Engineering bioinspired drug/gene-delivery scaffolds for directing cell fate
The Chew Lab engineers bio-functional micro- and nano-structured scaffolds to understand and direct cellular behavior. We use combinatorial approaches involving substrate topography/compliance and biochemical cues from drugs, genes and cells to mediate tissue regeneration and host-implant integration.
Our works range from fundamental science to scaffold, drug/gene/cell delivery technology development; and translational research. Currently, the Chew Lab focuses on scaffold-mediated gene-silencing approaches to understand and direct neural tissue regeneration, stem cell differentiation and host-implant integration.
The Chew Lab's main objective is to provide improved platforms for better understanding and control over cell fate for regenerative medicine.
Mar 2026: 3D-printed scaffolds encapsulating red-blood-cell-derived extracellular vesicles for microRNA delivery, published in Cell Biomaterials.
Mar 2026: We are recruiting Ph.D. students. Scholarships available for multiple research areas:
- Neural Tissue Engineering (Stem cells)
- Neural Tissue Engineering (Immune response)
- Biophysical Cell Analysis and Sorting Instrumentation
Dec 2025: We are hiring for our ReVivoCellS project. More details here.
Aug 2025: Sustained MicroRNA delivery enhanced remyelination and functional recovery after spinal cord injury, published in Biomaterials.
May 2025: We are recruiting highly motivated Ph.D. students. Check out details.
May 2025: 'Bioprinted Microchannel Scaffolds Modulate Neuronal Differentiation of Encapsulated Human Spinal Cord Progenitor Cells', published in ACS Applied Bio Materials.
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