Heartbeat-evoked potentials (HEPs) provide an electrophysiological marker of cortical responses to cardiac signals. While widely studied in humans, their analysis in rodent models remains methodologically challenging. This project aims to develop and evaluate a reproducible processing pipeline for extracting HEPs from EEG and ECG recordings in freely behaving mice. By adapting established human HEP methodologies to murine electrophysiology, this work seeks to facilitate the investigation of the neural mechanisms underlying cardiac interoception and strengthen translational research on brain–heart interactions.

Gastrointestinal dysfunction is common in anorexia nervosa, yet the relationship between gastric electrophysiological activity and gastrointestinal symptoms remains poorly understood. This project investigates gastric electrical activity and its relationship with meal-related gastrointestinal symptoms in individuals with anorexia nervosa and healthy controls. Using high-resolution Body Surface Gastric Mapping, we characterize gastric electrophysiological responses to food intake while simultaneously monitoring subjective gastrointestinal sensations. This approach aims to improve our understanding of the physiological mechanisms underlying gastrointestinal disturbances in anorexia nervosa.