Research summary

• Mechanisms of cell fate decision in tissue regeneration and diseases

• Immune system in Stem Cell Plasticity and Niche Remodelling

Fundamental Questions

• How do stem cells sense the surroundings and determine their fate and function in response to injury response?

• How do stem cells integrate the environmental stimuli? Is there genetic and epigenetic regulatory programmes?

• How does inflammation elicited by immune system coordinate the tissue regeneration?

• How are regeneration programmes hijacked and maladapted in human chronic diseases?