Machine Learning and Artificial Intelligence for Mass Spectrometry. ACS Meas. Sci. Au. 2024, 4, 233-246.
2023 Rising Stars in Measurement Science: S. Minteer ACS Measurement Science Au 2024 4 (2), 144-152. DOI: 10.1021/acsmeasuresciau.4c00013
Randolph CE, Manchanda P, Arora H, Iyer S, Saklani P, Beveridge C, Chopra G. Mass Spectrometry-based Single-Cell Lipidomics: Advancements, Challenges, and the Path Forward. TrAC Trends in Analytical Chemistry. Volume 169, 117350 (2023). DOI: https://doi.org/10.1016/j.trac.2023.117350
Santhakumari PR, Dhanabalan KV, Virani S, Hopf-Jannasch AS, Benoit JB, Chopra G, Subramanian R. Variability in phenylalanine side chain conformations facilitates broad substrate tolerance of fatty acid binding in cockroach milk proteins. PLoS ONE. 18(6): e0280009 (2023). DOI: https://doi.org/10.1371/journal.pone.0280009
Fine JA, Wijewardhane PR, Mohideen Beer SD, Smith K, Bothe J, Krishnamachari Y, Andrews A, Liu Y, Chopra G(*). Learning relationships between chemical and physical stability for peptide drug development. Pharm Res. 40, 701-710 (2023). #Contributed equally DOI: https://doi.org/10.1007/s11095-023-03475-3
Randolph CE, Beveridge CH, Iyer S, Blanksby SJ, McLuckey SA, Chopra G(*). Identification of monomethyl branched chain lipids by a combination of liquid chromatography tandem mass spectrometry and charge-switching chemistries. Journal of the American Society for Mass Spectrometry. 33(11): 2156-2164 (2022). DOI: https://doi.org/10.1021/jasms.2c00225
Falls Z, Fine J, Chopra G(*), Samudrala R. Accurate prediction of inhibitor binding to HIV-1 protease using CANDOCK. Front. Chem. 9 (2022). DOI: https://doi.org/10.3389/fchem.2021.775513
Jethava KP(P,#), Prakash P(G,#), Manchanda P(G), Arora H(G), Chopra G(*). One Scaffold – Different Organelles Sensors: pH-Activable Fluorescent Probes for Targeting Live Microglial Cell Organelles. ChemBioChem. 23, 9, e202100378. (2022). DOI: https://doi.org/10.1002/cbic.202100378 #Contributed equally
Guttenplan K, Weigel MK(#), Prakash P(G,#), Wijewardhane PR(G), Hasel P, Rufen-Blanchette U, Münch AE, Blum JA, Fine J(G), Neal M, Bruce KD, Gitler AD, Chopra G, Liddelow SA, Barres B. Neurotoxic reactive astrocytes induce cell death via saturated lipids. Nature. 599, 102–107 (2021). DOI: https://doi.org/10.1038/s41586-021-03960-y. #Contributed equally
AlzForum Research Highlight: ELOVL hurts—enzyme makes lipids that turn astrocytes toxic.
Genetic Engineering and Biotechnology News: Toxic fatty acids could represent new target for treating neurodegenerative disorders.
Times Now News India: Cure for dementia and Parkinson’s in sight? Scientists find cells that cause neurological diseases.
Prakash P(G), Jethava KP(P), Korte N, Izquierdo P, Favuzzi E, Rose IVL, Guttenplan KA, Manchanda P(G), Dutta S, Rochet J-C, Fishell G, Liddelow S, Attwell D, Chopra G(*). Monitoring phagocytic uptake of amyloid-b into glial cell lysosomes in real-time. Chem Sci. 12, 10901-10918 (2021) DOI: https://doi.org/10.1039/D1SC03486C
Fine JA(G), Anand AR(U), Jethava KP(P), Chopra G(*). Spectral deep learning for prediction and prospective validation of functional groups. Chem. Sci. 11, 4618-4630 (2020). DOI: https://doi.org/10.1039/C9SC06240H
2020 Chemical Science Pick of the Week Collection
2020 Chemical Science HOT Article Collection and Accelerating Chemistry Symposium Collection
Fine JA(G), Li JK-Y, Beck A(G), Alzarieni KZ, Ma X, Boulos V, Kenttämaa, HI, Chopra G(*). Graph based machine learning interprets and predicts diagnostic isomer-selective ion-molecule reactions in tandem mass spectrometry. Chem. Sci. 11, 11849-11858 (2020). DOI: https://doi.org/10.1039/D0SC02530E
Media cover: Drug Discovery News , Phys Org, Eureka Alert, Purdue Newsroom, Lab Manager, Newsbreak.
Arya CK, Yadav S, Fine JA(G), Casanal A, Chopra G(*), Ramanathan G, Vinothkumar KR, Subramanian R. A 2-Tyr-1-Carboxylate Mononuclear Iron Center is the Active Site of Dimethylformamidase. Angew Chemie. Int. Ed. 59, 39, 16961-16966 (2020). DOI: https://doi.org/10.1002/anie.202005332
Jethava KP, Fine JA, Chen Y, Hossain A, Chopra G. Accelerated reactivity mechanism and interpretable machine learning model of N-Sulfonylimines toward fast multicomponent reactions. Org. Lett. 22, 21, 8480–8486 (2020). DOI: https://doi.org/10.1021/acs.orglett.0c03083
Media cover: Drug Discovery Trends, Purdue Newsroom
Mangione W, Falls Z, Melendy T, Chopra G, Samudrala R. Shotgun drug repurposing biotechnology to tackle epidemics and pandemics. Drug Discov. Today. 25, 7, 1126-1128 (2020). DOI: https://doi.org/10.1016/j.drudis.2020.05.002
Fine JA, Muhoberac M, Fraux G, Chopra G. DUBS: A framework for developing Directory of Useful Benchmarking Sets for virtual screening. J. Chem. Inf. Model. 60, 9, 4137-4143 (2020). DOI: https://doi.org/10.1021/acs.jcim.0c00122
Mangione W, Falls Z, Chopra G, Samudrala R. cando.py: Open source software for analyzing large scale drug-protein-disease data. J. Chem. Inf. Model. 60, 9, 4131-4136 (2020). DOI: https://doi.org/10.1021/acs.jcim.0c00110
Robertson MA, Padgett LR, Fine JA, Chopra G, Mastracci TL. Targeting polyamine biosynthesis to stimulate beta cell regeneration in zebrafish. Islets. Sep 2;12(5):99-107 (2020). DOI: https://doi.org/10.1080/19382014.2020.1791530
Fine JA, Konc J, Samudrala R, Chopra G. CANDOCK: Chemical atomic network based hierarchical flexible docking algorithm using generalized statistical potentials. J. Chem. Inf. Model. 60, 3, 1509-1527 (2020). DOI: https://doi.org/10.1021/acs.jcim.9b00686
Chakravorty S, Yan B, Wang C, Wang L, Quaid JT, Lin CF, Briggs SD, Majumder J, Canaria DA, Chauss D, Chopra G, Olson M, Zhao B, Afzali B, Kazemain M. Integrated pan-cancer map of EBV-associated neoplasms reveals functional host-virus interactions. Cancer Res. 79, 23, 6010-6023 (2019). DOI: https://doi.org/10.1158/0008-5472.CAN-19-0615.
Media cover: Medical Xpress, Health Canal
Fine JA, Lackner R, Samudrala R, Chopra G. Computational chemoproteomics to understand the role of selected psychoactives in treating mental health indications. Sci. Rep., 9:13155 (2019). https://doi.org/10.1038/s41598-019-49515-0
Media cover: Med India, Technology Networks, News Medical, Greensburg Daily News, Medical Xpress.
Fine JA, Chopra G. Lemon: a framework for rapidly mining structural information from the Protein Data Bank.Bioinformatics, 35(20):4165-67 (2019). https://doi.org/10.1093/bioinformatics/btz178
Media cover: Health IT Analytics, Eureka Alert, Science Daily, Sci Tech Daily, Tech Xplore, Global Spec, Indica News
Prakash P, Lantz TC, Jethava KP, Chopra G(*). Rapid, Refined, and Robust Method for Expression, Purification, and Characterization of Recombinant Human Amyloid-beta 1-42. Methods and Protocols, 2(2), 48. (2019). https://doi.org/10.3390/mps2020048
Keasar C, McGuffin LJ, Wallner B, Chopra G, et. al. An analysis and evaluation of the WeFold collaborative for protein structure in CASP11 and CASP12. Sci. Rep., 8, 9939 (2018).
Contribution: Development of biophysical methods and modules for protein structure refinement.
Hernandez-Perez M, Chopra G, Fine J, Anderson RM, Benjamin C, Nadler JL, Holman TR, Maloney DJ, Tersey SA, Mirmira RG. Inhibition of 12/15-lipoxygenase protects against β cell oxidative stress and glycemic deterioration in mouse models of type 1 diabetes. Diabetes, 66 (11), 2875-2887 (2017).
Contribution: Proteome-scale modeling to identify toxicity and 12/15-lipoxygenase interaction modeling of small molecules validated by experiments done in the manuscript. These methods are based on previous work from my lab.
Larocque E, Nimmeshetti N, Ma X, Opoku-Temeng C, Chopra G, Sintim HO. Aminoisoquinoline benzamides, FLT3 and Src-family kinase inhibitors, potently inhibit acute myeloid leukemia cell lines. Future Med Chem. 9(11): 1213-1225 (2017).
Ma X, Zhou J, Wang C, Carter-Cooper B, Yang F, Larocque E, Fine JA, Tsuji G, Chopra G, Lapidus RG, Sintim HO. Identification of new FLT3 inhibitors that potently inhibit AML cell lines, via an azo click-it/staple-it approach. ACS Med Chem Lett. 8(5), pp 492-497 (2017).
Media cover: Tech Science Daily News
Chopra G, Kaushik S, Elkin PL, White G, Samudrala R. Combating Ebola with repurposed therapeutics using the CANDO platform. Molecules 21(12): 1537 (2016).
Esensten JH, Helou YA, Chopra G, Weiss A, Bluestone JA. CD28 costimulation: from mechanism to therapy. Immunity 44(5): 973-988 (2016).
Chopra G, Samudrala R. Exploring polypharmacology in drug discovery and repurposing using the CANDO platform. Current Pharm. Des. 22(21): 3109-3123 (2016).
Publications from Postdoctoral and Graduate Research
Publications from Postdoctoral and Graduate Research
Chopra G, Sethi G#, Samudrala R. Multiscale modeling of relationships between protein classes and drug behavior across all diseases using the CANDO platform. Mini Reviews in Medicinal Chemistry 15(8): 705-17 (2015). #Contributed equally
DuPage M, Chopra G, Quiros J, Rosenthal WL, Morar MM, Holohan D, Zhang R, Turka L, Marson A, Bluestone JA. The chromatin-modifying enzyme Ezh2 is critical for the maintenance of regulatory T-cell identity. Immunity 42(2): 227-38 (2015). [pubmed]
Ali ZA, de Jesus Perez V, Yuan K, Orcholski M, Pan S, Qi W, Chopra G, Adams C, Kojima Y, Leeper NJ, Qu X, Zaleta-Rivera K, Kato K, Yamada Y, Oguri M, Kuchinsky A, Channon K, Charest A, Quertermous T, Ashley EA. Oxido-reductive regulation of human vascular remodeling by the orphan receptor tyrosine kinase ROS1. J. Clinical Investigation 124(12): 5159-74 (2014).
Media cover: Medical Xpress, News Wise, Science Daily.
Chopra G#, Minie ME#, Sethi G#, Horst JA#, Roy A, White G, Samudrala R. CANDO and the infinite drug discovery frontier. Drug Discov. Today 19(9):1353-63 (2014). #Contributed equally
Khoury GA, Liwo A, Khatib F, Zhou H, Chopra G, Bacardit J, Bortot LO, et. al. WeFold: Large-scale Coopetition for Protein Structure Prediction. Proteins 82(9):1850-1868 (2014).
Lertkiatmongkol P, Assawamakin A, White G, Chopra G, Rongnoparut P, Samudrala R, Tongsima S. Distal effect of amino acid substitutions in CYP2C9 polymorphic variants causes differences in interatomic interactions against (S)-warfarin. PLoS One 8(9): e74053 (2013).
Horst JA, Pieper U, Sali A, Zhan L, Chopra G, Samudrala R & Featherstone JDB. Strategic protein target analysis for developing drugs to stop dental caries. Adv. Dent. Res. 24(2): 86-93 (2012).
Rodrigues J, Levitt M and Chopra G. KOBAMIN – KnOwledge BAsed MINimization server for protein structure refinement. Nucleic Acid Research, Web Server Issue. 40 (W1): W323-W328 (2012).
Chopra G and Levitt M. Remarkable patterns of surface water ordering around polarized buckminsterfullerene. Proc. Natl. Acad. Sci. U.S.A. 108(35):14455-14460 (2011).
Media cover: Phys Org
Chopra G, Kalisman N & Levitt M. Consistent refinement of submitted models at CASP using a knowledge-based potential. Proteins 78(12): 2668-2678 (2010).
Chopra G, Summa CM & Levitt M. Solvent dramatically affects protein structure refinement. Proc. Natl. Acad. Sci. U.S.A. 105(51): 20239-20244 (2008).
Submitted and in Revision after Review
Submitted and in Revision after Review
Prakash P, Manchanda P, Paouri E, Bisht K, Sharma K, Hossain A, Wijewardhane PR, Randolph CE, Clark MG, Fine JA(G), Wendt V(U), Thayer EA(U), Jethava K, Davis R, Prayson RA, Zhang C, Davalos D, Chopra G(*). Amyloid β Induces Lipid Droplet-Mediated Microglial Dysfunction in Alzheimer’s Disease. Immunity. Revision after review. 2024. #Contributed equally. PMCID: PMC10274698. biorxiv [Preprint]. Available from (doi): https://doi.org/10.1101/2023.06.04.543525
AlzForum Research Highlight: Lipid-Laden, Sluggish Microglia? Blame Aβ.
McCallum S, Suresh KB, Islam T, Saustad AW, Shelest O, Patil A, Lee DD, Kwon B, Yenokian I, Kawaguchi R, Beveridge CH, Manchanda P, Randolph CE, Meares GP, Plummer JT, Dutta R, Knott SRV, Chopra G, Burda JE. Lesion-remote astrocytes govern microglia-mediated white matter repair. Nature. Revision after review. 2024. #Contributed equally. PMCID: PMC10979953. bioRxiv [Preprint]. Available from (doi): https://doi.org/10.1101/2024.03.15.585251
Beck AG, Fine JA, Chopra G(*). Paddy: Evolutionary Optimization Algorithm for Chemical Systems and Spaces. Digital Discovery. With Reviewers. 2024. arXiv [Preprint]. https://arxiv.org/abs/2403.15101
Beveridge CH, Iyer S, Randolph CE, Muhberac M, Manchanda P, Clingenpeel AC, Tichy S, Chopra G(*). Comprehensive Lipidomic Automation Workflow using Large Language Models. Nature Methods. Submitted. 2024. arXiv [Preprint]. https://arxiv.org/abs/2403.15076
Wijewardhane PR, Wells A, Muhoberac M, Leung KP, Chopra G(*). Modeling Molecular Mechanisms of Pirfenidone Interaction with Kinases. J. Chem. Inf Mod. Submitted. 2024. bioRxiv 586235 [Preprint]. Available from (doi): https://doi.org/10.1101/2024.03.22.586235
Wijewardhane PR, Jethava KP, Fine JA, Chopra G(*). Graph neural networks bootstrapped for synthetic selection and validation of small molecule immunomodulators. chemRxiv [Preprint]. Available from (doi): https://doi.org/10.33774/chemrxiv-2021-r4xnx-v2 #Contributed equally
Fine JA, Dhawan D, Utturkar S, San Miguel P, Chopra G, Turek J, Nolte D, Childress MO, Lanman NA. Integration of Biodynamic Imaging and RNA-seq predicts chemotherapy response in canine diffuse large B-cell lymphoma. bioRxiv 290353 [Preprint]. Available from (doi): https://doi.org/10.1101/2020.09.11.290353
Zhang W, Fine JA, Sculley C, McGraw J, Chopra G(*). Molecular Interactions using New Technology: A virtual reality gaming platform to visualize and manipulate molecules. chemRxiv 9889994 [Preprint]. Available from (doi): https://doi.org/10.26434/chemrxiv.9889994.v1.
Hossain A, Majumder J, Bi C, Huang F, Chopra G(*). Stable and Reversible Functionalization and Super-Resolution Microscopy of Live Cell Membranes. bioRxiv 462044 [Preprint]. Available from (doi): https://doi.org/10.1101/462044 #Contributed equally
Randolph CE, Walker KA, Yu R, Beveridge CH, Manchanda P, Chopra G(*). Glial Biologist’s Guide to Mass Spectrometry-Based Lipidomics: A Tutorial from Sample Preparation to Data Analysis. Glia. With Reviewers. 2024.
Prakash P, Randolph CE, Walker KA, Chopra G(*). Lipids: Emerging Players of Microglial Biology. Glia. With Reviewers. 2024.
Vicidomini C, GoodeTD, McAvoy KM, Ruilin Yu, Beveridge CH, Iyer SN, Victor MB, Leary N, Evans L, Steinbaugh MJ, Lai ZW, Lyon MC, Silvestre MRFS, Bonilla G, Sadreyev RI, Walther TC, Sui SH, Saido T, Yamamoto K, Murakami M, Tsai L-H, Chopra G, Sahay A. An aging-sensitive compensatory secretory phospholipase that confers neuroprotection and cognitive resilience. Nature Neuroscience. With Reviewers. 2024. biorxiv [Preprint]. https://doi.org/10.1101/2024.07.26.605338
Refereed Published Abstracts & Non-refereed Publications
Refereed Published Abstracts & Non-refereed Publications
Ramdas B, Dayal N,Pandey R, Larocque E, Pasupuleti SK, Liu S, Kanellopoulou C, Chu ERFY, Ferreira RM, Virani S, Chopra G, Aryal UK, Lapidus R, Wan J, Emadi A, Holtsberg FW, Aman MJ, Sintim HO, Kapur R. Alkynyl nicotinamides with antileukemic activity for treating poor prognosis AML. Experimental Hematology, Volume 124, Supplement, 2023, Page S129, ISSN 0301-472X.
Chakravorty S, Yan B, Chauss D, Wang L, Canaria DA, Jethava K, Chopra G, Briggs SD, Zhao B, Olson MR, Afzali B, Kazemian M. The role of Virostatic genes in modulating Immune Checkpoints in Epstein-Barr Virus associated Tumors. J Immunol May 1, 2020, 204 (1 Supplement) 249.9.
Thayer EA, Prakash P, Fine JA, Ferreira CR, Chopra G(*). Lipidomic profiling in amyloid beta treated BV2 microglia. 4th Annual ECI Undergraduate Research Conference, November 16th, 2019; University of Illinois Urbana-Champaign, Champaign, IL. (presented by undergraduate student)
Thayer EA, Prakash P, Chopra G(*). Amyloid-beta mediated inflammatory response in microglia. Summer Undergraduate Research Fellowship (SURF) Symposium. (August 2019).
Kischuk E, Majumder J(P), Fine JA(G), Lantz TC(U), Dhawan D, Knapp DW, Ratliff TL, Chopra G(*). Cell-specific gene program-based small-molecule immunomodulators targeting solid-tumor microenvironments. Cancer Research 78 (13 Supplement), 4709-4709, (2018).
Myoung S, Savinov S, Chen L, Chopra G, Avramova L, Welch J, Loren B, Thompson D, Kasinski AL. Development of an RNA-based cancer therapeutic targeting the let-7-LIN28 interaction. Cancer Research 78 (13 Supplement), 4656-4656, (2018).
Thayer EA(U), Prakash P(G), Chopra G. Role of cyclic GMP-AMP Synthase (cGAS) in Microglial Immune Response. 3rd Annual ECI Undergraduate Research Conference, November 17th, 2018; University of Illinois Urbana Champaign, Champaign, IL. (presented by undergraduate student)
Williams GC, Prakash P, and Chopra G(*). Targeting pro-inflammatory function of microglia using small molecules to combat neurodegeneration. Summer Undergraduate Research Fellowship (SURF) Symposium. Paper 100 (2018). (presented by undergraduate student)
Chopra G. Targeting Proteome-Scale Networks to Design and Synthesize Potent Anticancer and Cell-Specific Immunomodulatory Compounds. Biophysical Journal, Volume 114, Issue 3, Supplement 1, p663a, 2 February 2018. DOI: https://doi.org/10.1016/j.bpj.2017.11.3577.
Majunder J, Chopra G(*). Live Cell Surface Conjugation Methods for Imaging, Sensing and Therapy. Biophysical Journal, Volume 114, Issue 3, Supplement 1, p20a, 2 February 2018. DOI: https://doi.org/10.1016/j.bpj.2017.11.154.
Fine J, Chopra G(*). CANDOCK: Conformational Entropy Driven Analytics for Class-Specific Proteome-Wide Docking. Biophysical Journal, Volume 114, Issue 3, Supplement 1, p57a, 2 February 2018. DOI: https://doi.org/10.1016/j.bpj.2017.11.363.
McGraw J, Zhang W, Luginbuhl AD, Takahashi G, Tasker RF, Chopra G(*). Virtual Reality Environment to Visualize and Manipulate Molecular Structures. Biophysical Journal, Volume 114, Issue 3, Supplement 1, p184a, 2 February 2018. DOI: https://doi.org/10.1016/j.bpj.2017.11.1029.
Majunder J, Lantz TC, Fine J, Chopra G(*). Drug repurposing for castration resistant prostate cancer based on disease-disease relationships [abstract]. In: Proceedings of the AACR Special Conference on Translational Control of Cancer: A New Frontier in Cancer Biology and Therapy; 2016 Oct 27-30; San Francisco, CA. Philadelphia (PA): AACR, Cancer Res, 77(6 Suppl): Abstract nr A35 (2017).
Lantz TC(U), Majumder J(P), and Chopra G(*). Computational Drug Design: A Multitargeted Approach in Bladder Cancer. Summer Undergraduate Research Fellowship (SURF) Symposium. Paper 133 (2017). (presented by undergraduate student)
Stewart B(U), Fine J(G), Chopra G(*). Parallelization of Molecular Docking algorithms using CUDA for use in Drug Discovery. Summer Undergraduate Research Fellowship (SURF) Symposium. Paper 136 (2017). (presented by undergraduate student)
Xu D, Dong S, Martínez-Llordella M, Chopra G, Bluestone JA. Unveiling the specificity of islet-antigen specific regulatory T cells in T1D patient using single cell deep-sequencing. Journal of Immunology 196 (1 Supplement), 54.29-54.29 (2016).
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