Contact Us


Joseph Castellano, Ph.D.

Icahn School of Medicine at Mount Sinai

Department of Neuroscience, Friedman Brain Institute

Ronald M. Loeb Center for Alzheimer’s disease

1425 Madison Ave, 10-70D (Box 1065 for mail)

New York, NY 10029

E: joseph.castellano[at]

Icahn Lab Website

Lab Address

Castellano Lab, Icahn School of Medicine at Mount Sinai

Icahn Building, 10-52

1425 Madison Ave

New York, NY 10029

T: (212) 659-8638

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Join Us!

Postdoctoral Position Available

The Castellano laboratory at the Icahn School of Medicine at Mount Sinai is looking for a talented a Postdoctoral Fellow to join our group! Our lab is in the Department of Neuroscience and a member of the Friedman Brain Institute and Ronald Loeb Center for Alzheimer’s disease.

Successful candidates will join a new team that conduct a range of sophisticated techniques, including parabiosis, in vivo microdialysis, and next-generation sequencing. We also employ conventional methodologies, including confocal microscopy, molecular cloning techniques, viral-mediated gene transfer, and behavioral studies to understand processes of synaptic plasticity and memory in rodent models of aging and Alzheimer’s disease. We are seeking a creative, highly motivated individual with a recent Ph.D. (less than one year) in Neuroscience or a related field who will pursue a funded project related to APOE risk and immune interactions regulating brain health. Expertise in molecular biology, rodent handling, microscopy, and basic biochemical techniques is required and experience in next-generation sequencing (bulk or single-cell) is preferred but not required. Interested candidates should send a cover letter, a CV (include details of technical expertise), and the contact information of 3 referees to Joseph.Castellano[at] Click here to apply through Mount Sinai.

Intern/Volunteer Position Available

We are actively seeking current undergraduates or recently graduated students who are motivated and excited to deepen their laboratory experience. Mentored lab experiences are available for students at this level to learn new techniques, work on a hypothesis-driven project, and to enhance critical reasoning and technical skills in preparation for graduate or medical school. Interested candidates should send CV (include details of technical expertise) along with contact information of mentors from previous laboratory experiences. Please send directly to Joseph.Castellano[at]

Graduate Student Positions

We are accepting students for rotations for the Fall! Masters student positions are also available. Please email Joseph.Castellano[at] to inquire.