🤖🩺 I recommend this concise paper on the ethical and regulatory challenges of artificial intelligence (#AI) in #medicine. A clear and accessible review for healthcare professionals who are not yet familiar with these topics.Â
🔗 https://www.sciencedirect.com/science/article/pii/S0953620526004772
🧠🎯 A highly valuable roadmap toward actionable biomarkers in precision psychiatry.
A few points particularly resonated with me:
• The paper clearly reminds us why translating biomarkers into clinical applications remains particularly challenging in psychiatry, from diagnostic heterogeneity to variable treatment response.
• The major bottleneck is increasingly translation, not biomarker discovery: the field needs robust pathways to move promising biological signals toward clinically actionable biomarkers.
• Multimodal biomarkers are attractive, but complexity is not automatically better. A useful reminder of Occam’s razor, or the principle of parsimony in science: when equally informative, simpler is better.
• EEG biomarkers still have substantial untapped potential for clinical applications, an area I have been fortunate to work on with Sahib Khalsa over the past few years.
🔗 Heartbeat-evoked potential (HEP) alterations in generalized anxiety disorder: https://www.nature.com/articles/s41386-024-01806-5
🔗 EEG markers of gastrointestinal interoception in anorexia nervosa: https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2850389
• Finally, standardization and replication are critical. This particularly resonates with my own work on the HEP, for which recent reviews have highlighted substantial methodological heterogeneity, reinforcing the need for standardized methods to improve reproducibility and comparability across studies.
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This is a remarkably comprehensive roadmap that will undoubtedly help guide the next steps toward precision psychiatry. A seminal contribution to the field!